Gemifloxacin Mesylate

Multidrug resistant Streptococcus pneumoniae infection, bacterial rhinosinusitis, Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) + 3 more
Treatment
4 FDA approvals
20 Active Studies for Gemifloxacin Mesylate

What is Gemifloxacin Mesylate

GemifloxacinThe Generic name of this drug
Treatment SummaryGemifloxacin is an antibiotic used to treat acute cases of chronic bronchitis and mild-to-moderate pneumonia. It comes in tablet form and works by blocking the growth of bacteria by targeting their DNA. Gemifloxacin targets both DNA gyrase and topoisomerase IV, two key components in the growth of bacteria.
Factiveis the brand name
Gemifloxacin Mesylate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Factive
Gemifloxacin
2003
4

Approved as Treatment by the FDA

Gemifloxacin, otherwise known as Factive, is approved by the FDA for 4 uses like Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) and Urinary Tract Infection (UTI) .
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
Urinary Tract Infection (UTI)
Multidrug resistant Streptococcus pneumoniae infection
Community Acquired Pneumonia (CAP)

Effectiveness

How Gemifloxacin Mesylate Affects PatientsGemifloxacin is an antibiotic used to fight bacteria in the body. This drug works by attaching to an enzyme called DNA gyrase, which is important for bacteria to replicate. It attaches much more strongly to the bacterial version of this enzyme than the human version, which helps it fight bacteria without affecting us. Gemifloxacin can fight both Gram-positive and Gram-negative bacteria.
How Gemifloxacin Mesylate works in the bodyGemifloxacin kills bacteria by preventing them from replicating their DNA. It does this by blocking two enzymes that are needed for the process.

When to interrupt dosage

The measure of Gemifloxacin Mesylate is contingent upon the determined ailment, including Urinary Tract Infection (UTI), Community Acquired Pneumonia (CAP) and bacterial rhinosinusitis. The amount of dosage fluctuates in accordance with the technique of delivery featured in the table beneath.
Condition
Dosage
Administration
Community Acquired Pneumonia (CAP)
, 320.0 mg
, Tablet - Oral, Tablet, Tablet, film coated - Oral, Oral, Tablet, film coated
bacterial rhinosinusitis
, 320.0 mg
, Tablet - Oral, Tablet, Tablet, film coated - Oral, Oral, Tablet, film coated
Urinary Tract Infection (UTI)
, 320.0 mg
, Tablet - Oral, Tablet, Tablet, film coated - Oral, Oral, Tablet, film coated
Multidrug resistant Streptococcus pneumoniae infection
, 320.0 mg
, Tablet - Oral, Tablet, Tablet, film coated - Oral, Oral, Tablet, film coated
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
, 320.0 mg
, Tablet - Oral, Tablet, Tablet, film coated - Oral, Oral, Tablet, film coated
Gonorrhea
, 320.0 mg
, Tablet - Oral, Tablet, Tablet, film coated - Oral, Oral, Tablet, film coated

Warnings

Gemifloxacin Mesylate Contraindications
Condition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
There are 20 known major drug interactions with Gemifloxacin Mesylate.
Common Gemifloxacin Mesylate Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Amiodarone.
Amitriptyline
Major
Gemifloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Artemether.

Gemifloxacin Mesylate Novel Uses: Which Conditions Have a Clinical Trial Featuring Gemifloxacin Mesylate?

42 active studies are currently exploring the potential of Gemifloxacin Mesylate in treating Gonorrhea, Community Acquired Pneumonia (CAP) and Acute Bacterial Exacerbations of Chronic Bronchitis (ABECB).
Condition
Clinical Trials
Trial Phases
Gonorrhea
14 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 2, Phase 1
Community Acquired Pneumonia (CAP)
1 Actively Recruiting
Not Applicable
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
0 Actively Recruiting
Multidrug resistant Streptococcus pneumoniae infection
0 Actively Recruiting
bacterial rhinosinusitis
0 Actively Recruiting
Urinary Tract Infection (UTI)
25 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable

Gemifloxacin Mesylate Reviews: What are patients saying about Gemifloxacin Mesylate?

5Patient Review
10/28/2007
Gemifloxacin Mesylate for Pneumonia caused by Bacteria
I was diagnosed with pneumonia in my left lung on Wednesday and given this medication. I started taking it that night and by Saturday, I was up cleaning the house! In my opinion, this medicine worked very quickly and efficiently. I did have a little trouble sleeping, but that was the only side effect I experienced.
3.7Patient Review
10/20/2009
Gemifloxacin Mesylate for Bacterial Pneumonia caused by Streptococcus pneumoniae
After taking this medication, I developed large hives that covered my body from my jaw to my knees. Two days after stopping the medication, the hives were still there.

Patient Q&A Section about gemifloxacin mesylate

What generation is Gemifloxacin?

"Gemifloxacin is a fourth generation, oral fluoroquinolone antibiotic. It is used in the therapy of mild-to-moderate respiratory tract infections caused by susceptible organisms." - Anonymous Online Contributor

Unverified Answer

What is Factive 320 mg used for?

"It is thought to work by interfering with the ability of bacteria to make DNA. Gemsifloxacin may also be used for purposes not listed in this medication guide.

This medication is used to treat various bacterial infections. It is classified as a quinolone antibiotic. It works by stopping the bacteria's growth. It is believed to work by interrupting the bacteria's ability to create DNA. This medication may also be used for other purposes not mentioned in this guide." - Anonymous Online Contributor

Unverified Answer

What is gemifloxacin mesylate?

"Gemifloxacin is an antibiotic drug that inhibits bacterial growth. It is of the fluoroquinolone class of drugs, which are broad-spectrum antibiotics. This drug is indicated for the treatment of bacterial infections of the lungs. However, this class of drugs carries a risk of serious or disabling side effects." - Anonymous Online Contributor

Unverified Answer

What is Gemifloxacin for?

"Gemifloxacin is an antibiotic used to treat bronchitis and pneumonia caused by bacterial infections. It belongs to a class of medicines known as quinolone antibiotics. These antibiotics work by killing bacteria or preventing their growth. However, they will not work for colds, flu, or other virus infections." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Gemifloxacin Mesylate

Have you considered Gemifloxacin Mesylate clinical trials? We made a collection of clinical trials featuring Gemifloxacin Mesylate, we think they might fit your search criteria.
Have you considered Gemifloxacin Mesylate clinical trials? We made a collection of clinical trials featuring Gemifloxacin Mesylate, we think they might fit your search criteria.
Have you considered Gemifloxacin Mesylate clinical trials? We made a collection of clinical trials featuring Gemifloxacin Mesylate, we think they might fit your search criteria.
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