Machine Preservation for Kidney Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
The primary purpose of this study is to evaluate the safety and efficacy of ex vivo machine perfusion with staged implantation of kidney allografts during combined heart/kidney transplantation.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is machine perfusion for kidney preservation safe for humans?
How is the treatment of planned delayed implantation of kidney allograft with ex vivo machine perfusion kidney preservation different from other treatments for kidney disease?
What data supports the effectiveness of the treatment Planned delayed implantation of kidney allograft with ex vivo machine perfusion kidney preservation?
Who Is on the Research Team?
Justin A Steggerda, M.D.
Principal Investigator
Cedars-Sinai Medical Center
Are You a Good Fit for This Trial?
This trial is for patients with severe heart and kidney conditions who need both a heart and kidney transplant. They should be stable enough to undergo staged surgeries, first receiving the heart then the kidney after some time.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Heart Transplantation
Participants undergo heart transplantation as part of the combined heart/kidney transplantation procedure
Delayed Kidney Transplantation
Participants receive delayed kidney transplantation with hypothermic oxygenated machine perfusion (HOPE) for kidney preservation
Follow-up
Participants are monitored for safety and effectiveness after transplantation, including monitoring for delayed graft function and adverse events
What Are the Treatments Tested in This Trial?
Interventions
- Planned delayed implantation of kidney allograft with ex vivo machine perfusion kidney preservation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Cedars-Sinai Medical Center
Lead Sponsor