VTX958 for Crohn's Disease
(Harmony-CD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing a new medication called VTX958 to help people with moderate to severe Crohn's Disease. The goal is to see if it can reduce inflammation in the intestines and improve symptoms. The study will involve several phases over a period of up to three years.
Are You a Good Fit for This Trial?
This trial is for men and women aged 18-75 with a confirmed diagnosis of Crohn's Disease (CD) that's moderately to severely active. They must have known they had CD for at least 3 months and be able to consent. People can't join if they've tried VTX958 or similar drugs, have other types of colitis, complications from CD requiring surgery, or have a stoma or ileoanal pouch.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Induction Treatment
Participants receive double-blind treatment to evaluate the efficacy and safety of VTX958
Maintenance Treatment
Participants continue double-blind treatment to maintain response
Open-Label Extension
Participants may opt into continuation of treatment long-term
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- VTX958
- VTX958 Placebo
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ventyx Biosciences, Inc
Lead Sponsor