Diclofenac Sodium And Misoprostol

Contusions, Pain, Photophobia + 54 more

Treatment

10 FDA approvals

20 Active Studies for Diclofenac Sodium And Misoprostol

What is Diclofenac Sodium And Misoprostol

Diclofenac

The Generic name of this drug

Treatment Summary

Diclofenac is a type of non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It works by blocking the enzymes that produce prostaglandins, which are chemicals that contribute to inflammation and pain signaling. Diclofenac is a common first-line treatment for many types of acute and chronic pain. It is often prescribed in combination with misoprostol to help prevent NSAID-induced ulcers in the stomach. Diclofenac was approved by the FDA in 1988 under the brand name Voltaren.

Voltaren

is the brand name

image of different drug pills on a surface

Diclofenac Sodium And Misoprostol Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Voltaren

Diclofenac

1988

767

Approved as Treatment by the FDA

Diclofenac, also called Voltaren, is approved by the FDA for 10 uses including Osteoarthritis of the Knee and Pain .

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Pain

Helps manage Pain

Postoperative Inflammatory Response

Chronic Pain

Helps manage Pain

Osteoarthritis (OA)

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Stomach Ulcer

Used to treat develop NSAID-induced gastric ulcers in combination with Misoprostol

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Osteoarthritis

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Rheumatoid Arthritis

Cataract Surgery

Effectiveness

How Diclofenac Sodium And Misoprostol Affects Patients

Diclofenac helps reduce pain and fever by reducing inflammation. Unfortunately, it also reduces the amount of protective mucus produced in the stomach, increasing the risk of an ulcer.

How Diclofenac Sodium And Misoprostol works in the body

Diclofenac works by blocking the production of prostaglandins, molecules involved in pain and inflammation. In the body, prostaglandins activate receptors in the nerves that make them more sensitive to pain. They also cause blood vessels to widen and attract white blood cells to sites of inflammation. Diclofenac stops this process and reduces inflammation. It also dampens nerve sensitivity and prevents fever by stopping prostaglandins from activating neurons responsible for heat regulation.

When to interrupt dosage

The proposed dose of Diclofenac Sodium And Misoprostol is determined by the diagnosed disorder, like Joint Pain, Postoperative Inflammatory Response and Osteoarthritis (OA). The quantity of dosage varies, conforming to the protocol of delivery (e.g. Cream; Kit; Solution or Kit; Oil; Solution / drops) mentioned in the following table.

Condition

Dosage

Administration

Contusions

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Photophobia

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Postoperative

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Radiculopathy

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Cataract Surgery

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Postoperative Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Postoperative Inflammatory Response

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Rheumatoid Arthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Rheumatism

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Conjunctivitis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Acute Coryza

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Osteoarthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

radial keratotomy

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Actinic Keratosis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Arthralgia

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, Tablet - Oral, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Tablet, extended release - Oral, Tablet, extended release, Suppository, Rectal, Suppository - Rectal, Solution - Topical, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated, Tablet, sugar coated - Oral, Injection, solution, Intravenous, Injection, solution - Intravenous, Capsule - Oral, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system, Drug delivery system - Topical

Warnings

Diclofenac Sodium And Misoprostol Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Heart failure

Do Not Combine

Crohn's Disease

Do Not Combine

recent history of anal bleeding

Do Not Combine

Hemorrhagic Disorders

Do Not Combine

Gastritis

Do Not Combine

inflammatory lesions of the Rectum

Do Not Combine

active Gastrointestinal Bleeding

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

active Gastrointestinal Perforation

Do Not Combine

Duodenal Ulcer

Do Not Combine

Coronary Artery Bypass Grafting

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Ulcerative Colitis

Do Not Combine

Liver Diseases

Do Not Combine

Stroke

Do Not Combine

Third trimester of pregnancy

Do Not Combine

Hematochezia

Do Not Combine

Kidney Failure

Do Not Combine

Kidney Failure

Do Not Combine

Anus

Do Not Combine

Ulcer

Do Not Combine

damaged skin

Do Not Combine

Gastric ulcer

Do Not Combine

Peptic Ulcer

Do Not Combine

Hyperkalemia

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Diclofenac may interact with Pulse Frequency

There are 20 known major drug interactions with Diclofenac Sodium And Misoprostol.

Common Diclofenac Sodium And Misoprostol Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Diclofenac.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Diclofenac.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Diclofenac.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Diclofenac.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Diclofenac.

Diclofenac Sodium And Misoprostol Toxicity & Overdose Risk

Overdosing on Voltaren can lead to symptoms such as fatigue, nausea, vomiting, upper abdominal pain, and bleeding from the digestive tract. In rare cases, patients may experience high blood pressure, kidney damage or failure, hypoventilation, or coma. Treatments for Voltaren overdose include inducing vomiting and activated charcoal, as long as the overdose occurred within the last 4 hours.

Diclofenac Sodium And Misoprostol Novel Uses: Which Conditions Have a Clinical Trial Featuring Diclofenac Sodium And Misoprostol?

491 active trials are underway to investigate the potential of Diclofenac Sodium and Misoprostol in reducing Inflammation, facilitating argon laser trabeculoplasty, and managing Osteoarthritis of the Knee.

Condition

Clinical Trials

Trial Phases

Inflammation

56 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3, Phase 4

Osteoarthritis of the Knee

77 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Chronic Pain

124 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Rheumatoid Arthritis

58 Actively Recruiting

Not Applicable, Phase 3, Phase 2, Phase 1, Phase 4

Postoperative Pain

20 Actively Recruiting

Phase 4, Phase 2, Phase 1, Phase 3, Not Applicable

Dysmenorrhea

1 Actively Recruiting

Not Applicable

Muscle Pain

3 Actively Recruiting

Phase 4, Not Applicable, Phase 2

Conjunctivitis

0 Actively Recruiting

Musculoskeletal System

1 Actively Recruiting

Not Applicable

corneal refractive surgery

0 Actively Recruiting

Postoperative Inflammatory Response

0 Actively Recruiting

Photophobia

3 Actively Recruiting

Not Applicable

Pain

3 Actively Recruiting

Not Applicable

Stomach Ulcer

0 Actively Recruiting

Rheumatism

0 Actively Recruiting

Juvenile arthritis

8 Actively Recruiting

Phase 2, Not Applicable, Phase 3

radial keratotomy

0 Actively Recruiting

Joints

0 Actively Recruiting

Pericarditis

2 Actively Recruiting

Phase 2, Phase 3

Acute Coryza

0 Actively Recruiting

Diclofenac Sodium And Misoprostol Reviews: What are patients saying about Diclofenac Sodium And Misoprostol?

5

Patient Review

7/30/2020

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

Diclofenac is essential for me to be able to walk without pain in my feet. I have to drink lots of fluids and get my kidney function checked regularly in order to keep taking it.

5

Patient Review

5/17/2017

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

This medication is the only one that has been able to effectively manage my arthritis symptoms. I take two a day, and by 3 PM I start to feel pain and stiffness in my joints. The second pill really helps protect my stomach from the diclofenac. Without this medication, I am in severe pain within 24 hours.

5

Patient Review

8/17/2020

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

Diclofenac Sodium has done wonders for my osteoarthritis pain. I was struggling to even get out of my car before, and now after taking this medication (with very few side effects), I can finally live my life again! Just be sure to drink lots of fluids when you take it.

4

Patient Review

8/9/2016

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

I had frozen shoulder and after taking three of this tablet i got cured, i am so amazed !! I only used it for three days, but i had diarrheas and stomach upset after using this pill.

3.7

Patient Review

5/14/2011

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

It takes about an hour for me to start feeling relief from this medication, and that relief lasts for around 14 hours. After that, the pain comes back.

3.7

Patient Review

10/28/2010

Diclofenac Sodium And Misoprostol for Rheumatic Disease causing Pain & Stiffness in Backbone

This treatment lessened the pain but didn't make it go away entirely.

3.3

Patient Review

10/13/2011

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

I haven't seen a ton of improvement while taking this drug, and the side effects are pretty unpleasant.

3.3

Patient Review

3/2/2011

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

I experienced stomach pain and heartburn after taking this medication.

3

Patient Review

2/26/2012

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

The side effects of this medication were unbearable, so I stopped taking it.

2

Patient Review

11/11/2010

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

Unfortunately, I had to stop using this medication because the stomach pain it caused was too severe.

2

Patient Review

1/31/2011

Diclofenac Sodium And Misoprostol for Rheumatic Disease causing Pain & Stiffness in Backbone

I'm not sure how much of this I should be taking.

2

Patient Review

2/10/2013

Diclofenac Sodium And Misoprostol for Rheumatic Disease causing Pain & Stiffness in Backbone

I took this medication twice a day for two weeks and saw very minimal pain relief.

1

Patient Review

1/9/2011

Diclofenac Sodium And Misoprostol for Osteoarthritis and High Risk of Developing Gastric Ulcers

I was absolutely miserable while taking this drug. I couldn't keep anything down and felt incredibly weak.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about diclofenac sodium and misoprostol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How often can you take misoprostol and diclofenac?

"A typical dose of diclofenac is 50 mg taken 3-4 times per day, with 200 mcg of misoprostol."

Answered by AI

Is diclofenac a strong painkiller?

"Diclofenac is stronger than ibuprofen and should be taken every two or three hours. To effectively treat pain from arthritis, ibuprofen usually needs to be taken in larger doses."

Answered by AI

Does diclofenac misoprostol make you sleepy?

"The following effects may also occur: nausea, heartburn, gas, upset stomach, drowsiness, and dizziness. If any of these effects last or worsen, tell your doctor or pharmacist."

Answered by AI

How do I take diclofenac misoprostol?

"Adults should take one tablet of Arthrotec 50 three or four times a day. Your doctor may adjust your dose as needed and tolerated. Some patients who cannot tolerate the usual dose can be given Arthrotec 75 twice a day or Arthrotec 50 twice a day."

Answered by AI

Clinical Trials for Diclofenac Sodium And Misoprostol

Image of University Center for Ambulatory Surgery in Somerset, United States.

Infusion Pump for Postoperative Pain

18+
All Sexes
Somerset, NJ

This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period.. Patients 18 years or older undergoing ACL reconstruction, open shoulder labrum or rotator cuff surgery, arthroscopic rotator cuff repair, proximal or distal patellar realignment surgery, open knee arthrotomy cases (i.e. inside out meniscus repair, osteochondral allograft transplantation (OCA), meniscal allograft transplantation (MAT)) at University Center for Ambulatory Surgery, LLC (UOA) will be reviewed for eligibility. Once identified, potential study subjects will be asked whether they are interested in participating in the project. If the patient agrees, the subject will be given the informed consent to read and sign. Objectives: The primary objective is to compare the effectiveness of postoperative infusion pain pump versus preoperative nerve block in reducing visual analog pain scores/numerical pain rating scale (VAS/NPRS) in the postoperative period. The second objective is to evaluate the requirement of narcotic and non-narcotic analgesic medications between the two groups. Hypotheses: Use of continuous infusion pain pump or single shot peripheral block will result in similar post-operative pain control after outpatient sports medicine surgical cases.

Phase 4
Recruiting

University Center for Ambulatory Surgery

Image of Montana State University in Bozeman, United States.

Haskap Berries for Exercise Performance Recovery

18 - 35
All Sexes
Bozeman, MT

The purpose of this clinical trial is to determine how certain food items affect oxidative stress, inflammation, and performance recovery from exercise induced muscle damage in a resistance trained population. The main questions The investigators aim to answer are the following: * Do Haskaps speed the recovery of oxidative stress and inflammation markers after an intense lower body workout in resistance trained adults? * Do Haskaps speed the recovery of performance measures after an intense lower body workout in resistance trained adults? * The data collected in this investigation may also be used to ask additional questions not yet identified. For example, the investigators may use the stored samples to evaluate how the blood metabolites of participants differ before and after intense exercise. These additional questions are called secondary analyses. Please note that no genetic analysis will be conducted and racial and ethnic differences among participants will not be used in any secondary analyses. Researches will compare Haskap juice to a color, flavor and carbohydrate matched placebo to see if Haskaps speed recovery in inflammation, oxidative stress and performance. * Participants will be asked to drink either Haskap juice or placebo and follow a low polyphenolic diet * Participants will perform an intense resistance workout * Participants will have their blood drawn before and after the workout * Performance will be analyzed at 24, 48 and 72 hours after the workout

Recruiting
Paid Trial

Montana State University

Mary P Miles

Image of University of North Carolina at Chapel Hill in Chapel Hill, United States.

Pain Medicines for Period Pain in Crohn's Disease

18 - 44
Female
Chapel Hill, NC

The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's disease. The goal of this study is to identify any challenges in running a larger study. The investigators will track how many people sign up for the study, how well participants follow the study plan, how many people stay in the study, and whether they are able to complete all the study activities, such as taking the medication, submitting samples, and filling out surveys. During the study, participants will undergo a screening visit that includes a blood draw, physical exam, pregnancy test, stool testing, and complete surveys about Crohn's disease and menstrual cycles. Once this visit is complete, the rest of the study will occur at home. Participants will be assigned to take either ibuprofen or acetaminophen to help treat period cramps for four menstrual cycles in a row. Participants will take ibuprofen for two cycles and acetaminophen for two cycles. Participants will know which medication is being taken at any given time, but the order in which they take the medications will be randomly assigned. Before each menstrual cycle, participants will submit a stool sample and fill out a short (\<1 minute) electronic survey. When participants develop period cramps, they will take the assigned medication for three days and fill out short (\<1 minute) electronic surveys about their cramps. After participants finish taking the medication for three days, they will submit another stool sample and fill out two more short (\<1 minute) electronic surveys. After have completing this process for four menstrual cycles, a remote interview with a researcher to give feedback on the study will be conducted.

Waitlist Available
Has No Placebo

University of North Carolina at Chapel Hill

Erica J Brenner, MD, MSCR

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

Have you considered Diclofenac Sodium And Misoprostol clinical trials?

We made a collection of clinical trials featuring Diclofenac Sodium And Misoprostol, we think they might fit your search criteria.
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Image of Byers Eye Institute in Palo Alto, United States.

LLM-Based Education for Cataract Surgery

18+
All Sexes
Palo Alto, CA

Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance. Other "premium" lenses have various benefits such as reducing the need for glasses but usually require out-of-pocket costs. The combined busy outpatient clinic and complexity of artificial lens choices in the ever-changing world of cataract surgery tends to lead patients confused about their available lens options. There is an abundance of educational material present in premium lenses, however these are limited by accessibility and are standardized at single educational levels. Therefore in the present study, we want to test whether giving patients a short LLM powered AI-guided explanation from Custom GPT from OpenAI of lens options prior to their consultation with their doctor can improve visit efficiency, physician explanation and patient understanding of lens options. We will compare two groups: standard of care versus standard of care plus AI education. The LLM in this study is intended to provide supplemental information about premium intraocular lens(IOLs) options to study participants, and is no means supposed to replace a health care professional in the diagnosis, cure, treatment, and/or mitigation of disease. Study is analogous to giving a verified health pamphlet to a patient for them to view and learn different IOL options, in other words, facilitating patient understanding of their options. The LLM will be trained by several health care professionals and MD specialists to provide sufficient instructions. Sources will include verified online resources and MD information. The investigators hope to learn if a large language model-based educational tool can improve visit efficiency, physician explanation and patient understanding of intraocular lens options. New knowledge of this study could guide how cataract counseling is delivered in the future and may help clinics spend more time on individualized questions instead of repeating generic information.

Waitlist Available
Has No Placebo

Byers Eye Institute

Robert T Chang, MD

Image of University of New Brunswick in Fredericton, Canada.

Mediterranean Diet for Toddler Health

24 - 36
All Sexes
Fredericton, Canada

Toddlerhood (ages 2-3) is a critical window when the gut microbiome is still developing and eating habits are being established. Yet, many Canadian toddlers eat diets high in sugar and salt, which may affect long-term health. This study will test whether a MED diet can improve dietary inflammation, gut health, and body composition in toddlers and whether a tailored nutrition education program for parents can help families maintain healthy eating patterns. In this study, toddlers will be randomly assigned to a 3-week MED diet or their usual diet. Families in the MED diet group will receive free meal boxes for the 3 weeks, plus guidance from a nutrition researcher through a structured education program. The standard diet group will continue their regular diet with general nutrition advice. Researchers will collect dietary information, body composition assessments, and stool samples to measure gut microbiome composition and metabolites. This first study of a controlled diet intervention in toddlers, combining behavioral support, high-quality food provision, and advanced gut microbiome analysis, will help understand how early diet shapes lifelong eating habits and health, guiding public health strategies and precision nutrition approaches to prevent chronic disease from early life.

Waitlist Available
Has No Placebo

University of New Brunswick

Dr. Maryam Kebbe, PhD, CLC

Have you considered Diclofenac Sodium And Misoprostol clinical trials?

We made a collection of clinical trials featuring Diclofenac Sodium And Misoprostol, we think they might fit your search criteria.
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Have you considered Diclofenac Sodium And Misoprostol clinical trials?

We made a collection of clinical trials featuring Diclofenac Sodium And Misoprostol, we think they might fit your search criteria.
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