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What is Epivir
LamivudineThe Generic name of this drug
Treatment SummaryDDC (didanosine) is a medication used to treat HIV-1 and hepatitis B infections. It works by blocking the action of an enzyme called reverse transcriptase, which helps the virus replicate. It is a type of zalcitabine analog, where the 3' carbon in the pentose ring is replaced by a sulfur atom.
Epiviris the brand name
Epivir Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Epivir
Lamivudine
1995
178
Approved as Treatment by the FDA
Lamivudine, otherwise called Epivir, is approved by the FDA for 3 uses which include Chronic Hepatitis B Infection and HIV .Chronic Hepatitis B Infection
HIV
Used to treat Human Immunodeficiency Virus Type 1 (HIV-1) Infection in combination with Abacavir
HIV
Effectiveness
How Epivir Affects PatientsLamivudine is a drug used to treat HIV and hepatitis B. It works by stopping the virus from making copies of itself. When it is activated in the body, lamivudine makes molecules that interfere with the virus’s DNA, making it impossible for it to reproduce. Since lamivudine molecules lack a certain kind of chemical bond, they cannot help the virus create a DNA chain, preventing it from making copies of itself.
How Epivir works in the bodyLamivudine stops viruses from reproducing by preventing them from making copies of their DNA. It works by entering the virus and being changed into an active form. This active form then binds to the virus' DNA and stops it from making more copies.
When to interrupt dosage
The prescribed measure of Epivir is contingent upon the determined condition. The dose fluctuates, according to the technique of delivery featured in the presented table.Condition
Dosage
Administration
HIV
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Chronic Hepatitis B Infection
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Anti-Retroviral Agents
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
treatment failure
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Treatment Naive
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
HIV
150.0 mg, 100.0 mg, , 5.0 mg/mL, 300.0 mg, 10.0 mg/mL, 30.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
There are 20 known major drug interactions with Epivir.Common Epivir Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
Lamivudine may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Lamivudine may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Lamivudine may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Allylestrenol
Minor
Lamivudine may decrease the excretion rate of Allylestrenol which could result in a higher serum level.
Almasilate
Minor
Lamivudine may decrease the excretion rate of Almasilate which could result in a higher serum level.
Epivir Toxicity & Overdose RiskCommon side effects of taking this drug may include headache, nausea, feeling tired or unwell, nasal problems, diarrhea, and coughing.
Epivir Novel Uses: Which Conditions Have a Clinical Trial Featuring Epivir?
Currently, 125 active trials are investigating the potential of Epivir in the management of Chronic Hepatitis B.Condition
Clinical Trials
Trial Phases
treatment failure
0 Actively Recruiting
Anti-Retroviral Agents
0 Actively Recruiting
HIV
147 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Chronic Hepatitis B Infection
7 Actively Recruiting
Phase 3, Phase 2, Phase 1
Treatment Naive
0 Actively Recruiting
HIV
41 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1
Epivir Reviews: What are patients saying about Epivir?
5Patient Review
12/1/20151Patient Review
9/12/2020 It worked for the first few weeks. But then, the side effects started! Hand and foot cramps, back spasms. No sleep for almost 2 months (cat naps), extreme weight loss 18 lbs in 5 weeks. Vision changes, passing out, breathing problems - finally lactic acidosis. Almost deadly to me; no recovery in sight!!
Patient Q&A Section about epivir
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Epivir?
"You may experience a headache, dizziness, nausea, diarrhea, trouble sleeping, cough, tired feeling, or runny or stuffy nose."
Answered by AI
What is Epivir used to treat?
"Lamivudine is a medication used to treat human immunodeficiency virus (HIV) infection in adults and children 3 months of age and older. Lamivudine is also used to treat hepatitis b infection."
Answered by AI
How much does Epivir cost?
"The retail price for 30, 150MG Tablets of Epivir is $249.22. With a SingleCare Epivir coupon, however, you can get 30, 300MG Tablets of generic Epivir for only $49.17."
Answered by AI
What is the generic name for Epivir?
"This drug is available as a generic drug and a brand-name drug. Lamivudine oral solution is used to treat HIV infection in children.
The oral tablet form of lamivudine is used to treat HIV infection and hepatitis b (HBV) infection. Lamivudine is also available in oral solution form, which is used to treat HIV infection in children. Lamivudine is available as a generic drug or under the brand name Epivir."
Answered by AI