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What is Innopran Xl
PropranololThe Generic name of this drug
Treatment SummaryPropranolol is a drug used to treat high blood pressure and other conditions. It is composed of two different types of molecules, with the S(-) molecule being the most effective at binding to receptors in the body. Propranolol was approved by the FDA in 1967 and is generally considered safe and effective for treating hypertension.
Inderalis the brand name
Innopran Xl Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inderal
Propranolol
1967
471
Approved as Treatment by the FDA
Propranolol, also known as Inderal, is approved by the FDA for 3 uses including Hypertensive disease and Tremor, Essential .Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide
Tremor, Essential
Helps manage Tremor, Essential
Obstructive Hypertrophic Cardiomyopathy
Effectiveness
How Innopran Xl Affects PatientsPropranolol is a drug used to treat high blood pressure. It is usually given once or twice a day and has long-lasting effects. If patients stop taking propranolol suddenly, they may have a greater chance of having chest pain or a heart attack.
How Innopran Xl works in the bodyPropranolol blocks certain receptors in the body that cause blood vessels to widen. This can reduce the growth of new blood vessels, cause cell death, and lessen the effects of a hormone system that helps control blood pressure.
When to interrupt dosage
The suggested measure of Innopran Xl is contingent upon the confirmed disorder, for example, Catecholamines, Hypertensive disease and Hemangiomas. The measurement of dosage fluctuates, in line with the delivery strategy (e.g. Solution - Oral or Capsule, extended release - Oral) noted in the table underneath.Condition
Dosage
Administration
Catecholamines
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Chest Pain
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Coronary Artery Atherosclerosis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tremor, Essential
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Atrial Fibrillation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Akathisia caused by antipsychotic use
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Obstructive Hypertrophic Cardiomyopathy
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Heart Attack
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Performance Anxiety
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Pheochromocytomas
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Rapid Ventricular Response
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Ventricular Tachycardia
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Thyroid Crisis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Cardiovascular Mortality
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Myocardial Infarction
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tachyarrhythmia caused by Digitalis intoxication
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Gastroesophageal variceal hemorrhage prophylaxis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hemangiomas
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Supraventricular Arrhythmias
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Warnings
Innopran Xl has fifteen contraindications, so it should not be taken in cases involving the conditions detailed in the table below.Innopran Xl ContraindicationsCondition
Risk Level
Notes
Heart Decompensation
Do Not Combine
Bronchospasm
Do Not Combine
Bronchial Asthma
Do Not Combine
Infants Weighing <2kg
Do Not Combine
Low Blood Pressure
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Asthma
Do Not Combine
Pheochromocytomas
Do Not Combine
second or third degree AV block
Do Not Combine
Slow Heart Rate
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Heart Decompensation
Do Not Combine
Prematurity
Do Not Combine
Sinus Bradycardia
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Propranolol may interact with Pulse Frequency
Common Innopran Xl Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propranolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Propranolol.
Abediterol
Major
Propranolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Propranolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Propranolol.
Innopran Xl Toxicity & Overdose RiskOverdosing on propranolol can lead to low blood pressure, seizures due to low blood sugar, restlessness, and lack of sleep. Those with asthma may experience trouble breathing. To treat propranolol overdose, vital signs and mental status should be monitored, intravenous fluids should be administered to treat hypotension, atropine and isoproterenol should be used to treat bradycardia, glucagon should be administered if fluids are ineffective, and catecholamines may be necessary. Dialysis is not useful for propranolol overdoses because the drug is highly protein bound.
Innopran Xl Novel Uses: Which Conditions Have a Clinical Trial Featuring Innopran Xl?
249 active trials are currently assessing the potential of Innopran XL in providing relief from Migraine, Catecholamine-induced symptoms and Hypertensive Diseases.Condition
Clinical Trials
Trial Phases
Catecholamines
0 Actively Recruiting
Hemangiomas
0 Actively Recruiting
prophylaxis of migraine headaches
0 Actively Recruiting
Coronary Artery Atherosclerosis
2 Actively Recruiting
Not Applicable, Phase 4
Ventricular Tachycardia
14 Actively Recruiting
Phase 3, Phase 4, Not Applicable, Phase 2, Early Phase 1
Gastroesophageal variceal hemorrhage prophylaxis
0 Actively Recruiting
Akathisia caused by antipsychotic use
0 Actively Recruiting
Performance Anxiety
0 Actively Recruiting
Cardiovascular Mortality
0 Actively Recruiting
Thyroid Crisis
0 Actively Recruiting
Heart Attack
53 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Atrial Fibrillation
146 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Migraine
52 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Proliferating Infantile Hemangioma
0 Actively Recruiting
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Thyrotoxicosis
0 Actively Recruiting
Supraventricular Arrhythmias
0 Actively Recruiting
Tachyarrhythmia caused by Digitalis intoxication
0 Actively Recruiting
Pheochromocytomas
0 Actively Recruiting
Chest Pain
6 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
Innopran Xl Reviews: What are patients saying about Innopran Xl?
5Patient Review
1/12/2010 I've been very pleased with the results of this medication for migraines. I just have to make sure to take it every day, and it works wonders. I started off taking one 80mg pill per day, but now take two a day (160mg). The only downside is that I have to split the doses up between morning and evening because 160mg at once was too much for me. So long as you can get through the side effects and find the right dosage, this drug is great! Just be sure to work closely with your doctor.
5Patient Review
2/1/2012 I'm trying to determine which medication I'm on is causing me to have early onset dementia symptoms. I've been on this particular one the longest, so it's possible that it's the culprit.
5Patient Review
1/8/2009 I didn't experience any negative side effects, which was great. This medication lessened the severity of my migraines but didn't get rid of them entirely. I only had to take one pill a day, which was very convenient.
5Patient Review
12/14/20075Patient Review
10/30/2008 This medicine has lowered my blood pressure significantly. I was very relieved when my doctor prescribed it.
5Patient Review
5/9/2012 For years, this treatment has helped to keep my blood pressure stable. Additionally, it almost completely stopped my migraines from occurring.
4.7Patient Review
11/26/2009 I'm not convinced that this medication is actually effective for migraines or blood pressure. I saw no improvement, and possibly even a worsening of symptoms, until another doctor added amlodipine to my treatment regimen.
4.7Patient Review
8/28/20083.7Patient Review
10/20/2008 We tried a lot of different medications when we finally discovered that my pain was caused by migraines. None of them worked, and some even made me feel worse. But then we found a medication that did the trick. It's more than I wanted to take, at two pills per day at 80mg, but it helped me immensely. Now I can function every day with only occasional pressure. Good luck!
3.7Patient Review
12/26/2008 This is the only drug that has worked for me. In the past, my irregular heartbeat would last for 4-6 hours and I was unable to do anything during that time. This would happen at least 3 times a week. I don't know if I'm having a hot flash or the excessive sweating is caused by the InnoPran XL.
3.3Patient Review
1/29/2013 I'm changing from this medicine because the price just got raised five times.
3Patient Review
3/5/2009 I was getting migraines at least twice a week, so I went to the doctor. He prescribed this medication and naproxen for me. I'm really pleased with both of them; I only get migraines about once a month now, and that's usually because I forget to take the innopran.
3Patient Review
4/5/2011 I unfortunately experienced tremors as a result of taking this medication. My primary care doctor then had to prescribe me an additional medication to counteract the side effect. In my opinion, it's not worth the risk when there are other options out there.
Patient Q&A Section about innopran xl
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Who makes InnoPran XL?
"This is the package insert for InnoPran XL, a medication used to treat high blood pressure, angina, and other heart conditions."
Answered by AI
What are side effects of propranolol?
"Drowsiness, lightheadedness, or fatigue may occur as your body adjusts to the medication. Nausea/vomiting, stomach pain, vision changes, difficulty sleeping, and unusual dreams may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly."
Answered by AI
What is the drug propranolol used for?
"Propranolol is a beta blocker that is used to treat heart problems, help with anxiety, and prevent migraines."
Answered by AI
What is InnoPran XL used for?
"InnoPran XL is a prescription medication that belongs to a class of drugs known as beta blockers. These drugs are commonly used to treat high blood pressure by reducing the amount of work that the heart has to do. This in turn lowers blood pressure and can reduce the risk of strokes and heart attacks."
Answered by AI