Halobetasol Propionate

corticosteroid responsive, Inflammatory Dermatosis, Pruritus, Psoriasis Vulgaris
Treatment
20 Active Studies for Halobetasol Propionate

What is Halobetasol Propionate

UlobetasolThe Generic name of this drug
Treatment SummaryUlobetasol is a very strong steroid drug prescribed to treat severe cases of psoriasis and other skin conditions that respond to steroids. It was approved by the FDA in 1990.
Halobetasol Propionateis the brand name
image of different drug pills on a surface
Halobetasol Propionate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Halobetasol Propionate
Ulobetasol
2004
38

Effectiveness

How Halobetasol Propionate Affects PatientsUlobetasol is a type of corticosteroid that helps to reduce inflammation. It is usually applied once or twice a day and has a wide therapeutic window, meaning that it is safe to take doses higher than what the body naturally produces. It is important to be aware that taking corticosteroids can suppress the body's natural hormone system and make it harder to fight infections.
How Halobetasol Propionate works in the bodyCorticosteroids help reduce inflammation in the body. They work by preventing certain cells from migrating to the site of inflammation, and by blocking the production of certain molecules that cause inflammation. Low doses of corticosteroids reduce inflammation, while high doses suppress the immune system. High doses of corticosteroids can also lead to higher sodium levels and lower potassium levels.

When to interrupt dosage

The proposed dosage of Halobetasol Propionate is dependent upon the diagnosed situation, such as Pruritus, corticosteroid responsive, Inflammatory Dermatosis and Plaque Psoriasis. The quantity of dosage is contingent upon the delivery approach (e.g. Lotion - Topical or Cream) specified in the table below.
Condition
Dosage
Administration
corticosteroid responsive, Inflammatory Dermatosis
, 0.0005 mg/mg, 0.05 %, 0.0001 mg/mg, 0.01 %
, Topical, Cream - Topical, Cream, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Kit, Aerosol, foam - Topical, Aerosol, foam, Kit - Topical
Pruritus
, 0.0005 mg/mg, 0.05 %, 0.0001 mg/mg, 0.01 %
, Topical, Cream - Topical, Cream, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Kit, Aerosol, foam - Topical, Aerosol, foam, Kit - Topical
Psoriasis Vulgaris
, 0.0005 mg/mg, 0.05 %, 0.0001 mg/mg, 0.01 %
, Topical, Cream - Topical, Cream, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Kit, Aerosol, foam - Topical, Aerosol, foam, Kit - Topical

Warnings

Halobetasol Propionate has one contraindication. It should not be combined with the conditions enumerated in the following table.Halobetasol Propionate Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Ulobetasol may interact with Pulse Frequency
There are 20 known major drug interactions with Halobetasol Propionate.
Common Halobetasol Propionate Drug Interactions
Drug Name
Risk Level
Description
Allogeneic processed thymus tissue
Minor
The therapeutic efficacy of Allogeneic processed thymus tissue can be decreased when used in combination with Ulobetasol.
Inebilizumab
Minor
The risk or severity of infection can be increased when Ulobetasol is combined with Inebilizumab.
Vibrio cholerae CVD 103-HgR strain live antigen
Minor
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Ulobetasol.
2,4-thiazolidinedione
Moderate
The risk or severity of hyperglycemia can be increased when Ulobetasol is combined with 2,4-thiazolidinedione.
AICA ribonucleotide
Moderate
The risk or severity of hyperglycemia can be increased when Ulobetasol is combined with AICA ribonucleotide.
Halobetasol Propionate Toxicity & Overdose RiskPeople who take glucocorticoids in high doses for a long period of time are at risk of developing cataracts, glaucoma, high blood pressure, water retention, high cholesterol, ulcers, pancreatitis, muscle weakness, changes in mood or behavior, skin thinning, allergies, acne, increased hair growth, weakened immune system, diabetes, low calcium and phosphorous levels, acidosis, slower growth, and low secondary adrenal hormones. If someone has taken too much glucocorticoids, the dose may be reduced or stopped and supportive treatments should be given.
image of a doctor in a lab doing drug, clinical research

Halobetasol Propionate Novel Uses: Which Conditions Have a Clinical Trial Featuring Halobetasol Propionate?

18 active clinical trials are currently assessing the potential of Halobetasol Propionate to alleviate Pruritus, Plaque Psoriasis and corticosteroid responsive Inflammatory Dermatoses.
Condition
Clinical Trials
Trial Phases
Psoriasis Vulgaris
23 Actively Recruiting
Early Phase 1, Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1
corticosteroid responsive, Inflammatory Dermatosis
0 Actively Recruiting
Pruritus
0 Actively Recruiting

Halobetasol Propionate Reviews: What are patients saying about Halobetasol Propionate?

5Patient Review
5/23/2013
Halobetasol Propionate for Inflammation of Skin caused by an Allergy
This medication has done wonders for my acne keloidalis nuchae. Most of the acne is gone and it's prevented any new breakouts. The only downside is that it's a bit pricey; a small tube costs about $25 at my local CVS.
5Patient Review
12/16/2011
Halobetasol Propionate for Plaque Psoriasis
I've been using this treatment for almost 20 years on and off, and I have to say that it's the only thing that really works well for me.
5Patient Review
5/12/2014
Halobetasol Propionate for Atopic Dermatitis
This medication is excellent for Atopic Dermatitis. The rash disappears within 4 to 5 days, and if it comes back, the same process yields great results once again.
5Patient Review
8/5/2014
Halobetasol Propionate for Plaque Psoriasis
This is the first and only medication that has been able to immediately stop the extreme itching I experience from eczema. It also helps heal skin eruptions and cracking skin. Unfortunately, the problem always returns but this cream really does help lessen the symptoms.
5Patient Review
7/5/2022
Halobetasol Propionate for Skin Inflammation
Halobetasol rapidly and effectively resolved the radiation-induced dermatitis on my hand.
5Patient Review
8/12/2017
Halobetasol Propionate for Plaque Psoriasis
Worked great the first time I used it, but not so much the second. Not sure what changed, but this treatment didn't work as well the second time around.
5Patient Review
6/23/2010
Halobetasol Propionate for Plaque Psoriasis
5Patient Review
9/23/2017
Halobetasol Propionate for Skin Condition
This cleared up my hand rash after just two applications. Other medications I've tried were completely ineffective.
5Patient Review
11/19/2014
Halobetasol Propionate for Rash
Not very effective.
5Patient Review
6/5/2015
Halobetasol Propionate for Atopic Dermatitis
I'm wondering if anyone else who has used Halobetasol has developed any pituitary issues, like tumors? I've been reading the insert in my second RX for this medicine and now I'm concerned it might be connected to some recent medical issues I've had.
4.7Patient Review
6/26/2013
Halobetasol Propionate for Atopic Dermatitis
I tried this medication for an entire year, and unfortunately, it did not help me. My nails are also falling apart now. I'm going to seek out a new doctor's opinion soon.
4.3Patient Review
9/7/2016
Halobetasol Propionate for Plaque Psoriasis
I've been using this ointment on and off for the past fifteen years to manage my atopic dermatitis, which only affects my hands and is humidity-activated. It's always worked well for me and I vastly prefer it to oral prednisone!
3.7Patient Review
7/5/2014
Halobetasol Propionate for Skin Rash that Becomes Thick & Discolored From Rubbing It
Unacceptable side effects included anal irritation and pain, bowel and stomach irritation and sharp tingling, testicular soreness, and dizziness.
3.3Patient Review
6/16/2017
Halobetasol Propionate for Plaque Psoriasis
This cream helps me a lot when my hands start shaking.
3Patient Review
3/29/2011
Halobetasol Propionate for Plaque Psoriasis
This treatment can be effective, but it's not very practical for large areas of skin or scalp.
3Patient Review
7/14/2009
Halobetasol Propionate for Plaque Psoriasis
3Patient Review
5/23/2010
Halobetasol Propionate for Genital Itching
2.7Patient Review
2/14/2014
Halobetasol Propionate for Anal Itching
I had a bad reaction to a plant that resulted in my face being swollen, burning, cracking, and oozing. This product provided some relief within the first application and I was healed completely within a week.
1.3Patient Review
8/16/2012
Halobetasol Propionate for Reddish Nodules Arranged in a Circle On the Skin
I tried this medication after using Olux, in hopes that it would be more effective at preventing dryness. It worked for a little while, but my body got used to it and it became ineffective.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about halobetasol propionate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is halobetasol propionate a strong steroid?

"Halobetasol is a very powerful steroid that is applied to the skin to ease redness and itching that is brought about by certain skin conditions."

Answered by AI

How long does it take for halobetasol to work?

"If your skin condition does not improve after two weeks of treatment, give your doctor a call."

Answered by AI

Is halobetasol propionate cream used for eczema?

"This medication is used to treat various skin conditions by reducing swelling, itching, and redness. It is a very strong corticosteroid."

Answered by AI

What is halobetasol propionate ointment used for?

"Halobetasol is a topical medicine used to relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis. This medicine is a corticosteroid (cortisone-like medicine or steroid). This medicine is available only with your doctor's prescription."

Answered by AI

Clinical Trials for Halobetasol Propionate

Have you considered Halobetasol Propionate clinical trials? We made a collection of clinical trials featuring Halobetasol Propionate, we think they might fit your search criteria.Go to Trials
Image of Lynderm Research in Markham, Canada.

ESK-001 for Plaque Psoriasis

18+
All Sexes
Markham, Canada
The objective of the ESK-001-018 long term extension is to evaluate the safety and efficacy of ESK-001 over time. The scientific questions it aims to answer are: * How safe is taking ESK-001 long-term in people with moderate to severe plaque psoriasis? * Does taking ESK-001 long-term reduce the severity of people's plaque psoriasis? Patients will enter the long-term extension study following completion of one of the parent studies (ESK-001-016 or ESK-001-017) and will receive open-label ESK-001 twice daily for 24 weeks. After 24 weeks, the first 200 patients meeting at least PASI-75 clinical response will be randomly assigned to receive ESK-001 or placebo. At any point during this time, the patients losing the initial clinical response may return to the open-label ESK-001 treatment. Patients who complete Week 48 will return to open-label ESK-001 treatment and they will receive ESK-001 until the end of the study or discontinuation. All the remaining patients not meeting the entry criteria for the randomized withdrawal phase will continue to receive open-label ESK-001 for the remainder of the study. Patients taking part in the study must be men or women aged at least 18 years old and have completed a previous (parent) study of ESK-001 in moderate to severe plaque psoriasis. Patients must consent and agree to: * ensure drug daily compliance until end of study or discontinuation. * visit the clinic for checkups and assessments. * provide blood and urine samples.
Phase 3
Recruiting
Quick Reply
Lynderm Research (+35 Sites)Alumis Inc
Image of Not posted in Webster, United States.

IRX4204 for Plaque Psoriasis

18+
All Sexes
Webster, TX
The goal of this clinical trial is to learn if IRX4204 works to treat plaque psoriasis in adults. It will also learn about the safety of IRX4204. The main questions it aims to answer are: * Does IRX4204 treat plaque psoriasis symptoms? * Does IRX4204 treat plaque psoriasis symptoms better than someone who is not being treated? * What medical problems do participants have when taking IRX4204? Researchers will compare IRX4204 to a placebo (a look-alike substance that contains no drug) to see if the drug works to treat mild to moderate plaque psoriasis. Participants will: * Take IRX4204 every day for 28 days * Visit the clinic once every week for checkups and tests * Complete specific assessments about plaque psoriasis and changes to plaques
Phase 2
Waitlist Available
Not postedIo Therapeutics
Have you considered Halobetasol Propionate clinical trials? We made a collection of clinical trials featuring Halobetasol Propionate, we think they might fit your search criteria.Go to Trials
Have you considered Halobetasol Propionate clinical trials? We made a collection of clinical trials featuring Halobetasol Propionate, we think they might fit your search criteria.Go to Trials
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