Dayvigo

Insomnia

Treatment

0 Active Studies for Dayvigo

What is Dayvigo

Lemborexant

The Generic name of this drug

Treatment Summary

Lemborexant is a drug used to treat insomnia. It is different from traditional sleep medications because it reduces inappropriate wakefulness instead of increasing the ability to fall asleep. It is believed to be more effective and have fewer side effects than other medications used to treat insomnia.

Dayvigo

is the brand name

image of different drug pills on a surface

Dayvigo Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Dayvigo

Lemborexant

2020

3

Effectiveness

How Dayvigo Affects Patients

Lemborexant helps to bring on sleep by blocking wake-promoting chemicals in the brain. In some cases, people taking this drug have done things while asleep that they don't remember, like eating, having sex, or making phone calls. If this happens, the drug should be stopped right away. Lemborexant can also be addictive for people who have a history of alcohol and drug abuse, so it should be used with caution. The Drug Enforcement Administration is looking into how to classify this drug.

How Dayvigo works in the body

Lemborexant is a drug that helps with sleep by blocking the activity of two types of receptors in the hypothalamus. These receptors are normally activated by orexin-A and -B, which are molecules that help keep us awake. When lemborexant binds to these receptors, it prevents the orexin molecules from activating them and thus helps us sleep.

When to interrupt dosage

The quantity of Dayvigo is conditioned by the diagnosed disorder. The dosage is contingent upon the method of delivery (e.g. Tablet - Oral or Tablet, film coated - Oral) as illustrated in the table below.

Condition

Dosage

Administration

Insomnia

10.0 mg, , 5.0 mg

Tablet, film coated, Oral, , Tablet, film coated - Oral, Tablet, Tablet - Oral

Warnings

Dayvigo Contraindications

Condition

Risk Level

Notes

Narcolepsy

Do Not Combine

There are 20 known major drug interactions with Dayvigo.

Common Dayvigo Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Lemborexant.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Lemborexant.

Azelastine

Major

Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Lemborexant.

Copanlisib

Major

The metabolism of Copanlisib can be decreased when combined with Lemborexant.

Dayvigo Toxicity & Overdose Risk

Experiences with overdosing on lemborexant are rare. In studies, people who took doses up to 10 times the recommended amount experienced more side effects like sleepiness. If someone overdoses on lemborexant, supportive measures should be taken and medical assistance should be sought. Since lemborexant binds to proteins, dialysis is not likely to be helpful in an overdose situation.

image of a doctor in a lab doing drug, clinical research

Dayvigo Novel Uses: Which Conditions Have a Clinical Trial Featuring Dayvigo?

82 active studies are investigating the potential of Dayvigo to mitigate Insomnia symptoms.

Condition

Clinical Trials

Trial Phases

Insomnia

0 Actively Recruiting

Dayvigo Reviews: What are patients saying about Dayvigo?

5

Patient Review

3/12/2022

Dayvigo for Chronic Trouble Sleeping

The pill works quickly, usually within 15-30 minutes. I find that it's easy to resist at first but eventually it will make you sleepy. It's an excellent sleep aid with no side effects that I can tell, other than maybe some brain fog or zoned out feeling during the day.

4

Patient Review

7/26/2022

Dayvigo for Chronic Trouble Sleeping

I've been taking Vigo for seven months. After the first month, I started seeing results which lasted for six months. Now it seems like the effectiveness is wearing off, so I'm hoping to get it under control again.

4

Patient Review

9/4/2022

Dayvigo for Chronic Trouble Sleeping

This medication was effective in helping me both fall and stay asleep, without making me feel groggy or drowsy the next day.

3

Patient Review

8/26/2021

Dayvigo for Chronic Trouble Sleeping

I've been using Ambien for over a decade, but my rheumatologist suggested I give Dayvigo a try. He gave me a sample package and recommended starting with the 5 mg dose and increasing to 10 if necessary. The first night was not good; I couldn't fall asleep or stay asleep. The second night was slightly better (I slept for about 6 hours), but it didn't help me get to sleep.

2.3

Patient Review

3/25/2021

Dayvigo for Chronic Trouble Sleeping

Dayvigo was prescribed to me for insomnia that I'd been experiencing for about three weeks. The first night, it did help me fall asleep around 9 PM. However, I woke up at 11:30 PM and could not get back to sleep. So while it may be helpful in getting you to sleep initially, it does not keep you asleep throughout the night. Additionally, there are no side effects that I experienced.

2

Patient Review

6/30/2022

Dayvigo for Chronic Trouble Sleeping

I didn't find this treatment helpful at all. I still only slept for four hours each night.

1.7

Patient Review

4/5/2022

Dayvigo for Chronic Trouble Sleeping

I have had issues with insomnia since childhood and I've tried a lot of different medications to help. Unfortunately, they all stopped working eventually. Dayvigo was the latest one I tried, and it made me sick within half an hour. Definitely not recommended.

1.7

Patient Review

7/28/2022

Dayvigo for Chronic Trouble Sleeping

I found that this medication didn't actually help me sleep, despite making me feel incredibly tired. I just lay in bed for hours with racing thoughts, which is honestly worse than not being able to sleep at all. There are other medications out there that work much better for insomnia; don't bother with this one.

1

Patient Review

3/5/2022

Dayvigo for Chronic Trouble Sleeping

DayVigo was an absolutely terrible experience for me. I felt like my heart was racing, and all my body sensations were wrong. It was easily the worst night of my life.

1

Patient Review

2/28/2021

Dayvigo for Chronic Trouble Sleeping

The side effects of this medication were too much for me to handle after only two nights. I experienced manic/panic attacks in the middle of the night, which caused headaches, blurred vision, shaking, and an overall feeling of unease. The nurse line advised me to stop taking the medication, and I would say that's good advice for anyone else considering it.

1

Patient Review

6/17/2020

Dayvigo for Chronic Trouble Sleeping

Even after taking this for over a week, I haven't seen any improvement in my sleep patterns. If anything, the headaches I've been experiencing might be related to the medication.

1

Patient Review

7/20/2022

Dayvigo for Chronic Trouble Sleeping

I would not recommend this drug as it gave me nightmares the whole night.

1

Patient Review

9/12/2022

Dayvigo for Chronic Trouble Sleeping

I had a really bad experience every time I used this drug. Sleep paralysis and horrible hallucinations/ nightmares. The next day I would be really foggyheaded.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about dayvigo

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Dayvigo a controlled substance?

"DAYVIGO is a federally controlled substance because it can be abused or cause dependence. Keep DAYVIGO in a safe place to prevent misuse and abuse. Selling or giving away DAYVIGO may harm others and is against the law."

Answered by AI

How long does it take for Dayvigo to start working?

"Dayvigo works best if it is taken at bedtime. If your insomnia does not improve after taking Dayvigo for 7-10 days, you should talk to your doctor to see if there are any other medical conditions that could be causing your insomnia."

Answered by AI

Is Dayvigo the same as Ambien?

"Dayvigo is an orexin receptor antagonist.

The two drugs used to treat insomnia, Dayvigo and Ambien, work in different ways. Ambien is a sedative/hypnotic, while Dayvigo is an orexin receptor antagonist."

Answered by AI

Is Dayvigo a good sleeping pill?

"Dayvigo works by blocking orexin receptors in the brain. Orexin receptors are usually responsive to orexin neurotransmitters, which are important for regulating the sleep-wake cycle. Blocking these receptors with Dayvigo can improve sleep at night."

Answered by AI