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What is Epiduo Forte
AdapaleneThe Generic name of this drug
Treatment SummaryAdapalene is a topical medication used to treat acne vulgaris. It works by reducing inflammation, sebum production and hyperkeratinization of the follicular infundibulum, which is associated with Cutibacterium acnes. While there are other medications that are more effective, Adapalene has a better safety profile. Differin and Epiduo are two brands of Adapalene that have been approved by the FDA. Differin is available as a gel, cream, lotion or solution, while Epiduo is a combination gel of Adapalene and Benzoyl Peroxide.
Adapaleneis the brand name
Epiduo Forte Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Adapalene
Adapalene
1996
71
Effectiveness
How Epiduo Forte Affects PatientsAdapalene helps to prevent new acne and skin inflammation. It works similarly to other retinoid compounds, but is sensitive to sunlight and should be used with sunscreen. Some common side effects reported are redness, flaking, dryness, and a burning or stinging sensation.
How Epiduo Forte works in the bodyAdapalene is used to treat and manage mild to severe acne. It works by binding to receptors in the skin to control the growth of skin cells and reduce inflammation. Adapalene can also inhibit the growth of _Cutibacterium acnes_, the bacteria associated with acne, by reducing the activity of certain immune cells. When used with benzoyl peroxide, a medication with antibacterial properties, the combination can reduce comedones and other inflammatory lesions.
When to interrupt dosage
The proposed dosage of Epiduo Forte is contingent upon the diagnosed condition. The measure of dosage shifts, as per the method of delivery (e.g. Topical or Gel) indicated in the table below.Condition
Dosage
Administration
Acne Vulgaris
0.001 mg/mg, , 0.003 mg/mg, 1.0 mg/mL, 0.1 %, 0.3 %, 45.0 mg/mg, 1.5 mg/mg
, Topical, Cream - Topical, Cream, Gel, Gel - Topical, Lotion, Lotion - Topical, Swab, Swab - Topical, Liquid - Topical, Liquid, Solution, Solution - Topical, Kit
Warnings
Epiduo Forte ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Adapalene may interact with Pulse Frequency
Common Epiduo Forte Drug Interactions
Drug Name
Risk Level
Description
Epiduo Forte Toxicity & Overdose RiskAdapalene is generally safe, although an overdose may cause redness, scaling, and skin discomfort. An acute dose of over 5000 mg/kg has been shown to be safe in rats and mice. No systemic or local toxicity was seen in rats treated with 6 mg/kg/day of 0.3% adapalene.
Epiduo Forte Novel Uses: Which Conditions Have a Clinical Trial Featuring Epiduo Forte?
18 active clinical trials are currently exploring the use of Epiduo Forte for the management of Acne.Condition
Clinical Trials
Trial Phases
Acne Vulgaris
22 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3
Epiduo Forte Reviews: What are patients saying about Epiduo Forte?
5Patient Review
12/26/2020 The main downside to this prescription is that it can cause your skin to itch and burn when you first start using it. But, it's been really effective in clearing up my acne. I only get breakouts around my monthly cycle now, but this medication has made a big difference overall. Plus, one tube lasts me more than a year!
4.7Patient Review
10/18/20154.3Patient Review
11/8/2019 At first, this medication definitely dried out my skin. After a few months, though, my skin seemed to adjust and I saw much better results. My skin is now clearer than it once was, although I do still get the occasional pimple.
3.7Patient Review
11/6/2015 I'm seeing some improvement after two weeks, though there's still quite a ways to go. The side effects have been manageable but annoying; my skin is also looking healthier overall.
3.3Patient Review
12/10/2016 Epiduo forte is fantastic if you don't mind a little bit of temporary discomfort. Every time I use it, my face gets red and dried out; however, the results are always worth it because my face is usually clear by morning! So I recommend this treatment to anyone with similar skin type issues.
3.3Patient Review
12/11/2019 This stuff burns really bad. I can't seem to win whether I use it or not. If you have sensitive skin, I recommend finding something else.
3Patient Review
5/4/2016 This made my face burn and the moisturizer didn't help.
1.7Patient Review
6/27/2017 The pain is unbearable, like acid. My skin is peeling and no amount of moisturizer is helping.
1Patient Review
11/24/2019 If you have sensitive skin, I would recommend avoiding this treatment. Unfortunately, I didn't do my research and now my face is burning, peeling, and itching.
1Patient Review
2/29/2020 Unfortunately, this medication caused more problems than it solved. I developed inflammation, welts, and burning sensations. Do not use this product.
1Patient Review
2/21/2017 This treatment was terrible for me! It dried and burned my skin so badly that even washing my face caused pain. I stopped using it over a week ago and my face is still peeling, hurting, and burning. My doctor told me to only use it every other night, but even with washing it off in the morning and using a thick, heavy facial moisturizer, the burning and pain was too much to tolerate. And on top of that, there was no improvement in my acne. This just overall destroyed all my facial skin.
Patient Q&A Section about epiduo forte
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does Epiduo Forte take to clear acne?
"1/3 of people who used Epiduo Forte for 12 weeks saw their acne improve."
Answered by AI
How long does it take for Epiduo Forte to work?
"Your acne will likely get worse before it gets better when you start using Epiduo (adapalene / benzoyl peroxide). However, after about a month of using the medication daily, your skin should start to show improvement. It's important to be patient though, as it can take up to 12 weeks to see the full effects of the medication."
Answered by AI
Does Epiduo Forte help with acne scars?
"According to the OSCAR study, treating acne early and effectively with Epiduo Forte Gel can reduce the risk of atrophic scars."
Answered by AI
What is Epiduo Forte used for?
"The medication is a combination of adapalene and benzoyl peroxide, which are used to kill acne-causing bacteria and reduce inflammation."
Answered by AI