Hydrocortisone And Acetic Acid

Infection, Communicable Diseases, Urinary Bladder + 2 more

Treatment

5 FDA approvals

5 Active Studies for Hydrocortisone And Acetic Acid

What is Hydrocortisone And Acetic Acid

Acetic acid

The Generic name of this drug

Treatment Summary

Hydrocortisone, also known as cortisol, is a hormone made by the adrenal glands. It is used to treat conditions caused by inflammation, the immune system, or tumors. Hydrocortisone was discovered in the 1930s and was approved by the FDA in 1952.

Acetic Acid

is the brand name

image of different drug pills on a surface

Hydrocortisone And Acetic Acid Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Acetic Acid

Acetic acid

1979

33

Approved as Treatment by the FDA

Acetic acid, otherwise called Acetic Acid, is approved by the FDA for 5 uses which include External ear infection NOS and Urinary Bladder .

External ear infection NOS

Used to treat External ear infection NOS in combination with Acetic acid

Urinary Bladder

Urethral Catheters

Infection

Communicable Diseases

Used to treat External ear infection NOS in combination with Acetic acid

Effectiveness

How Hydrocortisone And Acetic Acid Affects Patients

Hydrocortisone works by attaching to special receptors in the body, blocking chemicals that cause inflammation. This drug is usually considered safe and can be taken for a moderate length of time. However, people should stop taking it if they experience any irritation or allergic reactions.

How Hydrocortisone And Acetic Acid works in the body

Corticosteroids reduce inflammation by decreasing the widening of blood vessels, slowing down the movement of white blood cells, and altering gene expression. Lower doses of corticosteroids stop inflammation, while higher doses reduce the body's immune response. When taken at high doses over a long period of time, corticosteroids can also raise sodium levels and lower potassium levels.

When to interrupt dosage

The quantity of Hydrocortisone And Acetic Acid is contingent upon the diagnosed affliction, including Ophthalmia, Sympathetic, Drug Allergy and Sarcoidosis. The dose likewise alters as per the system of delivery (e.g. Topical or Auricular (otic)) delineated in the following table.

Condition

Dosage

Administration

Communicable Diseases

, 20.75 mg/mL, 20.65 mg/mL, 2.5 mg/mL, 24.1 mg/mL, 0.02 mL/mL, 0.009 mg/mg, 20.8 mg/mL, 25.0 mg/mL, 2.0 mg/mL, 0.02 mg/mL, 1.5 %, 0.9 mg/mL, 20.0 mg/mL, 0.0092 mg/mg, 0.1 mg/mL, 10.81 mg/mL, 10.8 mg/mL, 8.11 mg/mL, 8.846 mg/mL, 5.41 mg/mL, 6.64 mg/mL, 5.28 mg/mL, 6.635 mg/mL, 36.0 mg/mL, 6.31 mg/mL, 5.4 mg/mL, 8.8 mg/mL, 8.85 mg/mL, 6.82 mg/mL, 6.305 mg/mL, 6.756 mg/mL, 8.1 mg/mL, 8.9 mg/mL, 8.847 mg/mL, 6.6349 mg/mL, 6.3053 mg/mL, 8.107 mg/mL, 0.004 meq/mL, 15.0 mg/mL

Solution, , Solution - Auricular (otic), Auricular (otic), Irrigation, Irrigant - Irrigation, Irrigant, Vaginal, Jelly, Jelly - Vaginal, Liquid, Hemodialysis, Solution - Hemodialysis, Liquid - Hemodialysis, Solution / drops, Topical, Gel - Topical, Gel - Vaginal, Gel, Solution / drops - Auricular (otic), Solution - Topical, Liquid - Topical

Infection

, 20.75 mg/mL, 20.65 mg/mL, 2.5 mg/mL, 24.1 mg/mL, 0.02 mL/mL, 0.009 mg/mg, 20.8 mg/mL, 25.0 mg/mL, 2.0 mg/mL, 0.02 mg/mL, 1.5 %, 0.9 mg/mL, 20.0 mg/mL, 0.0092 mg/mg, 0.1 mg/mL, 10.81 mg/mL, 10.8 mg/mL, 8.11 mg/mL, 8.846 mg/mL, 5.41 mg/mL, 6.64 mg/mL, 5.28 mg/mL, 6.635 mg/mL, 36.0 mg/mL, 6.31 mg/mL, 5.4 mg/mL, 8.8 mg/mL, 8.85 mg/mL, 6.82 mg/mL, 6.305 mg/mL, 6.756 mg/mL, 8.1 mg/mL, 8.9 mg/mL, 8.847 mg/mL, 6.6349 mg/mL, 6.3053 mg/mL, 8.107 mg/mL, 0.004 meq/mL, 15.0 mg/mL

Solution, , Solution - Auricular (otic), Auricular (otic), Irrigation, Irrigant - Irrigation, Irrigant, Vaginal, Jelly, Jelly - Vaginal, Liquid, Hemodialysis, Solution - Hemodialysis, Liquid - Hemodialysis, Solution / drops, Topical, Gel - Topical, Gel - Vaginal, Gel, Solution / drops - Auricular (otic), Solution - Topical, Liquid - Topical

Urinary Bladder

, 20.75 mg/mL, 20.65 mg/mL, 2.5 mg/mL, 24.1 mg/mL, 0.02 mL/mL, 0.009 mg/mg, 20.8 mg/mL, 25.0 mg/mL, 2.0 mg/mL, 0.02 mg/mL, 1.5 %, 0.9 mg/mL, 20.0 mg/mL, 0.0092 mg/mg, 0.1 mg/mL, 10.81 mg/mL, 10.8 mg/mL, 8.11 mg/mL, 8.846 mg/mL, 5.41 mg/mL, 6.64 mg/mL, 5.28 mg/mL, 6.635 mg/mL, 36.0 mg/mL, 6.31 mg/mL, 5.4 mg/mL, 8.8 mg/mL, 8.85 mg/mL, 6.82 mg/mL, 6.305 mg/mL, 6.756 mg/mL, 8.1 mg/mL, 8.9 mg/mL, 8.847 mg/mL, 6.6349 mg/mL, 6.3053 mg/mL, 8.107 mg/mL, 0.004 meq/mL, 15.0 mg/mL

Solution, , Solution - Auricular (otic), Auricular (otic), Irrigation, Irrigant - Irrigation, Irrigant, Vaginal, Jelly, Jelly - Vaginal, Liquid, Hemodialysis, Solution - Hemodialysis, Liquid - Hemodialysis, Solution / drops, Topical, Gel - Topical, Gel - Vaginal, Gel, Solution / drops - Auricular (otic), Solution - Topical, Liquid - Topical

Otitis Externa

, 20.75 mg/mL, 20.65 mg/mL, 2.5 mg/mL, 24.1 mg/mL, 0.02 mL/mL, 0.009 mg/mg, 20.8 mg/mL, 25.0 mg/mL, 2.0 mg/mL, 0.02 mg/mL, 1.5 %, 0.9 mg/mL, 20.0 mg/mL, 0.0092 mg/mg, 0.1 mg/mL, 10.81 mg/mL, 10.8 mg/mL, 8.11 mg/mL, 8.846 mg/mL, 5.41 mg/mL, 6.64 mg/mL, 5.28 mg/mL, 6.635 mg/mL, 36.0 mg/mL, 6.31 mg/mL, 5.4 mg/mL, 8.8 mg/mL, 8.85 mg/mL, 6.82 mg/mL, 6.305 mg/mL, 6.756 mg/mL, 8.1 mg/mL, 8.9 mg/mL, 8.847 mg/mL, 6.6349 mg/mL, 6.3053 mg/mL, 8.107 mg/mL, 0.004 meq/mL, 15.0 mg/mL

Solution, , Solution - Auricular (otic), Auricular (otic), Irrigation, Irrigant - Irrigation, Irrigant, Vaginal, Jelly, Jelly - Vaginal, Liquid, Hemodialysis, Solution - Hemodialysis, Liquid - Hemodialysis, Solution / drops, Topical, Gel - Topical, Gel - Vaginal, Gel, Solution / drops - Auricular (otic), Solution - Topical, Liquid - Topical

Urethral Catheters

, 20.75 mg/mL, 20.65 mg/mL, 2.5 mg/mL, 24.1 mg/mL, 0.02 mL/mL, 0.009 mg/mg, 20.8 mg/mL, 25.0 mg/mL, 2.0 mg/mL, 0.02 mg/mL, 1.5 %, 0.9 mg/mL, 20.0 mg/mL, 0.0092 mg/mg, 0.1 mg/mL, 10.81 mg/mL, 10.8 mg/mL, 8.11 mg/mL, 8.846 mg/mL, 5.41 mg/mL, 6.64 mg/mL, 5.28 mg/mL, 6.635 mg/mL, 36.0 mg/mL, 6.31 mg/mL, 5.4 mg/mL, 8.8 mg/mL, 8.85 mg/mL, 6.82 mg/mL, 6.305 mg/mL, 6.756 mg/mL, 8.1 mg/mL, 8.9 mg/mL, 8.847 mg/mL, 6.6349 mg/mL, 6.3053 mg/mL, 8.107 mg/mL, 0.004 meq/mL, 15.0 mg/mL

Solution, , Solution - Auricular (otic), Auricular (otic), Irrigation, Irrigant - Irrigation, Irrigant, Vaginal, Jelly, Jelly - Vaginal, Liquid, Hemodialysis, Solution - Hemodialysis, Liquid - Hemodialysis, Solution / drops, Topical, Gel - Topical, Gel - Vaginal, Gel, Solution / drops - Auricular (otic), Solution - Topical, Liquid - Topical

Warnings

Hydrocortisone And Acetic Acid has fourteen contraindications, so it should be avoided if you are experiencing any of the conditions noted in the following table.

Hydrocortisone And Acetic Acid Contraindications

Condition

Risk Level

Notes

use during transurethral surgical procedures

Do Not Combine

Tympanic Membrane Perforation

Do Not Combine

There are 18 known major drug interactions with Hydrocortisone And Acetic Acid.

Common Hydrocortisone And Acetic Acid Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Acetic acid.

Typhoid vaccine

Minor

The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Acetic acid.

(R)-warfarin

Moderate

The risk or severity of bleeding can be increased when Acetic acid is combined with (R)-warfarin.

(S)-Warfarin

Moderate

The risk or severity of bleeding can be increased when Acetic acid is combined with (S)-Warfarin.

4-hydroxycoumarin

Moderate

The risk or severity of bleeding can be increased when Acetic acid is combined with 4-hydroxycoumarin.

Hydrocortisone And Acetic Acid Toxicity & Overdose Risk

Taking too much glucocorticoids over a long period of time can cause cataracts, glaucoma, high blood pressure, water retention, high cholesterol, ulcers, pancreatitis, muscle weakness, mood changes, skin thinning, allergies, acne, excessive hair growth, decreased resistance to infection, round face, high blood sugar, low calcium or phosphorus levels, acidosis, stunted growth, and reduced functioning of the adrenal glands. In the case of an overdose, the dose should be adjusted or stopped, and supportive treatment should be provided.

image of a doctor in a lab doing drug, clinical research

Hydrocortisone And Acetic Acid Novel Uses: Which Conditions Have a Clinical Trial Featuring Hydrocortisone And Acetic Acid?

525 active studies are currently being conducted to investigate the potential of Hydrocortisone And Acetic Acid in alleviating Ulcerative Colitis, Inflammatory reactions and Trichinosis.

Condition

Clinical Trials

Trial Phases

Urinary Bladder

0 Actively Recruiting

Otitis Externa

0 Actively Recruiting

Infection

6 Actively Recruiting

Not Applicable, Phase 1

Communicable Diseases

0 Actively Recruiting

Urethral Catheters

0 Actively Recruiting

Patient Q&A Section about hydrocortisone and acetic acid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does acetic acid do for ears?

"The text explains that acetic acid is effective in treating an outer ear infection by inhibiting the growth of bacteria and fungus. This, in turn, reduces the pain and swelling associated with the infection. Wetness in the ear canal provides an environment conducive to the growth of bacteria and fungus, so treating the infection is necessary to alleviate these symptoms."

Answered by AI

Is hydrocortisone good for ear infection?

"Hydrocortisone is a steroid medicine that can be used to relieve symptoms such as redness, itching, and swelling caused by ear infections. A prescription from a doctor is required to obtain this medicine."

Answered by AI

What is hydrocortisone and acetic acid solution used for?

"Hydrocortisone is a medication that reduces inflammation. Acetic acid and hydrocortisone otic is a combination medication used to treat infections in the ear canal and relieve the symptoms of redness, itching, or swelling."

Answered by AI

Does acetic acid dissolve ear wax?

"There are eardrops that you can buy without a prescription that will dissolve earwax. These water-based eardrops contain either acetic acid, hydrogen peroxide, or sodium bicarbonate. Oil-based earwax dissolvers lubricate and soften the earwax."

Answered by AI

Clinical Trials for Hydrocortisone And Acetic Acid

Image of National Institutes of Health Clinical Center in Bethesda, United States.

gp91 Grans for Chronic Granulomatous Disease

18 - 75
Male
Bethesda, MD

Background: CGD is caused by a gene mutation. For people with CGD, their cells cannot kill germs well, so they can get frequent or life-threatening infections. Researchers want to see if a new procedure can help a person s cells kill germs for a short time. It uses messenger RNA (mRNA) to deliver correct instructions for the gene mutation to the cells. Objective: To test a procedure in which mRNA is added to a person s blood cells. Eligibility: Males aged 18-75 with CGD with a mutation in the gene that makes the protein gp91phox. Design: Participants will be screened with: Medical history Physical exam Blood and urine tests Swab to test for strep throat Some screening tests will be repeated during the study. Participants will be admitted to the NIH Clinical Center hospital for at least 7 days. They will have apheresis. For this, a medicine is injected under their skin to prepare their white blood cells for collection. An IV line is placed into an arm vein. Blood goes through the IV line into a machine that divides whole blood into red blood cells, plasma, and white blood cells. The white blood cells are removed, and the rest of the blood is returned to the participant through an IV line in their other arm. The next day, they will get their mRNA-corrected cells via IV. They will be monitored for 3 more days. After discharge, participants will keep a symptom diary. They will be contacted weekly for one month, and then once a month. They will have a follow-up visit 3 months after the infusion.

Phase 1
Recruiting

National Institutes of Health Clinical Center

Suk S De Ravin, M.D.

Image of University of Iowa in Iowa City, United States.

Improved Perioperative Preventive Measures for Surgical Site Infections

18+
All Sexes
Iowa City, IA

Surgical site infections (SSIs) are associated with increased patient morbidity, mortality, and healthcare costs. ESKAPE (Enterococcus, S. aureus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) pathogens are particularly pathogenic because they have increased capacity to acquire resistance and virulence traits. The investigators have proven that a multifaceted program involving improved basic perioperative preventive measures can generate substantial reductions in S. aureus transmission and significant reductions in SSIs (88% reduction as compared to usual care). In this study, the investigators aim to examine the relative effectiveness of each component of this program in controlling ESKAPE transmission and reducing SSIs and to identify an optimal implementation strategy for national dissemination. Randomization occurs at the site level, and sites adopt preventative programs. This work will improve perioperative patient safety for the 51 million patients who undergo surgery each year.

Recruiting
Has No Placebo

University of Iowa (+2 Sites)

Jeremiah R Brown, PhD

Image of University of Ottawa Heart Institute in Ottawa, Canada.

Barrier Dressing for Infections

18+
All Sexes
Ottawa, Canada

This study will evaluate the effect of an iodine impregnated barrier dressing on device pocket swab culture positivity. Minimizing contamination during the implant procedure can be one of the potential improvements to prevent CIED infections. Patients requiring a lead change, battery change or device upgrade will be eligible. This is a randomized, blinded study where participants will be randomized to having the barrier dressing applied before any incision is made (experimental group) or applying the dressing just prior to collecting the culture swab (control group). Patients and the staff taking the culture swab at the end of the procedure are blinded as to which group the participant is randomized to.

Waitlist Available
Has No Placebo

University of Ottawa Heart Institute

Alper Aydin, Dr.

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