Your session is about to expire
What is Dayvigo
LemborexantThe Generic name of this drug
Treatment SummaryLemborexant is a drug used to treat insomnia. It is different from traditional sleep medications because it reduces inappropriate wakefulness instead of increasing the ability to fall asleep. It is believed to be more effective and have fewer side effects than other medications used to treat insomnia.
Dayvigois the brand name
Dayvigo Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dayvigo
Lemborexant
2020
3
Effectiveness
How Dayvigo Affects PatientsLemborexant helps to bring on sleep by blocking wake-promoting chemicals in the brain. In some cases, people taking this drug have done things while asleep that they don't remember, like eating, having sex, or making phone calls. If this happens, the drug should be stopped right away. Lemborexant can also be addictive for people who have a history of alcohol and drug abuse, so it should be used with caution. The Drug Enforcement Administration is looking into how to classify this drug.
How Dayvigo works in the bodyLemborexant is a drug that helps with sleep by blocking the activity of two types of receptors in the hypothalamus. These receptors are normally activated by orexin-A and -B, which are molecules that help keep us awake. When lemborexant binds to these receptors, it prevents the orexin molecules from activating them and thus helps us sleep.
When to interrupt dosage
The quantity of Dayvigo is conditioned by the diagnosed disorder. The dosage is contingent upon the method of delivery (e.g. Tablet - Oral or Tablet, film coated - Oral) as illustrated in the table below.Condition
Dosage
Administration
Insomnia
10.0 mg, , 5.0 mg
Tablet, film coated - Oral, Tablet, film coated, , Oral, Tablet, Tablet - Oral
Warnings
Dayvigo ContraindicationsCondition
Risk Level
Notes
Narcolepsy
Do Not Combine
Common Dayvigo Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Lemborexant.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Lemborexant.
Azelastine
Major
Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Lemborexant.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Lemborexant.
Dayvigo Toxicity & Overdose RiskExperiences with overdosing on lemborexant are rare. In studies, people who took doses up to 10 times the recommended amount experienced more side effects like sleepiness. If someone overdoses on lemborexant, supportive measures should be taken and medical assistance should be sought. Since lemborexant binds to proteins, dialysis is not likely to be helpful in an overdose situation.
Dayvigo Novel Uses: Which Conditions Have a Clinical Trial Featuring Dayvigo?
82 active studies are investigating the potential of Dayvigo to mitigate Insomnia symptoms.Condition
Clinical Trials
Trial Phases
Insomnia
93 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1
Dayvigo Reviews: What are patients saying about Dayvigo?
5Patient Review
3/12/2022 The pill works quickly, usually within 15-30 minutes. I find that it's easy to resist at first but eventually it will make you sleepy. It's an excellent sleep aid with no side effects that I can tell, other than maybe some brain fog or zoned out feeling during the day.
4Patient Review
7/26/2022 I've been taking Vigo for seven months. After the first month, I started seeing results which lasted for six months. Now it seems like the effectiveness is wearing off, so I'm hoping to get it under control again.
4Patient Review
9/4/2022 This medication was effective in helping me both fall and stay asleep, without making me feel groggy or drowsy the next day.
3Patient Review
8/26/2021 I've been using Ambien for over a decade, but my rheumatologist suggested I give Dayvigo a try. He gave me a sample package and recommended starting with the 5 mg dose and increasing to 10 if necessary. The first night was not good; I couldn't fall asleep or stay asleep. The second night was slightly better (I slept for about 6 hours), but it didn't help me get to sleep.
2.3Patient Review
3/25/2021 Dayvigo was prescribed to me for insomnia that I'd been experiencing for about three weeks. The first night, it did help me fall asleep around 9 PM. However, I woke up at 11:30 PM and could not get back to sleep. So while it may be helpful in getting you to sleep initially, it does not keep you asleep throughout the night. Additionally, there are no side effects that I experienced.
2Patient Review
6/30/2022 I didn't find this treatment helpful at all. I still only slept for four hours each night.
1.7Patient Review
4/5/2022 I have had issues with insomnia since childhood and I've tried a lot of different medications to help. Unfortunately, they all stopped working eventually. Dayvigo was the latest one I tried, and it made me sick within half an hour. Definitely not recommended.
1.7Patient Review
7/28/2022 I found that this medication didn't actually help me sleep, despite making me feel incredibly tired. I just lay in bed for hours with racing thoughts, which is honestly worse than not being able to sleep at all. There are other medications out there that work much better for insomnia; don't bother with this one.
1Patient Review
3/5/2022 DayVigo was an absolutely terrible experience for me. I felt like my heart was racing, and all my body sensations were wrong. It was easily the worst night of my life.
1Patient Review
2/28/2021 The side effects of this medication were too much for me to handle after only two nights. I experienced manic/panic attacks in the middle of the night, which caused headaches, blurred vision, shaking, and an overall feeling of unease. The nurse line advised me to stop taking the medication, and I would say that's good advice for anyone else considering it.
1Patient Review
6/17/2020 Even after taking this for over a week, I haven't seen any improvement in my sleep patterns. If anything, the headaches I've been experiencing might be related to the medication.
1Patient Review
7/20/2022 I would not recommend this drug as it gave me nightmares the whole night.
1Patient Review
9/12/2022 I had a really bad experience every time I used this drug. Sleep paralysis and horrible hallucinations/ nightmares. The next day I would be really foggyheaded.
Patient Q&A Section about dayvigo
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Dayvigo a controlled substance?
"DAYVIGO is a federally controlled substance because it can be abused or cause dependence. Keep DAYVIGO in a safe place to prevent misuse and abuse. Selling or giving away DAYVIGO may harm others and is against the law."
Answered by AI
How long does it take for Dayvigo to start working?
"Dayvigo works best if it is taken at bedtime. If your insomnia does not improve after taking Dayvigo for 7-10 days, you should talk to your doctor to see if there are any other medical conditions that could be causing your insomnia."
Answered by AI
Is Dayvigo the same as Ambien?
"Dayvigo is an orexin receptor antagonist.
The two drugs used to treat insomnia, Dayvigo and Ambien, work in different ways. Ambien is a sedative/hypnotic, while Dayvigo is an orexin receptor antagonist."
Answered by AI
Is Dayvigo a good sleeping pill?
"Dayvigo works by blocking orexin receptors in the brain. Orexin receptors are usually responsive to orexin neurotransmitters, which are important for regulating the sleep-wake cycle. Blocking these receptors with Dayvigo can improve sleep at night."
Answered by AI