Enjuvia

moderate Vaginal dryness, severe Dyspareunia, Dyspareunia + 6 more
Treatment
10 FDA approvals
20 Active Studies for Enjuvia

What is Enjuvia

Synthetic Conjugated Estrogens, BThe Generic name of this drug
Treatment SummarySynthetic conjugated estrogens, B tablets are a medication used to treat symptoms related to menopause, such as hot flashes and painful intercourse. The tablets contain a blend of ten different synthetic estrogen derivatives derived from plants. Estrogen is a hormone that is naturally produced by the body and is responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. When a woman stops ovulating, the production of estrogen decreases and can lead to menopausal symptoms. Hormone Replacement Therapy (HRT) can help reduce these symptoms by replacing some of the hormones lost during menopause. Synthetic conjugated est
Enjuviais the brand name
image of different drug pills on a surface
Enjuvia Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Enjuvia
Synthetic Conjugated Estrogens, B
2006
8

Approved as Treatment by the FDA

Synthetic Conjugated Estrogens, B, also known as Enjuvia, is approved by the FDA for 10 uses which include Dyspareunia and moderate Vulvovaginal atrophy .
Dyspareunia
Helps manage moderate Dyspareunia
moderate Vulvovaginal atrophy
Helps manage moderate Vulvovaginal atrophy
Menopause
Helps manage severe Vasomotor Symptoms Associated With Menopause
Hot flashes
Helps manage Menopause
severe menopausal vulvovaginal atrophy
Helps manage severe menopausal vulvovaginal atrophy
severe Dyspareunia
Helps manage severe Dyspareunia
moderate Dyspareunia
Helps manage moderate Dyspareunia
moderate Menopausal Vasomotor Symptoms
Helps manage moderate Menopausal Vasomotor Symptoms
severe Vaginal dryness
Helps manage severe Vaginal dryness
moderate Vaginal dryness
Helps manage moderate Vaginal dryness

Effectiveness

How Enjuvia works in the bodyEstrogen products mimic the hormones that the body naturally produces. These hormones are responsible for female reproductive system development and maintenance, as well as secondary sexual characteristics. Estrogens bind to receptor sites in the body and help regulate the secretion of hormones like LH and FSH. During menopause, the body produces less of these hormones, leading to symptoms like hot flashes, painful intercourse, vaginal dryness, and vulvovaginal atrophy. Hormone Replacement Therapy (HRT) helps reduce these symptoms by introducing synthetic or naturally occurring forms of these hormones back into the body.

When to interrupt dosage

The proposed dosage of Enjuvia relies upon the diagnosed condition, such as Menopause, Menopause and mild Vaginal dryness. The measure of dosage is contingent on the method of delivery (e.g. Tablet or Tablet, film coated) recorded in the table beneath.
Condition
Dosage
Administration
moderate Vaginal dryness
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
severe Dyspareunia
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
Dyspareunia
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
moderate Vulvovaginal atrophy
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
severe Vaginal dryness
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
Hot flashes
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
Menopause
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
moderate Menopausal Vasomotor Symptoms
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral
severe menopausal vulvovaginal atrophy
0.3 mg, 0.45 mg, 0.9 mg, 1.25 mg, , 0.625 mg
, Tablet, film coated, Tablet, film coated - Oral, Oral, Tablet, Tablet - Oral

Warnings

Enjuvia has ten contraindications, and should not be taken in union with the circumstances noted in the following table.Enjuvia Contraindications
Condition
Risk Level
Notes
Deep Vein Thrombosis
Do Not Combine
Pulmonary Embolism
Do Not Combine
Breast Cancer
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Pulmonary Embolism
Do Not Combine
Venous Thrombosis
Do Not Combine
Liver Dysfunction
Do Not Combine
Thromboembolism
Do Not Combine
Breast
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
There are 20 known major drug interactions with Enjuvia.
Common Enjuvia Drug Interactions
Drug Name
Risk Level
Description
Anastrozole
Major
The therapeutic efficacy of Anastrozole can be decreased when used in combination with Synthetic Conjugated Estrogens, B.
Dasabuvir
Major
The risk or severity of liver enzyme elevations can be increased when Synthetic Conjugated Estrogens, B is combined with Dasabuvir.
Exemestane
Major
The therapeutic efficacy of Exemestane can be decreased when used in combination with Synthetic Conjugated Estrogens, B.
Ombitasvir
Major
The risk or severity of liver enzyme elevations can be increased when Synthetic Conjugated Estrogens, B is combined with Ombitasvir.
Ospemifene
Major
The risk or severity of adverse effects can be increased when Synthetic Conjugated Estrogens, B is combined with Ospemifene.

Enjuvia Novel Uses: Which Conditions Have a Clinical Trial Featuring Enjuvia?

16 active clinical trials are assessing the utility of Enjuvia for alleviating moderate Dyspareunia, moderate Vaginal dryness and managing Menopausal symptoms.
Condition
Clinical Trials
Trial Phases
moderate Menopausal Vasomotor Symptoms
0 Actively Recruiting
severe Dyspareunia
0 Actively Recruiting
moderate Vaginal dryness
0 Actively Recruiting
severe Vaginal dryness
0 Actively Recruiting
Dyspareunia
4 Actively Recruiting
Not Applicable
Hot flashes
16 Actively Recruiting
Phase 1, Phase 4, Not Applicable, Early Phase 1, Phase 2
moderate Vulvovaginal atrophy
0 Actively Recruiting
severe menopausal vulvovaginal atrophy
0 Actively Recruiting
Menopause
0 Actively Recruiting

Enjuvia Reviews: What are patients saying about Enjuvia?

5Patient Review
11/15/2012
Enjuvia for "Change of Life" Signs
I had great results with this medicine, but now I'm struggling to find the low dosage pills. I don't want to take more medication than necessary.
5Patient Review
5/10/2013
Enjuvia for "Change of Life" Signs
Enjuvia has been the most effective estrogen treatment that I've taken and believe me, I have tried a lot. Enjuvia has given me my life back!
5Patient Review
6/20/2013
Enjuvia for "Change of Life" Signs
I felt great after taking this medication.
4.7Patient Review
1/2/2015
Enjuvia for "Change of Life" Signs
I had a partial hysterectomy and was on the 1.25 dosage for some time, but I decided that I wanted to stop taking it. Unfortunately, the hot flashes returned almost immediately. Now I am back on a dosage of 0.9 and my only concern is the breast soreness. Will give it another week or so to see if this side effect levels off. Other than that, no mood swings or memory loss. Weight gain is a small price to pay for sweatless nights and no more private summers during the day!
4Patient Review
1/23/2012
Enjuvia for "Change of Life" Signs
Enjuvia .9 has helped somewhat with hot flashes, not entirely, but at this point I don't want to take a higher dose. I have noticed some weight gain.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about enjuvia

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Enjuvia still available?

"is the most recent update on this product. The Enjuvia brand name has been discontinued and if generic versions have been approved, there may be generic equivalents available."

Answered by AI

What type of medication is Enjuvia?

"It also prevents bone loss.

Enjuvia is a synthetic form of estrogen that is used as a treatment for menopausal symptoms such as hot flashes and vaginal dryness. It also prevents bone loss."

Answered by AI

What is Duavive used for?

"Duavive is a medicine used to relieve symptoms like hot flashes that are caused by low blood levels of the female hormone estrogen in women who have gone through menopause."

Answered by AI

What is Enjuvia used for?

"Enjuvia is a combination of ten synthetic estrogens used to replace the estrogen levels that are lowered or lost during menopause. Enjuvia is used after menopause to help treat symptoms of night sweats, hot flashes, flushing, pain with sex, and vaginal dryness, burning, or itching. Currently, it is unknown if Enjuvia is still available."

Answered by AI

Clinical Trials for Enjuvia

Have you considered Enjuvia clinical trials? We made a collection of clinical trials featuring Enjuvia, we think they might fit your search criteria.
Have you considered Enjuvia clinical trials? We made a collection of clinical trials featuring Enjuvia, we think they might fit your search criteria.
Image of University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research Laboratory in Aurora, United States.

MitoQ + Exercise for Menopause-Related Vascular Health

50 - 120
Female
Aurora, CO
This trial tests whether combining moderate aerobic exercise with the antioxidant MitoQ can improve blood vessel function in postmenopausal women who lack estrogen. MitoQ aims to reduce oxidative stress and enhance blood flow by improving mitochondrial function. The study will compare the effects of exercise with MitoQ, exercise alone, and MitoQ alone. MitoQ is a mitochondria-targeted antioxidant that has been studied for its potential to enhance exercise-induced muscle adaptations and improve peak power in untrained middle-aged men.
Phase < 1
Waitlist Available
Paid Trial
University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research LaboratoryKerrie L Moreau, PhD
Have you considered Enjuvia clinical trials? We made a collection of clinical trials featuring Enjuvia, we think they might fit your search criteria.
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