This trial is testing if a lower-energy version of a common glaucoma treatment is as effective as the standard treatment, and if repeating the lower-energy treatment yearly is better than waiting for the treatment to wear off.
- Glaucoma and Ocular Hypertension
2 Primary · 3 Secondary · Reporting Duration: 12, 24, 36, and 48 months
4 Treatment Groups
First Randomization: Standard Energy SLT
1 of 4
Second Randomization: As-Needed Repeat SLT at Initial Energy
1 of 4
First Randomization: Low Energy SLT
1 of 4
Second Randomization: Annual Low Energy Repeat SLT
1 of 4
640 Total Participants · 4 Treatment Groups
Primary Treatment: Low Energy SLT · No Placebo Group · Phase 3
Who is running the clinical trial?
Age 18+ · All Participants · 4 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Who else is applying?
How old are they?
|18 - 65||100.0%|
What site did they apply to?
|New York Eye Surgery Associates||100.0%|
What portion of applicants met pre-screening criteria?
- Realini, Tony, Gus Gazzard, Mark Latina, and Michael Kass. 2021. “Low-energy Selective Laser Trabeculoplasty Repeated Annually: Rationale for the COAST Trial”. Journal of Glaucoma. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/ijg.0000000000001788.
- Anthony Realini 2021. "Clarifying the Optimal Application of SLT Therapy Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04967989.
Frequently Asked Questions
Are there numerous hospitals conducting this clinical trial throughout Canada?
"The current study has 18 sites, which are situated in Reading, Cleveland, Laguna Hills and a few other places. If you want to take part in this trial, try to select the site that is closest to your location so that you won't have to travel far." - Anonymous Online Contributor
What is the study's participant cap?
"Yes. The trial is ongoing and has 18 sites across the country. Currently, they are looking for 640 participants in total." - Anonymous Online Contributor
Does Low Energy SLT have any serious risks for human patients?
"Low Energy SLT has been studied in Phase 3 trials, which means that while there is evidence of efficacy, multiple rounds of data have also supported its safety. As such, our team rates it as a 3." - Anonymous Online Contributor
Are people with the relevant medical conditions able to enroll in this trial today?
"Currently, this trial is open and enrolling patients. The information on clinicaltrials.gov indicates that the study was posted on September 22nd, 2021 and updated as recently as July 12th, 2022." - Anonymous Online Contributor