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What is Geodon
ZiprasidoneThe Generic name of this drug
Treatment SummaryZiprasidone is a medication used to treat mental illnesses such as schizophrenia and bipolar disorder. It is classified as an atypical antipsychotic, which means it is thought to be as effective as traditional antipsychotics but has fewer side effects, such as weight gain and impaired glucose tolerance. Ziprasidone is often prescribed to reduce the rate and time of relapses in schizophrenia and can be used to treat manic episodes in bipolar disorder, although the exact mechanism of action is unknown. Compared to other atypical antipsychotics, ziprasidone has a lower risk of metabolic side effects.
Geodonis the brand name
Geodon Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Geodon
Ziprasidone
2001
250
Approved as Treatment by the FDA
Ziprasidone, also called Geodon, is approved by the FDA for 2 uses which include Bipolar Disorder and Acute Coryza .Bipolar Disorder
Acute Coryza
Effectiveness
How Geodon Affects PatientsZiprasidone is an "atypical" antipsychotic drug that works by blocking dopamine and serotonin receptors. It has a very high affinity for serotonin receptors and prevents the reuptake of serotonin and norepinephrine. It also has a low affinity for certain types of nerve cells that help regulate functions like muscle movement, the immune system, and sleep.
How Geodon works in the bodyZiprasidone is an antipsychotic medication that works differently than other similar medications. It has a higher affinity for certain receptors in the brain, allowing for improved mood, relief from negative symptoms, better cognitive function, and less motor dysfunction. It is also linked to antidepressant and anxiolytic activity. Ziprasidone's lower affinity for certain other receptors help reduce side effects like orthostatic hypotension, cognitive disturbance, sedation, weight gain, and prolactin disruption.
When to interrupt dosage
The prescribed measure of Geodon is contingent upon the designated affliction, including Alzheimer's Disease, Bipolar Disorder and Acute Coryza. The amount of dosage is contingent upon the process of administration indicated in the table beneath.Condition
Dosage
Administration
Schizophrenia
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Acute Agitation
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
acute Mixed manic depressive episode
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Bipolar Disorder
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Agitation
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Alzheimer's Disease
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Acute Coryza
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Schizophrenia
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Unipolar Depression
20.0 mg, 40.0 mg, 60.0 mg, , 80.0 mg, 20.0 mg/mL
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular
Warnings
Geodon ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Myocardial Infarction
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Heart Decompensation
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
history of QT prolongation
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ziprasidone may interact with Pulse Frequency
Common Geodon Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Ziprasidone.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Ziprasidone.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Ziprasidone is combined with Aclidinium.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Ziprasidone.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Ziprasidone.
Geodon Toxicity & Overdose RiskTaking ziprasidone may lead to side effects such as drowsiness, breathing problems, muscle tremors, dizziness, restlessness, abnormal vision, weakness, vomiting, headache, and nausea.
Geodon Novel Uses: Which Conditions Have a Clinical Trial Featuring Geodon?
At present, 456 active trials are being conducted to examine the potential of Geodon in alleviating Agitation, Alzheimer's Disease and Schizophrenia.Condition
Clinical Trials
Trial Phases
Bipolar Disorder
1 Actively Recruiting
Phase 4
Schizophrenia
175 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Alzheimer's Disease
253 Actively Recruiting
Phase 1, Phase 4, Phase 2, Phase 3, Not Applicable, Early Phase 1
Unipolar Depression
1 Actively Recruiting
Not Applicable
Acute Coryza
1 Actively Recruiting
Not Applicable
Acute Agitation
0 Actively Recruiting
acute Mixed manic depressive episode
0 Actively Recruiting
Agitation
5 Actively Recruiting
Phase 3, Phase 2
Schizophrenia
34 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Geodon Reviews: What are patients saying about Geodon?
5Patient Review
9/5/2018 I was patient with this treatment, and it paid off. After about a month, I saw great results.
5Patient Review
11/15/2019 This drug, in combination with Lamictal, has been wonderful for me. I was able to lose over 100 pounds while taking this medication. I highly recommend it.
5Patient Review
12/17/2021 This drug has been a huge help for me. I was struggling with depression and fatigue, but since my doctor increased my dosage, I've had so much more energy and motivation.
5Patient Review
1/6/2019 I'm really glad I decided to give this medication a try. It's been a total game-changer for me, better than any other antipsychotic I've tried. It's helped stabilize my mood and significantly decreased the hallucinations I experience. The only downside is that it sometimes makes me drowsy, but even that has gotten better over time.
4.7Patient Review
8/26/2022 Geodon has been a godsend for me. I've been taking it for seven months now and my bipolar 2 is so much more manageable. I'm able to handle stressors better and don't sink into deep depressions as easily or as severely. And, thankfully, I didn't experience any weight gain!
4.7Patient Review
4/24/2019 This drug is effective and helps me stay alert.
1.7Patient Review
9/12/2022 I ballooned from 60 to 130 pounds in just six months while on this medication. As soon as I stopped taking it, the weight melted off.
1Patient Review
5/13/2018 Be careful with this medication. I was given it by the VA for being bipolar, and started seeing tardive dystonia as a result. It's incurable, and I'm now trying to wean myself off of the drug entirely.
1Patient Review
10/31/2018 I took this medication and had a very negative reaction to it. I became extremely depressed and suicidal.
1Patient Review
4/5/2019 This drug was really tough for me to take. I had a lot of trouble remembering things.
Patient Q&A Section about geodon
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Geodon good for anxiety?
"The study found that adding ziprasidone to escitalopram was equally effective in treating depression with or without anxiety. However, the study also found that the observed anxiolytic effect size was not clinically significant for patients with higher levels of anxiety."
Answered by AI
Is Geodon a mood stabilizer or antipsychotic?
"Geodon is an antipsychotic drug that is used to treat symptoms of schizophrenia and bipolar disorder. It is indicated for use in the United States to help manage symptoms of these conditions."
Answered by AI
What are the most common side effects of Geodon?
"You may feel drowsy, dizzy, lightheaded, weak, nauseous, or vomit after taking this medication. If you have a runny nose or cough, tell your doctor. These symptoms may last or get worse. Be careful if you feel dizzy or lightheaded, as you could fall."
Answered by AI
What is the drug Geodon used for?
"Ziprasidone is a medication that works in the brain to treat schizophrenia. It is a second generation antipsychotic medication that works to improve thinking, mood, and behavior by rebalancing dopamine and serotonin."
Answered by AI