Livalo

Q: What are the side effects of Livalo?

<p>You may experience muscle pain, <a href="https://www.withpower.com/clinical-trials/back-pain">back pain</a>, joint pain, pain in your arms and legs, diarrhea, constipation, skin rash, or headache.</p>

Q: What is special about Livalo?

<p>Livalo is a <a href="https://www.withpower.com/clinical-trials/cholesterol">cholesterol</a>-lowering medication for adults with high cholesterol. It helps to lower total cholesterol, "bad" cholesterol (LDL-C), triglycerides, and Apo B. It also raises "good" cholesterol (HDL-C).</p>

Hyperlipidemia, Hypercholesterolemia, Dyslipidemias

Treatment

5 FDA approvals

3 Active Studies for Livalo

Treatment for

Hyperlipidemia

What is Livalo

PitavastatinThe Generic name of this drug

Treatment SummaryPitavastatin, marketed under the name Livalo, is a type of cholesterol-lowering drug called a statin. Statins work by blocking an enzyme that helps the body produce cholesterol. This drug and other statins, such as atorvastatin, pravastatin, rosuvastatin, fluvastatin and lovastatin, are typically prescribed to people who are at risk of developing cardiovascular disease, such as those with type 2 diabetes. Pitavastatin has been proven to be effective in lowering LDL-C (bad cholesterol) and increasing HDL-C (good cholesterol), and is

Livalois the brand name

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Livalo Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Livalo

Pitavastatin

2010

Approved as Treatment by the FDA

Pitavastatin, also called Livalo, is approved by the FDA for 5 uses including Heterozygous Familial Hypercholesterolemia (HeFH) and primary Hyperlipidemia .

Heterozygous Familial Hypercholesterolemia (HeFH)

primary Hyperlipidemia

Helps manage primary Hyperlipidemia

Hypercholesterolemia

Hyperlipidemia

Helps manage primary Hyperlipidemia

Dyslipidemias

Helps manage Mixed Dyslipidemias

Effectiveness

How Livalo Affects PatientsPitavastatin is a medication that helps to lower cholesterol levels. It reduces total cholesterol, low-density lipoprotein-cholesterol (LDL-C), non-high density lipoprotein-cholesterol (non-HDL-C), apolipoprotein B (apoB) and triglycerides (TG) in the blood, while increasing levels of high-density lipoprotein-cholesterol (HDL-C). Having too much LDL-C, low HDL-C and high TG in the blood increases the risk of developing atherosclerosis and other cardiovascular diseases. Taking statins, like pitavast

How Livalo works in the bodyPitavastatin is a drug that helps reduce cholesterol levels. It does this by blocking the enzyme that turns a molecule called HMG-CoA into cholesterol. This creates less cholesterol in the liver, which causes the body to absorb more of it from the blood. Pitavastatin has been found to have additional benefits, such as improving blood vessel function, reducing inflammation and oxidative stress, and preventing the formation of blood clots. It also binds to a type of white blood cell, which helps reduce inflammation.

When to interrupt dosage

The suggested dosage of Livalo is established by the determined condition, such as Hyperlipidemia, Hypercholesterolemia and Dyslipidemias. The amount of dosage shifts, in line with the method of administration (e.g. Tablet, film coated - Oral or Tablet, film coated) as detailed in the following table.

Condition

Dosage

Administration

Hyperlipidemia

2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral

Hypercholesterolemia

2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral

Dyslipidemias

2.0 mg, 4.0 mg, , 1.0 mg, 2.09 mg, 1.045 mg, 4.18 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral

Warnings

Livalo Contraindications

Condition

Risk Level

Notes

Breast Milk Production

Do Not Combine

Liver Diseases

Do Not Combine

Transaminases

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Livalo.

Common Livalo Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Pitavastatin.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Pitavastatin.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Pitavastatin.

Fluorouracil

Major

The metabolism of Fluorouracil can be decreased when combined with Pitavastatin.

Fosphenytoin

Major

The metabolism of Fosphenytoin can be decreased when combined with Pitavastatin.

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Livalo Novel Uses: Which Conditions Have a Clinical Trial Featuring Livalo?

Currently, 6 active clinical trials are exploring the potential of Livalo to ameliorate Dyslipidemias, Hyperlipidemia and Hypercholesterolemia.

Condition

Clinical Trials

Trial Phases

Hypercholesterolemia

2 Actively Recruiting

Phase 1, Phase 3

Hyperlipidemia

0 Actively Recruiting

Dyslipidemias

1 Actively Recruiting

Phase 2

Livalo Reviews: What are patients saying about Livalo?

5Patient Review

12/17/2019

Livalo for Combined High Blood Cholesterol and Triglyceride Level

I had tried a variety of different statins before, and they all made me feel awful-- body aches, malaise, pain in my limbs. It was terrible. My PA finally convinced me to try LIVALO, and I'm so glad she did! I've been on it for over a year now with no problems whatsoever. Plus, my levels are "awesome" according to my PA.

4.3Patient Review

9/4/2016

Livalo for High Cholesterol

I saw a significant decrease in my cholesterol levels, but have had some negative side effects like rashes, muscle cramps, and memory loss. I'm going to talk to my doctor about getting off of the medication.

3.7Patient Review

3/24/2017

Livalo for High Cholesterol

The side effects I experienced from taking livalo were so bad that I had to stop. My doctor said that the benefits of this drug are not worth the pain and suffering it caused me. All I want is to feel normal again.

3Patient Review

9/29/2018

Livalo for High Cholesterol

Livalo didn't give me the body aches that other statins did, but it did have some pretty severe anxiety and depression symptoms. I'm a 53 year old male, and these effects were really not worth it for me.

3Patient Review

4/8/2022

Livalo for Combined High Blood Cholesterol and Triglyceride Level

I saw some good results in the short-term, but they weren't worth the intense leg pain and weakness I experienced. I would rather make a drastic change to my diet than deal with this medication long-term.

View All Reviews

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Patient Q&A Section about livalo

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of Livalo?

"You may experience muscle pain, back pain, joint pain, pain in your arms and legs, diarrhea, constipation, skin rash, or headache."

Answered by AI

How does Livalo different from other statins?

"Livalo is a statin that reduces HMG-CoA. It is different from other statins because it has a cyclopropyl group on the base structure."

Answered by AI

What is the difference between Lipitor and Livalo?

"In a clinical trial comparing the effects of LIVALO and Lipitor in people with high cholesterol, it was shown that the 4-mg dose of LIVALO lowered LDL (bad) cholesterol just as much as Lipitor 20 mg, and that LIVALO 2 mg lowered it similarly to Lipitor 10 mg."

Answered by AI

What is special about Livalo?

"Livalo is a cholesterol-lowering medication for adults with high cholesterol. It helps to lower total cholesterol, "bad" cholesterol (LDL-C), triglycerides, and Apo B. It also raises "good" cholesterol (HDL-C)."

Answered by AI