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What is Halobetasol Propionate
UlobetasolThe Generic name of this drug
Treatment SummaryUlobetasol is a very strong steroid drug prescribed to treat severe cases of psoriasis and other skin conditions that respond to steroids. It was approved by the FDA in 1990.
Halobetasol Propionateis the brand name
Halobetasol Propionate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Halobetasol Propionate
Ulobetasol
2004
38
Effectiveness
How Halobetasol Propionate Affects PatientsUlobetasol is a type of corticosteroid that helps to reduce inflammation. It is usually applied once or twice a day and has a wide therapeutic window, meaning that it is safe to take doses higher than what the body naturally produces. It is important to be aware that taking corticosteroids can suppress the body's natural hormone system and make it harder to fight infections.
How Halobetasol Propionate works in the bodyCorticosteroids help reduce inflammation in the body. They work by preventing certain cells from migrating to the site of inflammation, and by blocking the production of certain molecules that cause inflammation. Low doses of corticosteroids reduce inflammation, while high doses suppress the immune system. High doses of corticosteroids can also lead to higher sodium levels and lower potassium levels.
When to interrupt dosage
The proposed dosage of Halobetasol Propionate is dependent upon the diagnosed situation, such as Pruritus, corticosteroid responsive, Inflammatory Dermatosis and Plaque Psoriasis. The quantity of dosage is contingent upon the delivery approach (e.g. Lotion - Topical or Cream) specified in the table below.Condition
Dosage
Administration
corticosteroid responsive, Inflammatory Dermatosis
, 0.0005 mg/mg, 0.05 %, 0.0001 mg/mg, 0.01 %
, Topical, Cream - Topical, Cream, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Kit, Aerosol, foam - Topical, Aerosol, foam, Kit - Topical
Pruritus
, 0.0005 mg/mg, 0.05 %, 0.0001 mg/mg, 0.01 %
, Topical, Cream - Topical, Cream, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Kit, Aerosol, foam - Topical, Aerosol, foam, Kit - Topical
Psoriasis Vulgaris
, 0.0005 mg/mg, 0.05 %, 0.0001 mg/mg, 0.01 %
, Topical, Cream - Topical, Cream, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Kit, Aerosol, foam - Topical, Aerosol, foam, Kit - Topical
Warnings
Halobetasol Propionate has one contraindication. It should not be combined with the conditions enumerated in the following table.Halobetasol Propionate ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Ulobetasol may interact with Pulse Frequency
Common Halobetasol Propionate Drug Interactions
Drug Name
Risk Level
Description
Allogeneic processed thymus tissue
Minor
The therapeutic efficacy of Allogeneic processed thymus tissue can be decreased when used in combination with Ulobetasol.
Inebilizumab
Minor
The risk or severity of infection can be increased when Ulobetasol is combined with Inebilizumab.
Vibrio cholerae CVD 103-HgR strain live antigen
Minor
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Ulobetasol.
2,4-thiazolidinedione
Moderate
The risk or severity of hyperglycemia can be increased when Ulobetasol is combined with 2,4-thiazolidinedione.
AICA ribonucleotide
Moderate
The risk or severity of hyperglycemia can be increased when Ulobetasol is combined with AICA ribonucleotide.
Halobetasol Propionate Toxicity & Overdose RiskPeople who take glucocorticoids in high doses for a long period of time are at risk of developing cataracts, glaucoma, high blood pressure, water retention, high cholesterol, ulcers, pancreatitis, muscle weakness, changes in mood or behavior, skin thinning, allergies, acne, increased hair growth, weakened immune system, diabetes, low calcium and phosphorous levels, acidosis, slower growth, and low secondary adrenal hormones. If someone has taken too much glucocorticoids, the dose may be reduced or stopped and supportive treatments should be given.
Halobetasol Propionate Novel Uses: Which Conditions Have a Clinical Trial Featuring Halobetasol Propionate?
18 active clinical trials are currently assessing the potential of Halobetasol Propionate to alleviate Pruritus, Plaque Psoriasis and corticosteroid responsive Inflammatory Dermatoses.Condition
Clinical Trials
Trial Phases
Pruritus
0 Actively Recruiting
corticosteroid responsive, Inflammatory Dermatosis
0 Actively Recruiting
Psoriasis Vulgaris
20 Actively Recruiting
Early Phase 1, Phase 4, Phase 3, Not Applicable, Phase 2
Halobetasol Propionate Reviews: What are patients saying about Halobetasol Propionate?
5Patient Review
5/23/2013 This medication has done wonders for my acne keloidalis nuchae. Most of the acne is gone and it's prevented any new breakouts. The only downside is that it's a bit pricey; a small tube costs about $25 at my local CVS.
5Patient Review
12/16/2011 I've been using this treatment for almost 20 years on and off, and I have to say that it's the only thing that really works well for me.
5Patient Review
5/12/2014 This medication is excellent for Atopic Dermatitis. The rash disappears within 4 to 5 days, and if it comes back, the same process yields great results once again.
5Patient Review
8/5/2014 This is the first and only medication that has been able to immediately stop the extreme itching I experience from eczema. It also helps heal skin eruptions and cracking skin. Unfortunately, the problem always returns but this cream really does help lessen the symptoms.
5Patient Review
7/5/2022 Halobetasol rapidly and effectively resolved the radiation-induced dermatitis on my hand.
5Patient Review
8/12/2017 Worked great the first time I used it, but not so much the second. Not sure what changed, but this treatment didn't work as well the second time around.
5Patient Review
6/23/20105Patient Review
9/23/2017 This cleared up my hand rash after just two applications. Other medications I've tried were completely ineffective.
5Patient Review
11/19/2014 Not very effective.
5Patient Review
6/5/2015 I'm wondering if anyone else who has used Halobetasol has developed any pituitary issues, like tumors? I've been reading the insert in my second RX for this medicine and now I'm concerned it might be connected to some recent medical issues I've had.
4.7Patient Review
6/26/2013 I tried this medication for an entire year, and unfortunately, it did not help me. My nails are also falling apart now. I'm going to seek out a new doctor's opinion soon.
4.3Patient Review
9/7/2016 I've been using this ointment on and off for the past fifteen years to manage my atopic dermatitis, which only affects my hands and is humidity-activated. It's always worked well for me and I vastly prefer it to oral prednisone!
3.7Patient Review
7/5/2014 Unacceptable side effects included anal irritation and pain, bowel and stomach irritation and sharp tingling, testicular soreness, and dizziness.
3.3Patient Review
6/16/2017 This cream helps me a lot when my hands start shaking.
3Patient Review
3/29/2011 This treatment can be effective, but it's not very practical for large areas of skin or scalp.
3Patient Review
7/14/20093Patient Review
5/23/20102.7Patient Review
2/14/2014 I had a bad reaction to a plant that resulted in my face being swollen, burning, cracking, and oozing. This product provided some relief within the first application and I was healed completely within a week.
1.3Patient Review
8/16/2012 I tried this medication after using Olux, in hopes that it would be more effective at preventing dryness. It worked for a little while, but my body got used to it and it became ineffective.
Patient Q&A Section about halobetasol propionate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is halobetasol propionate a strong steroid?
"Halobetasol is a very powerful steroid that is applied to the skin to ease redness and itching that is brought about by certain skin conditions."
Answered by AI
How long does it take for halobetasol to work?
"If your skin condition does not improve after two weeks of treatment, give your doctor a call."
Answered by AI
Is halobetasol propionate cream used for eczema?
"This medication is used to treat various skin conditions by reducing swelling, itching, and redness. It is a very strong corticosteroid."
Answered by AI
What is halobetasol propionate ointment used for?
"Halobetasol is a topical medicine used to relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis. This medicine is a corticosteroid (cortisone-like medicine or steroid). This medicine is available only with your doctor's prescription."
Answered by AI