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IV Diuretics for Heart Failure

N/A

Recruiting

Led By Stephen Greene

Research Sponsored by Duke University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

≥18 years of age

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 90 days

Awards & highlights

Study Summary

This trial is testing if IV diuretics can help improve heart failure symptoms when taken at home. #OUTPATIENT-WHF

Who is the study for?

This trial is for adults over 18 with worsening heart failure who need IV diuretics, as judged by their doctor. They must have completed a health survey and be able to consent. It's not for those with heart devices, severe kidney disease on dialysis, new heart failure diagnosis, pregnancy, high fever at screening or any condition affecting study compliance.Check my eligibility

What is being tested?

The OUTPATIENT-WHF study tests if giving IV diuretics in an outpatient clinic can effectively treat worsening heart failure compared to the usual initial hospitalization strategy. Patients will either receive treatment in the clinic or be hospitalized.See study design

What are the potential side effects?

While specific side effects are not listed here, generally IV diuretics can cause electrolyte imbalances, kidney issues or low blood pressure. The exact side effects will depend on individual patient conditions and responses.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 90 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~90 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 90 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Secondary outcome measures

Days alive and out of hospital

Death

Health status as measured by EuroQOL-5 dimensions (EQ5D) utility index

+3 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Initial outpatient management strategy, including outpatient IV diuretics in clinicExperimental Treatment1 Intervention

Group II: Initial hospitalization-based management strategyExperimental Treatment1 Intervention

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor

2,364 Previous Clinical Trials

3,420,572 Total Patients Enrolled

63 Trials studying Heart Failure

46,447 Patients Enrolled for Heart Failure

Stephen GreenePrincipal InvestigatorDuke University

Media Library

Initial Hospitalization-based Management Strategy Clinical Trial Eligibility Overview. Trial Name: NCT05704595 — N/A

Heart Failure Research Study Groups: Initial outpatient management strategy, including outpatient IV diuretics in clinic, Initial hospitalization-based management strategy

Heart Failure Clinical Trial 2023: Initial Hospitalization-based Management Strategy Highlights & Side Effects. Trial Name: NCT05704595 — N/A

Initial Hospitalization-based Management Strategy 2023 Treatment Timeline for Medical Study. Trial Name: NCT05704595 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many subjects are participating in this experiment?

"Affirmative. According to clinicaltrials.gov, this ongoing medical experiment is presently enrolling volunteers for participation; it was first uploaded on March 27th 2023 and most recently modified on April 10th 2023. Seventy participants are needed at a single location."

Answered by AI

Are there any vacancies still available for participants in this research?

"Clinicaltrials.gov reveals that this is an ongoing clinical trial, which initially posted on March 27th 2023 and was most recently amended on April 10th 2023."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

2023. "Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05704595.