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What is Irinotecan Hydrochloride
Approved as Treatment by the FDA
Irinotecan, commonly known as Camptosar, is approved by the FDA for 4 uses which include Metastatic Colorectal Carcinoma and refractory, metastatic Pancreatic adenocarcinoma .Effectiveness
When to interrupt dosage
The measure of Irinotecan Hydrochloride is contingent upon the determined malady, including Ovarian Cancer, Pancreatic Cancer and Stomach Cancer. The dosage may differ, due to the method of delivery (e.g. Injection, solution or Injection) detailed in the table beneath.Warnings
There are 20 known major drug interactions with Irinotecan Hydrochloride.Irinotecan Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Irinotecan Hydrochloride?
1157 active studies are examining the potential of Irinotecan Hydrochloride to treat Esophageal Cancer, Glioblastoma and Metastatic Colorectal Carcinoma.Irinotecan Hydrochloride Reviews: What are patients saying about Irinotecan Hydrochloride?
Patient Q&A Section about irinotecan hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are indications for irinotecan HCL?
"Irinotecan Hydrochloride medac can be used in combination with 5-fluorouracil, folinic acid, and bevacizumab to treat metastatic colon or rectal cancer."
Is irinotecan a chemotherapy drug?
"Irinotecan is a chemotherapy drug used to treat cancer, typically bowel cancer. It is also known by its brand name Campto."
What is the mechanism of action of irinotecan?
"Irinotecan inhibits topoisomerase I from performing its natural function. Without topoisomerase I, the DNA strand cannot be properly religated. This interferes with the moving replication fork, and causes replicative arrest and double-stranded DNA breaks, which are lethal."
What is irinotecan used for?
"Irinotecan injection is given alongside other medication (for example, 5-fluorouracil, leucovorin) to treat patients with metastatic cancer (a cancer that has already spread) of the colon or rectum."