IMD10 + Chemotherapy for Pancreatic Cancer

Not yet recruiting at 4 trial locations
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: IMGT Co., Ltd.
Must be taking: Chemotherapy
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this Interventional clinical trial is to evaluate safety and efficacy of 'IMD10 (focused ultrasound)' in the treatment of borderline resectable pancreatic cancer or locally advanced pancreatic cancer.

Are You a Good Fit for This Trial?

This trial is for adults aged 18-85 with borderline resectable or locally advanced pancreatic cancer, confirmed by pathology. Participants must have a measurable lesion, be in good physical condition (ECOG status 0 or 1), and have certain blood and organ function levels. They should not be pregnant or breastfeeding and must agree to use contraception if of childbearing potential.

Inclusion Criteria

I am between 18 and 85 years old.
My diagnosis of pancreatic cancer is confirmed by lab tests on tissue or fluid samples.
My pancreatic cancer is classified as borderline resectable or locally advanced.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive a chemotherapy regimen with or without IMD10 (focused ultrasound)

12 weeks
Weekly visits for chemotherapy administration

Follow-up

Participants are monitored for safety and survival until the end of the study

Until end of study

What Are the Treatments Tested in This Trial?

Interventions

  • IMD10

Trial Overview

The trial is testing the safety and effectiveness of IMD10 (focused ultrasound) combined with a chemotherapy regimen including irinotecan hydrochloride, oxaliplatin, fluorouracil (5-FU), and leucovorin in treating pancreatic cancer that's on the verge of being operable or has spread locally.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Experimental groupExperimental Treatment2 Interventions
Group II: Control groupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

IMGT Co., Ltd.

Lead Sponsor