Treatment for Stroke

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Feinstein Institutes at Northwell Health, Manhasset, NY
Stroke+2 More
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

To determine whether treatment with transauricular vagus nerve stimulation (taVNS) during the training of an affected upper limb of a patient with chronic stroke on a robotic motor task alters the motor impairment.

Eligible Conditions

  • Stroke
  • Hemiparesis

Treatment Effectiveness

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 30-45minutes

30-45minutes
Action Research Arm Test (ARAT)
Fugl-Meyer Motor Scale for the upper extremity

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

Unaffected limb
1 of 2
Affected Limb
1 of 2
Active Control
Non-Treatment Group

45 Total Participants · 2 Treatment Groups

Primary Treatment: Treatment · Has Placebo Group · Phase 2

Unaffected limbNoIntervention Group · 1 Intervention: Unaffected limb · Intervention Types:
Affected Limb
Device
ShamComparator Group · 1 Intervention: In Motion Rehabilitation Robot · Intervention Types: Device

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 30-45minutes
Closest Location: Feinstein Institutes at Northwell Health · Manhasset, NY
Photo of new york 1Photo of new york 2Photo of new york 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Stroke
0 CompletedClinical Trials

Who is running the clinical trial?

Northwell HealthLead Sponsor
409 Previous Clinical Trials
290,165 Total Patients Enrolled
11 Trials studying Stroke
343 Patients Enrolled for Stroke
Bruce T Volpe, MDPrincipal InvestigatorFeinstein Center for Molecular Medicine
4 Previous Clinical Trials
106 Total Patients Enrolled
4 Trials studying Stroke
106 Patients Enrolled for Stroke
Timir Datta Chaudhuri, PhDStudy DirectorFeinstein Center for Bioelectronic Medicine

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have no recent upper respiratory symptoms and no loss of taste or olfaction.
You have hemiplegia or fully recovered motor function in the muscles of the shoulder, elbow, and wrist.
You are between 18 and 85 years of age.
You have a first single focal unilateral supratentorial ischemic stroke that occurred at least 6 months prior to the study

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.