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What is Factive
GemifloxacinThe Generic name of this drug
Treatment SummaryGemifloxacin is a type of antibiotic that is used to treat acute exacerbations of chronic bronchitis and mild-to-moderate pneumonia. It comes in pill form and works by blocking the bacteria’s ability to make DNA, which stops the bacteria from growing.
Factiveis the brand name
Factive Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Factive
Gemifloxacin
2003
4
Approved as Treatment by the FDA
Gemifloxacin, otherwise known as Factive, is approved by the FDA for 4 uses like Urinary Tract Infection (UTI) and Community Acquired Pneumonia (CAP) .Urinary Tract Infection (UTI)
Community Acquired Pneumonia (CAP)
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
Multidrug resistant Streptococcus pneumoniae infection
Effectiveness
How Factive Affects PatientsGemifloxacin is an antibiotic used to fight bacteria. It works by attaching to an enzyme in bacteria that helps them replicate and divide. This attachment prevents the bacteria from reproducing. Gemifloxacin is very effective against both types of bacteria, Gram-positive and Gram-negative.
How Factive works in the bodyGemifloxacin kills bacteria by blocking certain enzymes that are needed for the bacteria to replicate, make repairs, and produce new cells.
When to interrupt dosage
The quantity of Factive is contingent upon the diagnosed state, such as Urinary Tract Infection (UTI), Community Acquired Pneumonia (CAP) and bacterial rhinosinusitis. The measure of dosage is contingent upon the mode of delivery, featured in the table hereafter.Condition
Dosage
Administration
bacterial rhinosinusitis
, 320.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
, 320.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Gonorrhea
, 320.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Multidrug resistant Streptococcus pneumoniae infection
, 320.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Urinary Tract Infection (UTI)
, 320.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Community Acquired Pneumonia (CAP)
, 320.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Warnings
Factive ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Factive Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Amiodarone.
Amitriptyline
Major
Gemifloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Artemether.
Factive Novel Uses: Which Conditions Have a Clinical Trial Featuring Factive?
42 active studies are presently underway to explore the potential of Factive in alleviating Gonorrhea, Community Acquired Pneumonia (CAP) and Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB).Condition
Clinical Trials
Trial Phases
Community Acquired Pneumonia (CAP)
1 Actively Recruiting
Not Applicable
Multidrug resistant Streptococcus pneumoniae infection
0 Actively Recruiting
bacterial rhinosinusitis
0 Actively Recruiting
Gonorrhea
1 Actively Recruiting
Not Applicable
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
0 Actively Recruiting
Urinary Tract Infection (UTI)
24 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable
Factive Reviews: What are patients saying about Factive?
5Patient Review
3/26/2010 I found this treatment to be effective and easy to follow. I made sure to drink plenty of water, as directed.
3.7Patient Review
8/27/2010 After taking the last dose of Factive, I woke up to hives all over my body. This has never happened to me before after taking other similar medications (Cipro and Avelox). My doctor informed me that it was a reaction to the Factive and that even though it is similar to Avelox, it is slightly different.
3Patient Review
10/5/2010 In 2005, my doctor put me on a 10-day treatment. However, I developed a terrible rash afterwards and had to go to the ER for steroid treatment. Since then, I've suddenly become allergic to peanuts and peppers--I believe this drug is to blame.
3Patient Review
3/16/2010 This treatment is great. I love how it helps me feel better.
3Patient Review
2/2/2011 I had a terrible reaction to this medication, developing a painful and itchy rash all over my body. I would never recommend it to anyone.
2.7Patient Review
11/7/2010 I had a really terrible reaction to this medicine. Just four days after taking it, I broke out in a rash all over my body. I also got sores on my tongue and a yeast infection. Definitely check reviews before taking any more medicine!
1Patient Review
1/28/2011 I had an extremely severe and uncomfortable rash within two days of taking this medication. I've never had such a reaction to an antibiotic, but Factiv caused me problems for years afterwards. My skin became hyperactive and I constantly suffered from itching and rashes.
1Patient Review
4/28/2011 Factive was a complete nightmare for me. I got a rash all over my body that itched so badly I couldn't sit still. It was honestly one of the worst experiences of my life.
Patient Q&A Section about factive
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does Factive treat?
"Factive is a prescription medication used to relieve the symptoms of pneumonia and chronic bronchitis that has flared up. It may be used on its own or in conjunction with other drugs. Factive is part of a group of drugs known as fluoroquinolones. The safety and effectiveness of this medication has not been established in children."
Answered by AI
What is the medication Gemifloxacin used for?
"Gemifloxacin is used to treat bronchitis and pneumonia caused by bacterial infections. It is classified as a quinolone antibiotic and works by either killing the bacteria or preventing their growth. However, it will not work on illnesses such as colds, flu, or other virus infections."
Answered by AI
Is Factive still available?
"All of the above formulations have been discontinued as of Aug 10, 2022. However, there are still some pharmacies (both online and offline) that might attempt to sell an illegal generic version of Factive. These medications may be counterfeit and potentially unsafe, so please be cautious when purchasing any medication."
Answered by AI
What kind of drug is Factive?
"Factive is an antibiotic that helps fight bacteria in the body. It is generally used to treat infections in the lungs, but can also have serious side effects."
Answered by AI