Innopran Xl

Thyroid Crisis, Atrial Fibrillation, Migraine + 23 more
Treatment
5 FDA approvals
20 Active Studies for Innopran Xl

What is Innopran Xl

PropranololThe Generic name of this drug
Treatment SummaryPropranolol is a drug used to treat high blood pressure and other conditions. It is composed of two different types of molecules, with the S(-) molecule being the most effective at binding to receptors in the body. Propranolol was approved by the FDA in 1967 and is generally considered safe and effective for treating hypertension.
Inderalis the brand name
image of different drug pills on a surface
Innopran Xl Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inderal
Propranolol
1967
471

Approved as Treatment by the FDA

Propranolol, also known as Inderal, is approved by the FDA for 5 uses including Obstructive Hypertrophic Cardiomyopathy and Tremor, Essential .
Obstructive Hypertrophic Cardiomyopathy
Tremor, Essential
Helps manage Tremor, Essential
Essential Tremor
Helps manage Tremor, Essential
Cardiomyopathy, Hypertrophic
Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide

Effectiveness

How Innopran Xl Affects PatientsPropranolol is a drug used to treat high blood pressure. It is usually given once or twice a day and has long-lasting effects. If patients stop taking propranolol suddenly, they may have a greater chance of having chest pain or a heart attack.
How Innopran Xl works in the bodyPropranolol blocks certain receptors in the body that cause blood vessels to widen. This can reduce the growth of new blood vessels, cause cell death, and lessen the effects of a hormone system that helps control blood pressure.

When to interrupt dosage

The suggested measure of Innopran Xl is contingent upon the confirmed disorder, for example, Catecholamines, Hypertensive disease and Hemangiomas. The measurement of dosage fluctuates, in line with the delivery strategy (e.g. Solution - Oral or Capsule, extended release - Oral) noted in the table underneath.
Condition
Dosage
Administration
Heart Attack
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Adrenergic Alpha-Antagonists
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tachyarrhythmia caused by Digitalis intoxication
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Psychomotor Agitation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tremor
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Thyrotoxicosis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Chest Pain
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Supraventricular Arrhythmias
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hemangioma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Cardiomyopathy, Hypertrophic
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Proliferating Infantile Hemangioma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hypertensive disease
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Performance Anxiety
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Pheochromocytoma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Ventricular Tachycardia
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Gastroesophageal variceal hemorrhage prophylaxis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Catecholamines
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine Disorders
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Atrial Fibrillation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Warnings

Innopran Xl has fifteen contraindications, so it should not be taken in cases involving the conditions detailed in the table below.Innopran Xl Contraindications
Condition
Risk Level
Notes
Heart Decompensation
Do Not Combine
Bronchial Spasm
Do Not Combine
Asthma
Do Not Combine
Infants Weighing <2kg
Do Not Combine
Low Blood Pressure
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Asthma
Do Not Combine
Pheochromocytoma
Do Not Combine
Atrioventricular Block
Do Not Combine
Slow Heart Rate
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Heart Decompensation
Do Not Combine
Prematurity
Do Not Combine
Sinus Bradycardia
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Propranolol may interact with Pulse Frequency
There are 20 known major drug interactions with Innopran Xl.
Common Innopran Xl Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propranolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Propranolol.
Abediterol
Major
Propranolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Propranolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Propranolol.
Innopran Xl Toxicity & Overdose RiskOverdosing on propranolol can lead to low blood pressure, seizures due to low blood sugar, restlessness, and lack of sleep. Those with asthma may experience trouble breathing. To treat propranolol overdose, vital signs and mental status should be monitored, intravenous fluids should be administered to treat hypotension, atropine and isoproterenol should be used to treat bradycardia, glucagon should be administered if fluids are ineffective, and catecholamines may be necessary. Dialysis is not useful for propranolol overdoses because the drug is highly protein bound.
image of a doctor in a lab doing drug, clinical research

Innopran Xl Novel Uses: Which Conditions Have a Clinical Trial Featuring Innopran Xl?

249 active trials are currently assessing the potential of Innopran XL in providing relief from Migraine, Catecholamine-induced symptoms and Hypertensive Diseases.
Condition
Clinical Trials
Trial Phases
Atrial Fibrillation
96 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Coronary Artery Disease
1 Actively Recruiting
Not Applicable
Chest Pain
2 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Adrenergic Alpha-Antagonists
0 Actively Recruiting
Migraine
54 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Hemangioma
0 Actively Recruiting
Gastroesophageal variceal hemorrhage prophylaxis
0 Actively Recruiting
Migraine Disorders
1 Actively Recruiting
Phase 3
Catecholamines
0 Actively Recruiting
Thyroid Crisis
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Pheochromocytoma
0 Actively Recruiting
Thyrotoxicosis
0 Actively Recruiting
Cardiovascular Mortality
0 Actively Recruiting
Myocardial Infarction
0 Actively Recruiting
Tremor
0 Actively Recruiting
Cardiomyopathy, Hypertrophic
0 Actively Recruiting
Proliferating Infantile Hemangioma
0 Actively Recruiting
Psychomotor Agitation
0 Actively Recruiting

Innopran Xl Reviews: What are patients saying about Innopran Xl?

5Patient Review
1/12/2010
Innopran Xl for Migraine Prevention
I've been very pleased with the results of this medication for migraines. I just have to make sure to take it every day, and it works wonders. I started off taking one 80mg pill per day, but now take two a day (160mg). The only downside is that I have to split the doses up between morning and evening because 160mg at once was too much for me. So long as you can get through the side effects and find the right dosage, this drug is great! Just be sure to work closely with your doctor.
5Patient Review
2/1/2012
Innopran Xl for High Blood Pressure
I'm trying to determine which medication I'm on is causing me to have early onset dementia symptoms. I've been on this particular one the longest, so it's possible that it's the culprit.
5Patient Review
1/8/2009
Innopran Xl for Migraine Prevention
I didn't experience any negative side effects, which was great. This medication lessened the severity of my migraines but didn't get rid of them entirely. I only had to take one pill a day, which was very convenient.
5Patient Review
12/14/2007
Innopran Xl for High Blood Pressure
5Patient Review
10/30/2008
Innopran Xl for Essential Tremor
This medicine has lowered my blood pressure significantly. I was very relieved when my doctor prescribed it.
View All Reviews
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Patient Q&A Section about innopran xl

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who makes InnoPran XL?

"This is the package insert for InnoPran XL, a medication used to treat high blood pressure, angina, and other heart conditions."

Answered by AI

What are side effects of propranolol?

"Drowsiness, lightheadedness, or fatigue may occur as your body adjusts to the medication. Nausea/vomiting, stomach pain, vision changes, difficulty sleeping, and unusual dreams may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly."

Answered by AI

What is the drug propranolol used for?

"Propranolol is a beta blocker that is used to treat heart problems, help with anxiety, and prevent migraines."

Answered by AI

What is InnoPran XL used for?

"InnoPran XL is a prescription medication that belongs to a class of drugs known as beta blockers. These drugs are commonly used to treat high blood pressure by reducing the amount of work that the heart has to do. This in turn lowers blood pressure and can reduce the risk of strokes and heart attacks."

Answered by AI

Clinical Trials for Innopran Xl

Have you considered Innopran Xl clinical trials? We made a collection of clinical trials featuring Innopran Xl, we think they might fit your search criteria.
Have you considered Innopran Xl clinical trials? We made a collection of clinical trials featuring Innopran Xl, we think they might fit your search criteria.
Have you considered Innopran Xl clinical trials? We made a collection of clinical trials featuring Innopran Xl, we think they might fit your search criteria.