Doxy 100

Rocky Mountain Spotted Fever, Acinetobacter Infections, Ureaplasma Infections + 61 more

Treatment

93 FDA approvals

20 Active Studies for Doxy 100

Treatment for

Rocky Mountain Spotted Fever

What is Doxy 100

Doxycycline

The Generic name of this drug

Treatment Summary

Doxycycline is an antibiotic used to treat various bacterial infections. It belongs to the tetracycline family and is a less toxic version than other members of the family. Doxycycline can be prescribed for different bacterial infections depending on how sensitive the bacteria is to the drug.

Vibramycin Hyclate

is the brand name

image of different drug pills on a surface

Doxy 100 Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Vibramycin Hyclate

Doxycycline

1967

728

Approved as Treatment by the FDA

Doxycycline, otherwise known as Vibramycin Hyclate, is approved by the FDA for 93 uses such as Primary Syphilis and Upper Respiratory Tract Infection .

Primary Syphilis

Upper Respiratory Tract Infection

Streptococcus Pneumoniae Infections

Staphylococcus (S.) Aureus Infection

Anal chlamydia infection

Communicable Diseases

Clostridium difficile Infection

Klebsiella Infections

Chlamydia Infections

Severe Acne

Intestinal Amebiasis

Chlamydial Urethritis

Genus Chlamydia

Actinomycosis

Secondary Syphilis

Rickettsialpox

Cholera (Disorder)

Campylobacter Infections

Mycoplasma Pneumoniae

Inclusion conjunctivitis

Necrotizing ulcerative gingivostomatitis

Chlamydia Infections

Urethritis

Ureaplasma urethritis

Listeria infection

Urinary Tract Infections

Bacteriological Techniques

Relapsing fever caused by Borrelia recurrentis

Campylobacter Infection

Tick-borne fever

Plasmodium Infections

Skin Infections

Chlamydia trachomatis

Typhus, Endemic Flea-Borne

Communicable Diseases

Chlamydial cervicitis

Haemophilus Influenzae Infections

Calymmatobacterium granulomatis

Lymphogranuloma Venereum

Dysentery, Bacillary

Fever

Gonorrhea

Bartonella Infections

Acne Vulgaris

Q Fever

Acinetobacter Infections

Ureaplasma Infections

Communicable Diseases

Uterine Cervicitis

Tularemia

Typhus infections

Epididymo-orchitis gonococcal

Trachoma

Neisseria Gonorrhoeae Infection

Rocky Mountain Spotted Fever

Bartonella bacilliformis infections

Malaria

Bacterial Infection caused by Enterobacter aerogenes

Relapsing Fever

Yaws

Chancroid

Amebic colitis

Brucellosis

Used to treat Brucellosis in combination with Streptomycin

Recurrent Upper and Lower Respiratory Tract Infections (RTIs)

Plague

Chlamydia trachomatis

Cat-Scratch Disease

Shigella Infection

inhaled anthrax caused by Bacillus anthracis

Pneumococcal Infections

Clostridium Infections

Common Cold

Brucellosis

Used to treat Brucellosis in combination with Streptomycin

Trachoma

Plague

Urethritis

Acinetobacter Infections

Yersinia pestis

Psittacosis

Chlamydia psitacci infection

Ureaplasma Infections

Infection Due to Escherichia Coli

Trachoma inclusion conjunctivitis

Listeriosis

Yaws

Relapsing Fever

Vibrio Cholerae Infection

Disease

Haemophilus ducreyi infection

Tularemia

prophylaxis of Malaria

Respiratory Tract Infections

Granuloma Inguinale

Effectiveness

How Doxy 100 Affects Patients

Doxycycline, like other tetracyclines, stops bacteria from growing by blocking the production of proteins they need. It is effective against a variety of different bacteria and can easily pass through cell membranes. Doxycycline also helps to treat parasites and reduce inflammation in certain skin conditions.

How Doxy 100 works in the body

Doxycycline works by stopping the bacteria from making proteins it needs to survive and function. It does this by binding to the ribosomal subunit and blocking the adding of amino acids to mRNA. Doxycycline also reduces inflammation by preventing calcium-dependent microtubular assembly and lymphocytic proliferation, as well as inhibiting nitric oxide synthase, which is an enzyme that produces an inflammatory signaling molecule.

When to interrupt dosage

The measure of Doxy 100 is dependent on the determined condition, such as Urethritis, Chlamydia trachomatis and Respiratory Tract Infections. The amount of dosage is contingent upon the technique of delivery (e.g. Capsule or Syrup - Oral) as outlined in the table beneath.

Condition

Dosage

Administration

Epididymo-orchitis gonococcal

10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg

, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Capsule, extended release - Oral, Capsule, extended release, Powder - Intravenous, Powder, Powder, for suspension, Syrup, Syrup - Oral, Powder, for suspension - Oral, Kit - Oral, For suspension - Oral, Kit, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, For suspension, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous

Cat-Scratch Disease

Chlamydia Infections

Psittacosis

Relapsing Fever

Bacteriological Techniques

Tularemia

Clostridium difficile Infection

Klebsiella Infections

Haemophilus ducreyi infection

Pneumococcal Infections

Brucellosis

Actinomycosis

Primary Syphilis

Gonorrhea

Secondary Syphilis

Rickettsialpox

inhaled anthrax caused by Bacillus anthracis

Listeriosis

Urinary Tract Infections

Warnings

Doxy 100 Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Doxycycline may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Doxycycline may interact with Pulse Frequency

There are 20 known major drug interactions with Doxy 100.

Common Doxy 100 Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Doxycycline.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Doxycycline.

Alectinib

Major

The metabolism of Alectinib can be decreased when combined with Doxycycline.

Alpelisib

Major

The metabolism of Alpelisib can be decreased when combined with Doxycycline.

Amdinocillin

Major

The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Doxycycline.

Doxy 100 Toxicity & Overdose Risk

The toxic dose of doxycycline for rats is 2000mg/kg, for mice 1870mg/kg, and 500mg/kg for dogs. If someone has overdosed on doxycycline, they should stop taking it and start supportive treatment. Dialysis will not reduce the amount of doxycycline in the blood.

image of a doctor in a lab doing drug, clinical research

Doxy 100 Novel Uses: Which Conditions Have a Clinical Trial Featuring Doxy 100?

34 active investigations are assessing the efficacy of Doxy 100 for Haemophilus Influenzae Infections, Respiratory Tract Infections and Amebic colitis.

Condition

Clinical Trials

Trial Phases

Plague

0 Actively Recruiting

Plague

0 Actively Recruiting

Epididymo-orchitis gonococcal

0 Actively Recruiting

Lymphogranuloma Venereum

0 Actively Recruiting

Gonorrhea

0 Actively Recruiting

Urinary Tract Infections

9 Actively Recruiting

Not Applicable, Phase 4, Early Phase 1

Chlamydia trachomatis

0 Actively Recruiting

Pneumococcal Infections

0 Actively Recruiting

Urethritis

0 Actively Recruiting

Typhus, Endemic Flea-Borne

0 Actively Recruiting

Clostridium difficile Infection

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Chlamydia Infections

0 Actively Recruiting

inhaled anthrax caused by Bacillus anthracis

0 Actively Recruiting

Calymmatobacterium granulomatis

0 Actively Recruiting

Haemophilus Influenzae Infections

0 Actively Recruiting

Chancroid

0 Actively Recruiting

Klebsiella Infections

0 Actively Recruiting

Rosacea

2 Actively Recruiting

Early Phase 1, Phase 2

Rocky Mountain Spotted Fever

0 Actively Recruiting

Doxy 100 Reviews: What are patients saying about Doxy 100?

Patient Review

12/17/2020

Doxy 100 for Lyme Disease

I only took two pills and I feel so much better now.

Patient Review

5/6/2021

Doxy 100 for Sexual Transmitted Disease Exposure from Sexual Assault

I would recommend not taking this drug on an empty stomach. It really helped me and my issues!

Patient Review

12/17/2020

Doxy 100 for Lyme Disease

I only took two pills and I already feel so much better.

Patient Review

5/6/2021

Doxy 100 for Sexual Transmitted Disease Exposure from Sexual Assault

Don't take this on an empty stomach! It really helped me and I would recommend it to others.

4.3

Patient Review

4/22/2021

Doxy 100 for Bacterial Urinary Tract Infection

Though it made me feel awful, this antibiotic was the only one that finally got rid of my long-standing UTI symptoms. If I had to go through the same process again, I would still request this medication.

4.3

Patient Review

10/18/2022

Doxy 100 for Sinus Irritation and Congestion

I'm so grateful to have found an antibiotic that I can take without having any allergic reactions or side effects. It's been really helpful in treating my sinus infection and I'm feeling better already.

4.3

Patient Review

10/18/2022

Doxy 100 for Sinus Irritation and Congestion

It's great to have finally found an antibiotic I can take without having any allergic reactions or side effects. So far, this has been really helping with my sinus infection.

4.3

Patient Review

4/22/2021

Doxy 100 for Bacterial Urinary Tract Infection

This antibiotic was very effective at treating my UTI symptoms; however, the side effects were pretty severe. I'm glad it worked, but I hope there's something else out there that can treat UTIs without making me feel so awful.

Patient Review

11/4/2021

Doxy 100 for Mediterranean Spotted Fever

I was diagnosed with COVID-19 on August 11th, 2021 and prescribed this medication. I saw significant improvements while taking it twice daily as well as steroids. The only downside is that I had to drink a lot of water, but other than that there were no negative side effects.

Patient Review

1/21/2022

Doxy 100 for Bacterial Urinary Tract Infection

I've experienced night sweats and nightmares while on this medication. Has anyone else had similar issues?

Patient Review

11/4/2021

Doxy 100 for Mediterranean Spotted Fever

I was diagnosed with COVID-19 and given this medication. I took it as directed, and had no issues or problems. It worked well for me.

Patient Review

1/21/2022

Doxy 100 for Bacterial Urinary Tract Infection

The only problems I have had that ISNT listed by others is: night sweats and nightmares.....has anyone else experienced this?

3.7

Patient Review

5/10/2022

Doxy 100 for Skin Infection

I've been using this medication to treat my Gover's Disease, which is a really itchy and annoying rash. So far, it's been working well in conjunction with other treatments.

3.7

Patient Review

5/10/2022

Doxy 100 for Skin Infection

I have been diagnosed with Gover's Disease, an itchy upper body rash. I am currently taking this medication along with several salves and lotions. I'm told it can last 6 to 12 months; however, I am hopeful it will end sooner.

3.3

Patient Review

1/28/2022

Doxy 100 for Acute Gonorrhea of the Urethra

I'm currently on day one of a seven-day treatment for an STI. I was surprised to see that some people recommend taking it on an empty stomach, but my doctor specifically told me not to do that or else I'd experience gastrointestinal issues like pain and diarrhea. She also said no dairy products.

3.3

Patient Review

1/28/2022

Doxy 100 for Acute Gonorrhea of the Urethra

I'm on day one of the seven-day treatment for an STI. I was surprised to read that some people take it on an empty stomach, but my doctor specifically told me not to do that or else I'd experience gut problems like diarrhea or pain. Dairy products are also a no-no.

Patient Review

4/23/2022

Doxy 100 for Pneumonia caused by Bacteria

If you take this medication on an empty stomach, you will likely experience nausea and vomiting. I learned this the hard way by taking it first thing in the morning.

Patient Review

4/23/2022

Doxy 100 for Pneumonia caused by Bacteria

I found that if I took this medication on an empty stomach, I would become nauseous and vomit clear liquid for about half an hour.

2.7

Patient Review

3/6/2022

Doxy 100 for Infected Conjunctiva by Chlamydia Trachomatis Bacteria

I completed the dosage as prescribed, but I experienced some nasty side effects. These included nausea, drowsiness and weakness while taking the medication. Now, I'm experiencing muscle soreness and dizziness. I don't even know if the cervicitis is gone yet. I'll have to check with my doctor in a month, but for now I'm still experiencing burning around my urethra after urinating.

2.7

Patient Review

3/6/2022

Doxy 100 for Infected Conjunctiva by Chlamydia Trachomatis Bacteria

I completed the dosage as prescribed, but I experienced some pretty severe side effects. Nausea, drowsiness, and weakness were common while taking the medication. Now, I'm experiencing muscle soreness and dizziness. I don't know if this treatment was effective because I still feel burning around my urethra after urinating.

2.3

Patient Review

11/27/2021

Doxy 100 for Non-Contagious Disease due to Actinomyces Bacteria

I've only been taking this medication for a week, and while it has helped clear up my acne, the side effects are really not worth it. So far I have gotten a sunburn, nausea, headaches, bloating, and a yeast infection.

2.3

Patient Review

11/27/2021

Doxy 100 for Non-Contagious Disease due to Actinomyces Bacteria

It's only been a week, but I can tell this treatment is effective against acne. That being said, the side effects (nausea, headaches, bloating, yeast infection) are really not worth it in my opinion.

Patient Review

1/20/2022

Doxy 100 for Upper Respiratory Infection caused by Pneumococcus

I was prescribed this medication for a sinus infection and took it as directed. After the second dose, I started feeling nauseous and had a fever, diarrhea, and headache. I felt worse than before taking the medication and stopped after just two pills.

Patient Review

1/20/2022

Doxy 100 for Upper Respiratory Infection caused by Pneumococcus

I was prescribed this medication for a sinus infection and took it as directed. However, after the second dose I started feeling nauseous, had a headache, and developed diarrhea. I stopped taking the medication because I felt worse than before I started.

1.7

Patient Review

5/14/2021

Doxy 100 for Bacterial Urinary Tract Infection

I get pins and needles in my fingers from this medication, as well as increased sensitivity to sunlight. I don't know if the benefits are worth the discomfort.

1.7

Patient Review

5/14/2021

Doxy 100 for Bacterial Urinary Tract Infection

I am on 100mg twice daily. I get pins and needle feelings in my fingers from this and the sun hurts badly especially on the extremities (toes, fingers, nose) not sure the side effects are worth taking it. I always feel hot to the touch, feverish even.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about doxy 100

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Doxy 100 mg used for?

"Doxycycline is used to treat bacterial infections. It is a tetracycline antibiotic and stops the growth of bacteria."

Answered by AI

What are the side effects of Doxy 100 mg?

"Reactions may include one or more of the following:

Blistering, peeling, or loosening of the skin
Decreased appetite
Diarrhea, watery and severe, which may also be bloody
Difficulty with swallowing
Feeling of discomfort
Headache
Hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
Hives or welts, itching, or rash"

Answered by AI

Is doxycycline a strong antibiotic?

"Doxycycline is an antibiotic that kills a range of bugs, including bacteria and parasites that are difficult to treat with other antibiotics. These intracellular organisms are hard for most antibiotics to reach."

Answered by AI

Is Doxy 100 and doxycycline same?

"This medicine contains the antibiotic doxycycline and is used to treat a wide range of bacterial infections."

Answered by AI

Clinical Trials for Doxy 100

Image of Children's of Alabama in Birmingham, United States.

Antibiotic Duration for Infections in Children

60 - 17

All Sexes

Birmingham, AL

Infections like pneumonia, skin and soft tissue infection (also called SSTI or cellulitis), and urinary tract infections (UTI) are some of the most common reasons children get admitted to the hospital. All three of these conditions require antibiotics for treatment. Although antibiotics are needed to treat the infection and help children feel better, taking them longer than needed can negatively impact children and their families. Negative impacts include things like the burdens of taking more medications and medication side effects. There are guidelines (instructions) from expert medical organizations that suggest the number of days children need antibiotics, but they give a wide range (between 5 and 14 days). Unfortunately, these guidelines are not based on high-quality studies. National data suggests that doctors often choose on the higher end of this range when writing prescriptions for children in the hospital. Our three caregiver co-investigators, other parents of hospitalized children, doctors, other care providers, and researchers, all believe that additional study is needed to determine the best length of antibiotic treatment that weighs both the benefits and harms of antibiotics. The goal of our study is to understand if 5 total days of antibiotic treatment compared to 10 total days of antibiotic treatment is better for children who have been in the hospital for pneumonia, SSTI, or UTI. We will study this question through a randomized control trial. In other words, half of the children will receive 5-days of antibiotics and the other half will receive 10-days of antibiotics. Children in this study (and their caregivers) will not know how many days of antibiotics they will receive to cure their infection because some children will take a placebo (or a pill without antibiotics in it). Only the pharmacy will know if a child is getting antibiotic or placebo (for days 6-10 of treatment). During the first phase of the trial (feasibility phase), 4 hospitals will enroll children in the study. We plan on enrolling 50 patients during this phase. We are starting with just 4 hospitals, so our study team can create and update our study plans if needed. We will closely review information about how many patients and families agree to participate, and if they have any trouble completing any part of the study. We will also interview families to understand the choice to participate in the study, the choice not to participate in the study, and what it is like to be in the study. During the second study phase, we will enroll 1150 more patients across all 11 hospitals. Families will complete short, daily surveys until the 15th day after they started antibiotics, then a larger survey at day 15, at day 20, and at day 30. These surveys will ask about the child's symptoms and recovery from their illness, how the antibiotics are making them feel, and if they had to go back to their doctor, emergency room, or hospital. The answers to these questions will be combined to measure how well the child did, balancing feeling better and having bad effects from the antibiotics. We will use mathematical tests to determine which antibiotic duration is better for treating these illnesses. We will complete other mathematical tests to see if all children should receive the same length of antibiotics or if certain children should be prescribed shorter courses and others longer courses.

Phase 4

Waitlist Available

New This Month

Children's of Alabama (+9 Sites)

Sunitha V Kaiser, MD, MSc

Have you considered Doxy 100 clinical trials?

We made a collection of clinical trials featuring Doxy 100, we think they might fit your search criteria.

Image of Baylor College of Medicine in Houston, United States.

Educational Tool for Urinary Tract Infections

18+

All Sexes

Houston, TX

Urine culture is the most common microbiological test in the outpatient setting in the United States. Unfortunately, contamination during collection is prevalent and undermines test accuracy, leading to incorrect diagnosis, unnecessary treatment, wasted laboratory resources, and inflated costs. Unnecessary antibiotic treatment increases the risk of developing antimicrobial resistance, one of the most serious threats to patients and public health. The goal of this clinical trial is to test whether a bilingual (English and Spanish) educational intervention, an animated video and pictorial flyer, can reduce urine culture contamination and associated inappropriate antibiotic use in adult patients visiting safety-net primary care clinics. The main questions it aims to answer are: 1. Does providing patients with a bilingual educational intervention reduce urine culture contamination rates? 2. Does the intervention lead to fewer unnecessary urinary antibiotic prescriptions? 3. Does providing patients with a bilingual educational intervention reduce contaminated urinalyses? Researchers will compare patients randomized to receive the educational intervention (video and flyer) to those receiving usual care to see if the intervention improves urine collection accuracy and reduces inappropriate antibiotic use. Participants will watch a short, animated video with step-by-step instructions for proper midstream clean-catch urine (MSCC) collection, receive a pictorial flyer (with stills from the video) reinforcing the instructions, and provide a urine sample for culture. Hypothesis: patients who receive the educational intervention will have: lower urine culture contamination rates (primary outcome), fewer urinary antibiotic prescriptions (secondary outcome), and fewer contaminated urinalyses (secondary outcome). The objectives are to (1) develop educational tools: Create an animated video and pictorial flyer with step-by-step urine collection instructions for women and men, developed through an iterative, stakeholder-engaged process, (2) assess acceptability: Use mixed methods (quantitative surveys and qualitative interviews) to evaluate and refine the tools for usability and cultural/linguistic appropriateness, and (3) test effectiveness: Conduct a randomized controlled trial to assess the intervention's impact on urine contamination rates, antibiotic prescribing, and patient satisfaction.

Waitlist Available

Has No Placebo

Baylor College of Medicine

Larissa Grigoryan, MD, PhD