Dayvigo

Insomnia

Treatment

1 Active Study for Dayvigo

Treatment for

Insomnia

What is Dayvigo

LemborexantThe Generic name of this drug

Treatment SummaryLemborexant is a drug used to treat insomnia. It is different from traditional sleep medications because it reduces inappropriate wakefulness instead of increasing the ability to fall asleep. It is believed to be more effective and have fewer side effects than other medications used to treat insomnia.

Dayvigois the brand name

image of different drug pills on a surface

Dayvigo Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Dayvigo

Lemborexant

2020

Effectiveness

How Dayvigo Affects PatientsLemborexant helps to bring on sleep by blocking wake-promoting chemicals in the brain. In some cases, people taking this drug have done things while asleep that they don't remember, like eating, having sex, or making phone calls. If this happens, the drug should be stopped right away. Lemborexant can also be addictive for people who have a history of alcohol and drug abuse, so it should be used with caution. The Drug Enforcement Administration is looking into how to classify this drug.

How Dayvigo works in the bodyLemborexant is a drug that helps with sleep by blocking the activity of two types of receptors in the hypothalamus. These receptors are normally activated by orexin-A and -B, which are molecules that help keep us awake. When lemborexant binds to these receptors, it prevents the orexin molecules from activating them and thus helps us sleep.

When to interrupt dosage

The quantity of Dayvigo is conditioned by the diagnosed disorder. The dosage is contingent upon the method of delivery (e.g. Tablet - Oral or Tablet, film coated - Oral) as illustrated in the table below.

Condition

Dosage

Administration

Insomnia

10.0 mg, , 5.0 mg

Tablet, film coated - Oral, Tablet, film coated, , Oral, Tablet, Tablet - Oral

Warnings

Dayvigo Contraindications

Condition

Risk Level

Notes

Narcolepsy

Do Not Combine

There are 20 known major drug interactions with Dayvigo.

Common Dayvigo Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Lemborexant.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Lemborexant.

Azelastine

Major

Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Lemborexant.

Copanlisib

Major

The metabolism of Copanlisib can be decreased when combined with Lemborexant.

Dayvigo Toxicity & Overdose RiskExperiences with overdosing on lemborexant are rare. In studies, people who took doses up to 10 times the recommended amount experienced more side effects like sleepiness. If someone overdoses on lemborexant, supportive measures should be taken and medical assistance should be sought. Since lemborexant binds to proteins, dialysis is not likely to be helpful in an overdose situation.

image of a doctor in a lab doing drug, clinical research

Dayvigo Novel Uses: Which Conditions Have a Clinical Trial Featuring Dayvigo?

82 active studies are investigating the potential of Dayvigo to mitigate Insomnia symptoms.

Condition

Clinical Trials

Trial Phases

Insomnia

1 Actively Recruiting

Not Applicable