Lasix

Nephrotic Syndrome, Ascites, Conn Syndrome + 11 more
Treatment
7 FDA approvals
20 Active Studies for Lasix

What is Lasix

FurosemideThe Generic name of this drug
Treatment SummaryFurosemide is a diuretic that helps the body get rid of excess water. It is prescribed for people with conditions like congestive heart failure, liver failure, renal failure, and high blood pressure. This drug works by blocking electrolyte reabsorption from the kidneys and increasing water excretion. It has a fast onset and short duration of action, making it suitable for both adults and children. It can be taken orally or intravenously or intramuscularly in emergencies or when the patient cannot take oral medication.
Lasixis the brand name
image of different drug pills on a surface
Lasix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lasix
Furosemide
1966
448

Approved as Treatment by the FDA

Furosemide, also known as Lasix, is approved by the FDA for 7 uses which include Congestive Heart Failure and Nephrotic Syndrome .
Congestive Heart Failure
Nephrotic Syndrome
Swollen feet or ankles
Hypertensive disease
Helps manage Mild to Moderate Hypertension
Cirrhosis
Chronic Kidney Disease (CKD)
Hypertensive disease
Used in combination with Hydrochlorothiazide / Losartan to help manage High Blood Pressure (Hypertension)

Effectiveness

How Lasix Affects PatientsFurosemide is used to help control high blood pressure, swelling, and kidney issues. It works by increasing the amount of salt and water that the kidneys remove from the body. After taking it orally, it should start to work within 1-1.5 hours and last 4-6 hours. If taken intravenously, it should start to work within 5 minutes and last up to 2 hours. If taken intramuscularly, it may take longer for the effects to kick in.
How Lasix works in the bodyFurosemide is a diuretic medication that stops the body from reabsorbing sodium and chloride in the kidneys. This results in increased urination, which helps to reduce the amount of water in the body. Furosemide also has direct effects on the blood vessels, causing them to widen and reducing the effect of other vasoconstrictors. This leads to reduced blood pressure and improved blood flow. Furosemide may also work by opening potassium channels in the blood vessels, leading to improved blood flow.

When to interrupt dosage

The suggested measure of Lasix is dictated by the identified illness, for example, kaliuretic diuretics, Cirrhosis and Congestive Heart Failure. The amount likewise fluctuates as indicated by the strategy of conveyance (e.g. Intramuscular; Intravenous or Solution - Oral) featured in the following table.
Condition
Dosage
Administration
Conn Syndrome
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Congestive Heart Failure
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Hypertensive disease
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Antihypertensive Treatment
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Cirrhosis
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Nephrotic Syndrome
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Swollen feet or ankles
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Hypertensive disease
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
kaliuretic diuretics
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Chronic Kidney Disease (CKD)
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Body Fluid Retention
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Ascites
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Acute Pulmonary Edema
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical
Congestive Heart Failure
, 80.0 mg, 40.0 mg, 20.0 mg, 10.0 mg/mL, 40.0 mg/mL, 20.0 mg/mL, 500.0 mg, 25.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, Injection - Intravenous, Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Solution, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intramuscular; Intravenous, Liquid - Oral, Liquid - Intravenous, Kit, Kit - Oral, Intramuscular; Intravascular, Injection - Intramuscular; Intravascular, Kit - Oral; Topical, Oral; Topical

Warnings

Lasix Contraindications
Condition
Risk Level
Notes
Anuria
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Furosemide may interact with Pulse Frequency
There are 20 known major drug interactions with Lasix.
Common Lasix Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Furosemide may increase the hypotensive activities of Amifostine.
Amikacin
Major
Furosemide may increase the ototoxic activities of Amikacin.
Apramycin
Major
Furosemide may increase the ototoxic activities of Apramycin.
Arbekacin
Major
Furosemide may increase the ototoxic activities of Arbekacin.
Bekanamycin
Major
Furosemide may increase the ototoxic activities of Bekanamycin.
Lasix Toxicity & Overdose RiskTaking too much of this drug can lead to dehydration, low blood volume, low blood pressure, imbalanced electrolytes, and abnormal heart rhythms. Symptoms of overdose include kidney failure, blood clots, confusion, and muscle weakness. In animals, the lowest toxic dose is 2600mg/kg when taken orally, 800mg/kg when administered intraperitoneally, and 4600mg/kg when given subcutaneously. In humans, the lowest toxic dose has been found to be 6250μg/kg in a female.
image of a doctor in a lab doing drug, clinical research

Lasix Novel Uses: Which Conditions Have a Clinical Trial Featuring Lasix?

693 trials are presently being conducted to assess the potential of Lasix in controlling Kidney Diseases, Oedema and Congestive Heart Failure.
Condition
Clinical Trials
Trial Phases
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Congestive Heart Failure
312 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1, Phase 4
Hypertensive disease
1 Actively Recruiting
Not Applicable
Acute Pulmonary Edema
0 Actively Recruiting
Nephrotic Syndrome
11 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Body Fluid Retention
0 Actively Recruiting
kaliuretic diuretics
0 Actively Recruiting
Ascites
10 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2
Antihypertensive Treatment
0 Actively Recruiting
Congestive Heart Failure
23 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1
Swollen feet or ankles
40 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Conn Syndrome
7 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Chronic Kidney Disease (CKD)
245 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Cirrhosis
50 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1

Lasix Reviews: What are patients saying about Lasix?

5Patient Review
5/24/2016
Lasix for Visible Water Retention
Lasix has helped me a lot. I can finally wear shoes that previously were too uncomfortable, and don't have to worry about my rings cutting off circulation anymore. The only downside is that it's made my blood sugar levels go up, which isn't ideal.
5Patient Review
7/31/2016
Lasix for Visible Water Retention
I was struggling with swollen ankles and feet, so I decided to give this medication a try. I was really surprised when I woke up the next morning and my swelling had gone down by half! I'll definitely continue taking it, even though it does make me have to go to the bathroom more often.
5Patient Review
6/3/2014
Lasix for High Blood Pressure
Lasix makes me nauseous and tired.
5Patient Review
6/2/2014
Lasix for Visible Water Retention
4.7Patient Review
4/6/2016
Lasix for Accumulation of Fluid Resulting from Chronic Heart Failure
Works slowly, but does the job.
4.3Patient Review
7/1/2016
Lasix for Visible Water Retention
I was originally prescribed this when I had cellulitis and it worked really well. My doctor told me I could stop taking it, but after a month off the medication my ankle started swelling up again and I wasn't able to walk very well. So, I started back on the medication and I'm doing much better now.
4Patient Review
11/3/2016
Lasix for Visible Water Retention
I've been taking this drug for a few months and have experienced some pretty unfortunate side effects, like dry mouth and bleeding gums. I have also lost weight on the medication, which isn't ideal. However, the benefits of the drug outweigh the negatives for me.
3.7Patient Review
6/22/2015
Lasix for Visible Water Retention
Lasix was great in that it stopped the swelling in my lower extremities. However, I developed muscle cramps all over my body. Once I stopped taking the medication, the cramping went away but the swelling started again. I'm going to ask my doctor if there's a way to take Lasix every other day or every third day instead of daily. Has anyone else tried this method?
3.3Patient Review
4/3/2016
Lasix for Visible Water Retention
Slowed my pulse down to 29, increased my depression, and caused a major headache that lasted for weeks.
3Patient Review
6/22/2014
Lasix for Accumulation of Fluid Resulting from Chronic Heart Failure
It took some time to get the dosage right, but now that I'm taking 80mg three times a day, the swelling in my ankles and legs has gone down. Plus, I've lost 50 pounds as a result!
3Patient Review
3/27/2015
Lasix for Visible Water Retention
I experienced a lot of sweating, thirst, and shortness of breath. I also felt lightheaded and faint at times.
3Patient Review
2/20/2022
Lasix for Fluid in the Lungs due to Chronic Heart Failure
I've had diarrhea and blurry vision for a week now.
2.7Patient Review
2/23/2014
Lasix for Visible Water Retention
2.3Patient Review
7/15/2018
Lasix for Accumulation of Fluid Resulting from Chronic Heart Failure
My 78 year old father has been taking Lasix for close to two weeks now and is starting to experience some nasty side effects, such as increased thirst, trouble sleeping, unsteadiness, and hearing loss.
2Patient Review
9/16/2015
Lasix for High Blood Pressure
I was taking this medication a few years ago to help with water retention, but I'm seeing similar symptoms again. It's hard to tell if it's the medicine or something else I'm taking, but either way, it's not effective for me.
2Patient Review
5/5/2022
Lasix for Visible Water Retention
I took lasix for swelling in my ankles. I couldn't take it very long because it caused a severe gout attack in my left knee to the point I could barely walk. Lasix can cause a gout flare up without raising your uric acid level
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about lasix

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Should you drink a lot of water when taking Lasix?

"Be sure to drink plenty of water while exercising and in hot weather when taking Lasix, especially if you sweat a lot. Not drinking enough water while taking Lasix can cause you to feel faint or lightheaded, or even sick, due to a sudden drop in blood pressure from dehydration."

Answered by AI

What is the drug Lasix used for?

"Furosemide is used to reduce extra fluid in the body by increasing the amount of urine you make."

Answered by AI

What are the side effects of taking Lasix?

"change in the amount of urine,, headache

The text lists the following symptoms: increased urination, thirst, muscle cramps, itching or rash, weakness, dizziness, spinning sensation, diarrhea, change in the amount of urine, headache."

Answered by AI

Is Lasix a water pill?

"Furosemide helps the kidneys get rid of extra water and electrolytes, which can help with swelling and lower blood pressure."

Answered by AI

Clinical Trials for Lasix

Have you considered Lasix clinical trials? We made a collection of clinical trials featuring Lasix, we think they might fit your search criteria.
Have you considered Lasix clinical trials? We made a collection of clinical trials featuring Lasix, we think they might fit your search criteria.
Have you considered Lasix clinical trials? We made a collection of clinical trials featuring Lasix, we think they might fit your search criteria.
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