Diflucan

Cerebral Cryptococcosis, Candidemia, Coccidioidomycosis + 22 more

Treatment

24 FDA approvals

20 Active Studies for Diflucan

What is Diflucan

Fluconazole

The Generic name of this drug

Treatment Summary

Fluconazole, commonly known as Diflucan, is a prescription drug used to treat fungal infections in different parts of the body. It was approved by the FDA in 1990 and belongs to a group of anti-fungal medications that includes ketoconazole and itraconazole. Fluconazole is an effective treatment for yeast infections and can be taken orally, with few side effects. In some cases, it can be taken as a single dose to treat a vaginal yeast infection.

Diflucan

is the brand name

image of different drug pills on a surface

Diflucan Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Diflucan

Fluconazole

1990

379

Approved as Treatment by the FDA

Fluconazole, also called Diflucan, is approved by the FDA for 24 uses which include Candida pneumonia and Candida (fungus) .

Candida pneumonia

Candida (fungus)

Vaginal Candidiasis

Used to treat Vaginal Candidiasis in combination with Miconazole

Pruritus

Used to treat Pruritus in combination with Miconazole

Candidiasis

Systemic candidiasis

Meningitis, Cryptococcal

Coccidioidomycosis

Oropharyngeal Candidiasis

Candida urinary tract infection

Itching

Used to treat Pruritus in combination with Miconazole

Candidiasis, Vulvovaginal

Used to treat Vaginal Candidiasis in combination with Miconazole

Coccidioidomycosis

Urinary tract infection

Candida (fungus)

Peritonitis

Esophageal Candidiasis

Cerebral Cryptococcosis

Yeast Infection

Bone marrow transplant, cytotoxic chemotherapy

Candidemia

Bone Marrow Transplantation

Candidiasis

prophylaxis of Candida Infections

Effectiveness

How Diflucan Affects Patients

Fluconazole is a medication used to treat fungal infections caused by _Candida albicans_, _Candida glabrata_, _Candida parapsilosis_, and _Cryptococcus neoformans_. It works by blocking the growth of fungus and preventing it from adhering to surfaces, thereby treating the infection and its symptoms. Although it is generally effective, some strains of these organisms may be resistant to fluconazole. It is important to test for susceptibility before using fluconazole. There have been some concerns that fluconazole may interfere with hormones in humans, however

How Diflucan works in the body

Fluconazole works by interfering with the production of a certain type of molecule found in fungi. This molecule, called ergosterol, is important for the fungi cell wall. Fluconazole blocks the enzyme that helps turn lanosterol into ergosterol, meaning the fungi cannot make more of the molecule. This leads to a buildup of lanosterol, which weakens the cell wall and halts the growth of the fungus. Resistance to fluconazole can occur if there is a change in the amount or function of the enzyme, or if access to the enzyme is limited. Other reasons for resistance may also exist.

When to interrupt dosage

The suggested measure of Diflucan is dependent upon the identified condition, such as Candida (fungus), Candida intertrigo and Bone Marrow Transplantation. The magnitude of dosage fluctuates, based on the mode of delivery (e.g. Topical or Powder, for solution) stated in the table below.

Condition

Dosage

Administration

Solid Organ Transplant

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candidiasis

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candidiasis, Vulvovaginal

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Urinary tract infection

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Communicable Diseases

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Yeast Infection

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Bone Marrow Transplantation

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Oropharyngeal Candidiasis

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Esophageal Candidiasis

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candidemia

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Coccidioidomycosis

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candida pneumonia

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Pneumonia

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candida (fungus)

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candida intertrigo

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Coccidioidomycosis

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

prophylaxis of moderate Pneumocystis pneumonia

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Itching

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

prophylaxis of Candida Infections

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Candida (fungus)

, 4.0 mg/mL, 10.0 mg/mL, 40.0 mg/mL, 2.0 mg/mL, 50.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 35.0 mg/mL, 140.0 mg/mL, 0.04 mg/mg, 0.01 mg/mg, 50.0 mg/mL

, Injection, solution, Intravenous, Injection, solution - Intravenous, Oral, Powder, for suspension - Oral, Powder, for suspension, Injection, Injection - Intravenous, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution - Intravenous, Solution, Capsule; Cream - Oral; Topical; Vaginal, Oral; Topical; Vaginal, Capsule; Cream, Oral; Topical, Capsule; Cream; Kit - Oral; Topical, Capsule; Cream; Kit, Powder, for solution, Powder, for solution - Oral, Solution - Oral, Solution - Topical, Topical, Capsule; Cream - Oral; Topical

Warnings

Diflucan Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Fluconazole may interact with Pulse Frequency

There are 20 known major drug interactions with Diflucan.

Common Diflucan Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The serum concentration of Abemaciclib can be increased when it is combined with Fluconazole.

Abrocitinib

Major

The metabolism of Abrocitinib can be decreased when combined with Fluconazole.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Fluconazole.

Acetylsalicylic acid

Major

The metabolism of Acetylsalicylic acid can be decreased when combined with Fluconazole.

Alectinib

Major

The metabolism of Alectinib can be decreased when combined with Fluconazole.

Diflucan Toxicity & Overdose Risk

The lethal dose of fluconazole in rats is 1271mg/kg. Overdosing on fluconazole can cause hallucinations, confusion, and paranoia. In case of overdose, medical treatment such as gastric lavage and hemodialysis may be needed. People with existing liver problems should use caution when taking fluconazole as it can cause serious liver damage. There are no known risks of using fluconazole during pregnancy, although high doses may cause birth defects. Breastfeeding mothers should also use caution as fluconazole is secreted in breastmilk.

image of a doctor in a lab doing drug, clinical research

Diflucan Novel Uses: Which Conditions Have a Clinical Trial Featuring Diflucan?

37 active trials are underway to assess the efficacy of Diflucan in treating Urinary tract infection, Cerebral Cryptococcosis and Coccidioidomycosis.

Condition

Clinical Trials

Trial Phases

prophylaxis of moderate Pneumocystis pneumonia

0 Actively Recruiting

HIV

155 Actively Recruiting

Phase 2, Phase 1, Phase 3, Not Applicable, Phase 4, Early Phase 1

Urinary tract infection

0 Actively Recruiting

Candida (fungus)

0 Actively Recruiting

Pneumonia

0 Actively Recruiting

Bone marrow transplant, cytotoxic chemotherapy

0 Actively Recruiting

Candida (fungus)

0 Actively Recruiting

Peritonitis

0 Actively Recruiting

Cerebral Cryptococcosis

1 Actively Recruiting

Phase 2, Phase 3

Candida intertrigo

0 Actively Recruiting

Oropharyngeal Candidiasis

0 Actively Recruiting

Bone Marrow Transplantation

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Candidemia

4 Actively Recruiting

Phase 3, Phase 2

Candida pneumonia

0 Actively Recruiting

Esophageal Candidiasis

0 Actively Recruiting

prophylaxis of Candida Infections

0 Actively Recruiting

Yeast Infection

0 Actively Recruiting

Itching

2 Actively Recruiting

Phase 3, Not Applicable

Candidiasis

0 Actively Recruiting

Diflucan Reviews: What are patients saying about Diflucan?

5

Patient Review

9/6/2016

Diflucan for Yeast Infection of Vagina and Vulva

Diflucan is incredibly effective for me and has completely gotten rid of my yeast infection symptoms within 24 hours. It's also much easier to use than those messy over-the-counter creams. I haven't experienced any side effects, either.

5

Patient Review

8/6/2018

Diflucan for Yeast Infection of Vagina and Vulva

This is the only medication that has helped with my yeast infections. Those over-the-counter ones actually cause irritation and make it worse. I have no side effects from this pill, which is great.

5

Patient Review

3/27/2018

Diflucan for Yeast Infection of Vagina and Vulva

Amoxicillin led to me getting a yeast infection, but this treatment cleared it right up.

4.7

Patient Review

12/15/2016

Diflucan for Yeast Infection of Vagina and Vulva

Diflucan seems to work great, though it gives me a slight headache. I took the first dose and most of my discharge and itching cleared up within a day. Took the second dose five days later as directed, and hoping it will take care of the rest of the discharge. This is my second yeast infection, and I definitely prefer this pill to messy creams. Advil takes care of any headaches.

4.7

Patient Review

7/25/2015

Diflucan for Treatment for Prevention of Vulvovaginal Yeast Infection

I found this medication to be extremely effective, especially in comparison to over-the-counter options. I've never experienced any negative side effects, although I understand that some may occur with prolonged use.

4

Patient Review

2/27/2016

Diflucan for Candida Species Yeast Infection of Abdominal Cavity Lining

This medication cleared up my infection, but unfortunately I'm now dealing with uncomfortable swelling and heartburn.

3.7

Patient Review

4/6/2018

Diflucan for Candida Fungus Infection of Mouth, Skin, Nails or Vagina

I was prescribed this medication for a yeast infection that I got from taking hormone medications. I took 100mg once a day for a week, as directed. However, after finishing the course of medicine, my hair started falling out in clumps. Additionally, my hairline felt sore - like it does when you wear a ponytail for too long. Overall, I don't think I would ever take this medication again.

3

Patient Review

7/6/2022

Diflucan for Thrush

I'm one of the lucky ones who didn't experience any negative side effects. That being said, I don't think this medication did anything to help with my candida.

2.7

Patient Review

10/21/2018

Diflucan for Yeast Infection of Vagina and Vulva

I was put on Augmentin and then got a yeast infection, so the doctor prescribed this. Unfortunately, it's made me really uncomfortable. I had diarrhea for two days straight and major chills last night. I'm still hoping the yeast infection clears up soon.

2.7

Patient Review

9/29/2016

Diflucan for Candida Species Yeast Infection of Abdominal Cavity Lining

Unfortunately, I had a really terrible experience with the side effects of this medication. I wouldn't wish them on anyone.

1.7

Patient Review

10/9/2015

Diflucan for Candidiasis Yeast Infection that Spreads Throughout Body

Took the medication and developed large, unsightly swellings on my lower lip and upper right eyelid. The lip swelling turned black and has left permanent scarring. Not happy with this at all.

1.3

Patient Review

7/31/2018

Diflucan for Yeast Infection of Vagina and Vulva

Day 3 and I'm not seeing any improvement. If anything, it's gotten worse. Augmentin was the original cause of this problem for me; however, I have been eating yogurt twice a day in an effort to improve things.

1

Patient Review

12/20/2021

Diflucan for Skin Infection marked by Ulcers - Cutaneous Leishmaniasis

I had dark marks on my face for months, and this medication did nothing to help them. In fact, I developed blisters on my lips from using it. Needless to say, I won't be using this again.

1

Patient Review

6/28/2022

Diflucan for Presence of Candida Species Yeast in the Blood

I felt incredibly nauseous after taking just one pill, and I also had muscle spasms in my leg during the night. Needless to say, I won't be taking this medication again.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about diflucan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What infections are treated with Diflucan?

"There are many different types of skin infections, marked by different symptoms. Cutaneous leishmaniasis results in ulcers, while ringworm of the scalp causes bald spots. Candida yeast infection of the abdominal cavity lining can cause diarrhea, while ringworm of the hand can cause cracking and peeling of the skin. Ringworm of the groin area can cause intense itching, while athlete's foot causes burning and redness. Ringworm of the body can cause a rash, while tinea versicolor is a fungal infection of the skin that can cause discoloration."

Answered by AI

How long does Diflucan one take to work?

"Fluconazole 150 mg capsules help to treat vaginal yeast infections by killing the Candida yeast. They typically start working within one day, but it may take up to a week for symptoms to completely go away."

Answered by AI

What happens after you take a Diflucan?

"Fluconazole is an antifungal medication that kills the fungus causing the infection. The medicine works by making holes in the cell membrane of the fungus, causing its contents to leak out. This kills the infection and allows the symptoms to improve."

Answered by AI

What is Diflucan prescribed for?

"Fluconazole is used to prevent and treat fungal and yeast infections. It belongs to a class of drugs known as azole antifungals. These drugs work by stopping the growth of certain types of fungus."

Answered by AI

Clinical Trials for Diflucan

Image of New Jersey Community Research Initiative in Newark, United States.

AI-DBT for Suicide Prevention in HIV/AIDS

18+
All Sexes
Newark, NJ

One in four older persons living with HIV/AIDS (PLWHA) report at least one suicide attempt in their lifetime, and the risk for death by suicide is 100 times higher in PLWHA than in the general population. Currently, there are no behavioral interventions that specifically address suicide prevention for older PLWHA, despite their unique biopsychosocial and structural risk factors. Through this work, investigators will adapt Dialectical Behavior Therapy, an evidence-based intervention for suicide prevention, for patients with PLWHA to be delivered by an AI-powered conversational Agent developed by our industry partner, Empower Health. Investigators will then pilot test the feasibility, usability, acceptability and preliminary efficacy to improve self-efficacy to manage negative emotions in n=50 older adults living with HIV/AIDS.

Recruiting
Has No Placebo

New Jersey Community Research Initiative (+1 Sites)

Elissa Kozlov, PhD

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

Image of George Washington University Emergency Department in Washington D.C., United States.

Decision Support Tool for HIV Prevention

18+
All Sexes
Washington D.C., United States

This project will explore the development of a personalized decision support tool to assist with pre-exposure prophylaxis (PrEP) initiation and persistence among patients identified in the emergency department (ED) and urgent care settings as PrEP eligible. First, the investigators will use a sequence of validated implementation science methodologies to develop and validate a decision support tool designed to optimize PrEP persistence by strengthening self-efficacy by addressing the multifaceted medical and social needs of the individual patient. The investigators will then test the preliminary effectiveness of this tool through a pilot stepped wedge implementation trial in two EDs and an urgent care in Baltimore, MD and Washington, DC among 120 PrEP eligible patients to determine PrEP initiation, linkage to care, persistence, and adherence rates.

Phase 1
Waitlist Available

George Washington University Emergency Department (+1 Sites)

Image of The University of Alabama at Birmingham in Birmingham, United States.

Behavioral vs Mindfulness Treatments for Insomnia in HIV

50 - 99
All Sexes
Birmingham, AL

The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV. The main questions it aims to answer are: What are the effects of BBTI vs BMT on self-reported and observed sleep outcomes in older adults with HIV and insomnia up to 1-year post-intervention? What are the effects of BBTI vs BMT on self-reported and observed cognitive comes in older adults with HIV and insomnia up to 1-year post-intervention? What is the association between Alzheimer's Disease biomarkers and sleep and cognitive outcomes in older adults with HIV receiving BBTI vs BMT? Participants will: * Complete 4 weeks of telephone-delivered BBTI or BMT * Attend baseline, post-intervention, and 1-year post in-person visits for sleep and cognitive assessments * Have blood collected at all three time points

Waitlist Available
Has No Placebo

The University of Alabama at Birmingham (+1 Sites)

Dr. Shameka L Cody, PhD, AGNP-C, PMHNP-BC, FAAN

Have you considered Diflucan clinical trials?

We made a collection of clinical trials featuring Diflucan, we think they might fit your search criteria.
Go to Trials
Image of Los Angeles General Medical Center in Los Angeles, United States.

Decision Support Tool for HIV Treatment

18+
All Sexes
Los Angeles, CA

This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as antiretroviral therapy (ART), can be complex to manage because the right regimen depends on many factors-such as drug resistance, other health conditions, and medication schedules. Many people with HIV are cared for by general clinicians who may not have access to HIV specialists, which can make treatment decisions more challenging. In this study, healthcare providers will use patient cases to compare standard HIV treatment resources with a new clinical decision support tool that gives evidence-based ART recommendations at the point of care. The investigators hypothesize that using the tool will help providers select treatment plans that better match clinical guidelines, make decisions faster, reduce mental effort, and increase overall satisfaction with the prescribing process.

Waitlist Available
Has No Placebo

Los Angeles General Medical Center

Hayoun Lee, PhD

Image of University of North Carolina in Chapel Hill, United States.

MGD020 + MGD014 for HIV

18 - 65
All Sexes
Chapel Hill, NC

This research study aims to find out how safe and well tolerated the experimental study drugs are when given to persons with HIV (PWH) taking antiretroviral therapy (ART). The study treatments are MGD014 and MGD020, which are two antibodies developed specifically for HIV, and Vorinostat, an oral medication to help expose HIV in cells to the antibodies. The study will measure the impact of study treatment on non-active HIV in cells, and how long MGD014 and MGD020 stay in the body after they are given. In this study, participants will be randomly assigned to one of three groups. All participants receive MGD014 and MGD020, given sequentially as infusions through an IV for 4 doses. Participants in one group (group A) receive only MGD014 and MGD020. Participants in another group (group B) will stop taking their ART therapy for up to 8 weeks (a temporary treatment interruption (TTI)) while receiving MGD014 and MGD020. Participants in the third group (group C) receive Vorinostat in addition to MGD014 and MGD020. Total time of participation is about 8 months and involves 13 or 18 visits, depending on group assignment.

Phase 1
Recruiting

University of North Carolina

Cynthia L. Gay, MD

Image of Center on Substance Use and Health in San Francisco, United States.

CHAMPION Intervention for Pre-exposure Prophylaxis Adherence

18 - 40
Male
San Francisco, CA

The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use disorder (MUD). The CHAMPION intervention combines two mHealth tools-PrEPAPP and CBT4CBT-to address both HIV prevention and MUD treatment needs in this population. The study's specific aims are: * To evaluate the feasibility and acceptability of the CHAMPION intervention based on treatment retention and engagement rates. * To examine the preliminary efficacy the CHAMPION intervention to improve PrEP adherence, as measured by dried blood spot (DBS) tests compared to the waitlist control group.

Waitlist Available
Has No Placebo

Center on Substance Use and Health

Glenn-Milo Santos, PhD, MPH

Have you considered Diflucan clinical trials?

We made a collection of clinical trials featuring Diflucan, we think they might fit your search criteria.
Go to Trials

Have you considered Diflucan clinical trials?

We made a collection of clinical trials featuring Diflucan, we think they might fit your search criteria.
Go to Trials