Diabinese

Type 2 Diabetes, Diabetes Insipidus
Treatment
1 FDA approval
20 Active Studies for Diabinese

What is Diabinese

ChlorpropamideThe Generic name of this drug
Treatment SummaryChlorpropamide is a type of medication used to treat non-insulin dependent diabetes (NIDDM). It works by stimulating the pancreas to produce insulin, which helps control blood sugar levels. This type of medication has the potential to cause weight gain and hypoglycemia, especially in elderly, debilitated and malnourished people. Chlorpropamide is not recommended for treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33). It is mainly metabolized in the liver and then excreted in the urine, but this process may be affected
Diabineseis the brand name
Diabinese Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Diabinese
Chlorpropamide
1958
9

Approved as Treatment by the FDA

Chlorpropamide, otherwise called Diabinese, is approved by the FDA for 1 uses including Type 2 Diabetes .
Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus

Effectiveness

How Diabinese Affects PatientsChlorpropamide is a type of medication used to treat type II diabetes. It helps to reduce blood sugar levels when taken with diet and exercise. Chlorpropamide is twice as powerful as a similar diabetes medication called glipizide.
How Diabinese works in the bodyChlorpropamide helps the pancreas produce insulin by blocking potassium channels on the cells. This causes the cells to become charged and increase the amount of calcium ions inside them. The increased calcium ions cause the pancreas to release insulin.

When to interrupt dosage

The beneficial dosage of Diabinese is contingent upon the diagnosed state. The amount also diverges according to the technique of delivery as indicated in the table below.
Condition
Dosage
Administration
Type 2 Diabetes
100.0 mg, , 250.0 mg
Tablet - Oral, , Oral, Tablet
Diabetes Insipidus
100.0 mg, , 250.0 mg
Tablet - Oral, , Oral, Tablet

Warnings

Diabinese has two counter-indications. It ought not to be taken when suffering from any of the conditions listed in the following table.Diabinese Contraindications
Condition
Risk Level
Notes
Diabetic Ketoacidosis
Do Not Combine
Type 1 Diabetes
Do Not Combine
There are 20 known major drug interactions with Diabinese.
Common Diabinese Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Minor
Chlorpropamide may increase the anticoagulant activities of (R)-warfarin.
(S)-Warfarin
Minor
Chlorpropamide may increase the anticoagulant activities of (S)-Warfarin.
Abacavir
Minor
Chlorpropamide may decrease the excretion rate of Abacavir which could result in a higher serum level.
Abrocitinib
Minor
The metabolism of Abrocitinib can be decreased when combined with Chlorpropamide.
Aclidinium
Minor
Chlorpropamide may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Diabinese Toxicity & Overdose RiskThe lowest toxic dose of IPN-RAT has been found to be 580mg/kg.
image of a doctor in a lab doing drug, clinical research

Diabinese Novel Uses: Which Conditions Have a Clinical Trial Featuring Diabinese?

164 active trials are presently investigating the potential of Diabinese in the management of Diabetes Insipidus.
Condition
Clinical Trials
Trial Phases
Diabetes Insipidus
2 Actively Recruiting
Phase 1, Phase 2
Type 2 Diabetes
176 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Early Phase 1, Phase 1, Phase 3

Diabinese Reviews: What are patients saying about Diabinese?

5Patient Review
1/31/2012
Diabinese for Type 2 Diabetes Mellitus
I didn't experience any negative side effects with this treatment, which was great since that's not something I can say about other similar medications like metforman and glyberide.
4.3Patient Review
9/24/2007
Diabinese for Type 2 Diabetes Mellitus
I've been a NIDD since '79 and Diabinese has really helped me keep things under control. I have to go for glucose checks pretty frequently, but it's worth it to stay healthy.

Patient Q&A Section about diabinese

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the action of chlorpropamide?

"This medication helps lower blood sugar by causing the pancreas to produce insulin, which is a natural substance needed to break down sugar in the body, and by helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally."

Answered by AI

Is Diabinese available?

"The prescription drug Diabinese is not currently available in the United States in a form that is therapeutically equivalent to the brand-name version. It is important to note that there may be illegal generic versions of Diabinese being sold by fraudulent online pharmacies."

Answered by AI

What drug class is Diabinese?

"Diabinese is

used to help control blood sugar in people with type 2 diabetes.

Diabinese is a drug that helps control blood sugar in people with type 2 diabetes. It belongs

to a class of drugs called antidiabetics or sulfonylureas."

Answered by AI

What is Diabinese used for?

"The diabetes medicine Diabinese (chlorpropamide) is taken orally. It is typically used with diet and exercise to treat type 2 diabetes, which is also known as non-insulin dependent diabetes. If necessary, other diabetes medicines can be used alongside Diabinese. The generic form of this medicine is also available."

Answered by AI

Clinical Trials for Diabinese

Have you considered Diabinese clinical trials? We made a collection of clinical trials featuring Diabinese, we think they might fit your search criteria.
Have you considered Diabinese clinical trials? We made a collection of clinical trials featuring Diabinese, we think they might fit your search criteria.
Have you considered Diabinese clinical trials? We made a collection of clinical trials featuring Diabinese, we think they might fit your search criteria.
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