Study Summary
This trial will test how well a new cancer drug called zilovertamab vedotin works and how safe it is.
- Diffuse Large B Cell Lymphoma (DLBCL)
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: Up to approximately 50 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
3 Treatment Groups
Arm A
1 of 3
Arm B
1 of 3
MK-2140 (zilovertamab vedotin)
1 of 3
Experimental Treatment
140 Total Participants · 3 Treatment Groups
Primary Treatment: MK-2140 (zilovertamab vedotin) · No Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Has MK-2140 (zilovertamab vedotin) been formally sanctioned by the FDA?
"There is a limited amount of evidence suggesting the safety of MK-2140 (zilovertamab vedotin), thus it received an assessment score of 2. No data exists that confirms its efficacy." - Anonymous Online Contributor
How many institutes are participating in the experiment?
"The clinical trial is being conducted in multiple sites throughout the US, including AHN West Penn Hospital (Site 0212) in Pittsburgh, Pennsylvania; Saint Louis University Cancer Center ( Site 0209) in St. Louis, Missouri; and St. Joseph Hospital-The Center for Cancer Prevention and Treatment ( Site 0229) located in Orange , California amongst 16 other locations." - Anonymous Online Contributor
How many volunteers are participating in this research initiative?
"The sponsor of this trial, Merck Sharp & Dohme Corp., is in search of a total 100 patients who meet the criteria to partake. Patients can be seen at AHN West Penn Hospital ( Site 0212) in Pittsburgh, Pennsylvania and Saint Louis University Cancer Center (Site 0209) in Saint Louis, Missouri amongst other locations." - Anonymous Online Contributor
Is recruitment still ongoing for this investigation?
"Affirmative. The information hosted on clinicaltrials.gov states that this medical research is currently recruiting volunteers, and was first posted in the 8th of January 2022 with an update made at 24th November 2022. To be precise, 100 individuals are desired to join from 16 different trial sites." - Anonymous Online Contributor