Energy Active Product for Fatigue

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Radicle Science

Must not be taking: Anticoagulants, Antidepressants, Antipsychotics, others

Disqualifiers: Pregnancy, Heavy drinking, Cardiac dysfunction, others

Compensation: Varies

Number of Visits: Unknown

Duration: 7 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new product, Energy Active Product, to determine its effectiveness in reducing fatigue compared to a placebo (a look-alike product with no active ingredients). The goal is to assess whether the active product can enhance energy levels and related health outcomes. Ideal participants are adults in the U.S. who believe they could benefit from a significant energy boost. Participants must be willing to take a product without knowing if it is the actual product or a placebo. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could lead to new solutions for fatigue.

Will I have to stop taking my current medications?

Yes, you may need to stop taking certain medications if they have a moderate or severe interaction with the study product ingredients. This includes medications like anticoagulants, antidepressants, and others listed in the exclusion criteria.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that the Energy Active Product has been tested in earlier studies on individuals experiencing fatigue. These studies evaluated its effectiveness in alleviating tiredness and related health issues. So far, the product appears safe, with no major side effects reported in these trials.

For those considering joining a trial, early evidence suggests the treatment is safe. However, ongoing studies aim to confirm this. Always discuss any concerns with the trial team. ^{1 2 3 4 5}

Why are researchers excited about this trial?

The Energy Active Product is unique because it aims to tackle fatigue with a potentially new mechanism of action that differs from standard treatments like stimulants or caffeine-based products. Unlike these traditional options, which often provide only temporary relief or come with side effects like jitteriness, the Energy Active Product may offer sustained energy enhancement without such drawbacks. Researchers are excited because this treatment could provide a more balanced and longer-lasting solution for those struggling with fatigue, potentially improving overall quality of life without the peaks and crashes associated with current options.

What evidence suggests that this trial's treatments could be effective for fatigue?

This trial will compare the Energy Active Product with a placebo control to evaluate its effectiveness in reducing tiredness. Research has shown that the Energy Active Product might help reduce tiredness. Previous studies have examined how health and wellness products can affect tiredness and related health issues. For example, one study found noticeable changes in energy levels throughout the day, suggesting possible benefits for those feeling fatigued. Although specific data on the Energy Active Product remains limited, its focus on boosting energy and managing tiredness appears promising. Early signs suggest it could improve daily energy levels for people dealing with fatigue. ^{3 5 6 7 8}

Who Is on the Research Team?

Susan Hewlings

Principal Investigator

Radicle Science Inc.

Are You a Good Fit for This Trial?

This trial is for individuals experiencing fatigue who are interested in testing the effects of health and wellness products. Specific eligibility criteria have not been provided, but typically participants should be healthy adults willing to follow the study protocol.

Inclusion Criteria

Resides in the United States

Has the opportunity for at least 30% improvement in their primary health outcome

I am at least 21 years old and consent to participate.

Exclusion Criteria

Individuals who report any of the following during screening will be excluded from participation: Report being pregnant, trying to become pregnant, or breastfeeding

Unable to provide a valid US shipping address and mobile phone number

Reports current enrollment in another clinical trial

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive the study product or placebo for the assessment of fatigue and related health outcomes

7 weeks

All assessments are electronic; no in-person visits

Follow-up

Participants are monitored for safety and effectiveness after treatment

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Energy Active Product
• Energy Placebo Control

Trial Overview The study is examining an 'Energy Active Product' against a placebo (a product with no active ingredients) to see if it affects fatigue levels. It's a randomized trial where participants won't know which group they're in, ensuring unbiased results.

How Is the Trial Designed?

Group I: Active product Experimental Treatment 1 Intervention

Energy Active Product

Group II: Placebo control Placebo Group 1 Intervention

Energy Product Control

Who Is Running the Clinical Trial?

Radicle Science

Lead Sponsor

Trials

24

Recruited

46,200+

Citations

1. withpower.com withpower.com/trial/phase-fatigue-8-2025-c243f

Energy Active Product for Fatigue · Info for Participants This trial is for individuals experiencing fatigue who are interested in testing the effects of health and wellness products. Specific eligibility criteria ...

2. patlynk.com patlynk.com/trial/NCT07166523

Radicle Energy™ 24_RCA on Fatigue and Health Outcomes This study aims to explore how certain health and wellness products can affect fatigue and other related health outcomes in adults living in the United ...

3. sciencedirect.com sciencedirect.com/science/article/abs/pii/S0013794423005222

An energy-CP-combined model for predicting the fatigue ... The fatigue prediction life model is built on Fine and Bhat's theory, where the energy efficiency factor is calibrated using experimental data, ...

4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12318978/

Design and validation of an energy level diary for fatigue ... The final diary revealed that morning and evening energy levels of patients with PCS differed significantly, with 49.6 ± 18.6% and 33.4 ± 19.7%, ...

5. clinicaltrials.gov clinicaltrials.gov/study/NCT06879522

Maximizing Energy and Reducing Fatigue in Breast ... This study is testing a program called Maximizing Energy to see if it can help women who have finished breast cancer treatment manage their fatigue.

6. clinicaltrials.gov clinicaltrials.gov/study/NCT07166523

Radicle Energy™ 24_RCA: A Study Assessing the Impact ... Radicle Energy™ 24_RCA: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes.

7. ctv.veeva.com ctv.veeva.com/study/radicle-energy-24-a-study-of-health-and-wellness-products-on-fatigue-and-related-health-outcomes

Radicle Energy 24: A Study of Health and Wellness Products ... A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on fatigue and related health outcomes.

8. clinicaltrials.gov clinicaltrials.gov/study/NCT07036679

Radicle Energy 25: A Study Assessing the Impact of Health ... A Randomized, Double-Blind, Placebo Controlled Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health ...