Lopressor

Atrial Fibrillation, Thyroid Crisis, Migraine + 9 more
Treatment
4 FDA approvals
20 Active Studies for Lopressor

What is Lopressor

MetoprololThe Generic name of this drug
Treatment SummaryMetoprolol is a type of medication used to lower blood pressure and reduce the risk of heart problems. It is available as an immediate-release or extended-release formulation. The medicine was developed in 1969 and approved by the FDA in 1978. Metoprolol is one of the most commonly prescribed medications for heart-related problems in the United States, Netherlands, and New Zealand.
Lopressoris the brand name
image of different drug pills on a surface
Lopressor Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lopressor
Metoprolol
1978
983

Approved as Treatment by the FDA

Metoprolol, also known as Lopressor, is approved by the FDA for 4 uses including Hypertensive disease and Hypertension .
Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide
Hypertension
Used to treat nonresponsive to antihypertensive monotherapy in combination with Hydrochlorothiazide
Hemodynamically Stable
Heart Attack

Effectiveness

How Lopressor Affects PatientsMetoprolol is a drug used to treat heart rate and cardiac output issues. It works by slowing the electrical signals that control the heart and reducing the amount of blood the heart pumps out. The MAPHY trial showed that metoprolol reduced sudden cardiac death and heart attack when compared to diuretics. Another 1990 study found that taking metoprolol after a heart attack reduced the risk of death and repeat heart attack by 17%.
How Lopressor works in the bodyMetoprolol works by blocking certain receptors in the heart. This reduces the heart's rate and strength of contractions, without affecting other parts of the body.

When to interrupt dosage

The measure of Lopressor is contingent upon the diagnosed disorder, for example Hemodynamically Stable, Thyroid Crisis and Atrial Fibrillation. The magnitude of dosage is contingent on the technique of delivery (e.g. Tablet, coated or Tablet - Oral) featured in the table beneath.
Condition
Dosage
Administration
Chest Pain
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Heart Attack
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Hypertensive disease
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Hypertension
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Migraine Disorders
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Atrial Fibrillation
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Thyroid Crisis
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Migraine
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Hypesthesia
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Hypesthesia
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Hemodynamically Stable
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral
Tachycardia, Supraventricular
, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg
, Oral, Tablet - Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

Lopressor Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Metoprolol may interact with Pulse Frequency
Heart Block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Heart Decompensation
Do Not Combine
Pulse Frequency
Do Not Combine
severe bradycardia
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
There are 20 known major drug interactions with Lopressor.
Common Lopressor Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Metoprolol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Metoprolol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Metoprolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Metoprolol.
Agrostis stolonifera pollen
Major
The risk of a hypersensitivity reaction to Agrostis stolonifera pollen is increased when it is combined with Metoprolol.
Lopressor Toxicity & Overdose RiskThe lethal dose of metoprolol in rats has been found to be between 3090 and 4670 mg/kg. Overdosing on metoprolol may cause a slow heartbeat, low blood pressure, difficulty breathing, and heart failure. To treat an overdose, doctors recommend emptying the stomach and then providing treatment based on the symptoms. Metoprolol has not been linked to cancer, mutations, or fertility problems, although long-term use of high doses may cause minor lung tumors.
image of a doctor in a lab doing drug, clinical research

Lopressor Novel Uses: Which Conditions Have a Clinical Trial Featuring Lopressor?

Currently, 319 active studies are assessing the potential of Lopressor in providing relief from Hypesthesia, Thyroid Crisis and Hypertensive diseases.
Condition
Clinical Trials
Trial Phases
Atrial Fibrillation
96 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Chest Pain
2 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Thyroid Crisis
0 Actively Recruiting
Hypesthesia
10 Actively Recruiting
Not Applicable, Phase 1
Hemodynamically Stable
0 Actively Recruiting
Tachycardia, Supraventricular
0 Actively Recruiting
Migraine
52 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Hypesthesia
2 Actively Recruiting
Not Applicable
Hypertension
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Migraine Disorders
1 Actively Recruiting
Phase 3

Lopressor Reviews: What are patients saying about Lopressor?

5Patient Review
11/23/2017
Lopressor for High Blood Pressure
I've been taking this treatment for 34 years with no issues and great results.
5Patient Review
6/16/2013
Lopressor for Myocardial Reinfarction Prevention
This medication has been effective with no negative side effects, which is great.
4.3Patient Review
4/29/2013
Lopressor for High Blood Pressure
3.7Patient Review
3/14/2021
Lopressor for High Blood Pressure
I've only been taking metoprolol for a week, but my blood pressure is already lower. However, my heart rate is still pretty high (up to 100 beats per minute).
3.3Patient Review
8/1/2014
Lopressor for High Blood Pressure
I haven't been too impressed with this medication. I've been taking it for about a month now and have experienced some bruising, constipation, and sexual side effects that weren't present before. I'm going to continue to monitor these effects.
View All Reviews
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Patient Q&A Section about lopressor

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Lopressor a blood thinner?

"No, metoprolol does not thin the blood. Instead, it works to relax blood vessels and slow heart rate."

Answered by AI

What are the side effects of Lopressor?

"You may feel dizzy, tired, or depressed. You may also have confusion, memory problems, nightmares, trouble sleeping, diarrhea, or a mild itching or rash."

Answered by AI

What is drug Lopressor used for?

"This medication can help lower your blood pressure to prevent strokes, heart attacks, and kidney problems. It is also used to treat chest pain (angina) and improve your survival after a heart attack."

Answered by AI

Is metoprolol and Lopressor the same?

"Generic name for Lopressor is Metoprolol tartrate. It is a beta blocker used to treat high blood pressure and chronic chest pain. Feb 18, 2020"

Answered by AI

Clinical Trials for Lopressor

Have you considered Lopressor clinical trials? We made a collection of clinical trials featuring Lopressor, we think they might fit your search criteria.
Have you considered Lopressor clinical trials? We made a collection of clinical trials featuring Lopressor, we think they might fit your search criteria.
Have you considered Lopressor clinical trials? We made a collection of clinical trials featuring Lopressor, we think they might fit your search criteria.
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