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What is Fanapt
IloperidoneThe Generic name of this drug
Treatment SummaryIloperidone is a medication used to treat schizophrenia symptoms. It was first researched by Hoechst Marion Roussel Inc. and went through several development phases before being approved by the FDA in 2009. Iloperidone is an atypical antipsychotic and has been marketed and distributed by Novartis since 1998.
Fanaptis the brand name
Fanapt Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fanapt
Iloperidone
2009
37
Approved as Treatment by the FDA
Iloperidone, commonly known as Fanapt, is approved by the FDA for 1 uses including Schizophrenia .Schizophrenia
Helps manage Schizophrenia
Effectiveness
How Fanapt Affects PatientsIloperidone is used to treat schizophrenia and improve cognition. It works by binding to receptors in the brain, including dopamine D2, α adrenergic, serotonin 5-HT2a and dopamine 3 receptors. It also has moderate affinity for dopamine D4, serotonin 5-HT6 and 5-HT7, and norepinephrine NEα1 receptors, and weak affinity for serotonin 5-HT1A, dopamine D1, and histamine H1 receptors.
How Fanapt works in the bodyIloperidone is a medication that works on two types of brain receptors. It blocks dopamine and serotonin receptors, which helps reduce symptoms of certain mental health conditions.
When to interrupt dosage
The suggested measure of Fanapt is contingent upon the recognized condition. The amount of dosage fluctuates, as per the method of delivery (e.g. Kit or Tablet - Oral) featured in the table beneath.Condition
Dosage
Administration
Schizophrenia
1.0 mg, 2.0 mg, 4.0 mg, 6.0 mg, 8.0 mg, 10.0 mg, 12.0 mg, , 13.0 mg
, Oral, Tablet, Tablet - Oral, Kit - Oral, Kit
Warnings
There are 20 known major drug interactions with Fanapt.Common Fanapt Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
Iloperidone may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Iloperidone may increase the antipsychotic activities of Amisulpride.
Aripiprazole lauroxil
Major
Iloperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Iloperidone is combined with Artemether.
Asenapine
Major
Iloperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Asenapine.
Fanapt Toxicity & Overdose RiskTaking this drug may cause side effects such as dizziness, dry mouth, tiredness, blocked nose, low blood pressure when standing, drowsiness, fast heart rate, and weight gain (in 5% or more of patients).
Fanapt Novel Uses: Which Conditions Have a Clinical Trial Featuring Fanapt?
170 active trials are currently evaluating the potential of Fanapt to manage Schizophrenia.Condition
Clinical Trials
Trial Phases
Schizophrenia
175 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Fanapt Reviews: What are patients saying about Fanapt?
5Patient Review
4/4/2016 Fanapt at a dosage of 6mg has been effective in treating my OCD.
4Patient Review
8/11/2014 I'm noticing a definite improvement in my mood, but there's an unfortunate side effect of retrograde ejaculation. I really hope this isn't permanent!
3.7Patient Review
10/20/2012 I switched to Fanapt to try and mitigate the issues of TD I was having with Latuda. It did stop that, but introduced some other problems like lightheadedness and sedation which are on-par with Geodon. This is my fifth medication change; at this point, I don't know how many more options I have.
2.7Patient Review
9/17/2013 I took 12mg and found it hard to concentrate or feel motivated. My libido also tanked, which was really frustrating.
2.3Patient Review
1/4/2016 My blood pressure drops to a dangerously low level with this treatment.
2Patient Review
11/19/2012 This medicine made me very tired and I had no desire for sex. Additionally, I started to grow man boobs and gained a lot of weight in a short period of time. The price is also quite high given that it's been on the market for awhile now.
1.7Patient Review
5/1/2012 I have been taking Fanapt for a few months now, and I am not seeing any benefits for my depression. In fact, the medication has given me urinary incontinence (an issue not listed in the side effects) which apparently affects 10% of users. Additionally, I've noticed moderate memory loss. This may work well for other people, but it has not helped me at all.
1Patient Review
1/16/2013 I experienced a lot of serious side effects while taking this medication, including extreme fatigue, difficulty swallowing, heart palpitations, dizziness, and lightheadedness. Towards the end, I also suddenly developed hypotension which made me faint and unable to walk.
1Patient Review
11/8/2012 I've been taking this medication for over a week now and it's not doing anything to help. If anything, the side effects are worse than before.
Patient Q&A Section about fanapt
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Fanapt an antipsychotic?
"Fanapt (iloperidone) is an antipsychotic medication that is taken to treat schizophrenia."
Answered by AI
What is the drug Fanapt used for?
"This medication is used to treat certain mental/mood disorders (such as schizophrenia). Iloperidone helps you to think more clearly, feel less nervous, and take part in everyday life. It may also help to decrease hallucinations (hearing/seeing things that are not there)."
Answered by AI
Is Fanapt used for bipolar?
"Iloperidone (Fanapt®) is FDA-approved for the treatment of schizophrenia in adults. It has shown clinical efficacy in four- and six-week trials. Iloperidone is not FDA approved for treatment of bipolar disorder or major depressive disorder."
Answered by AI
How effective is Fanapt?
"Fanapt has an average rating of 6.3 out of 10 from a total of 25 ratings on Drugs.com. More than half of reviewers had a positive experience, while 24% reported a negative experience. Reviews may be edited for grammar/spelling or to remove inappropriate language and content."
Answered by AI