Cortifoam

Scleritis, Iridocyclitis, Iritis + 47 more

Treatment

22 FDA approvals

20 Active Studies for Cortifoam

What is Cortifoam

Hydrocortisone acetate

The Generic name of this drug

Cortisporin

is the brand name

Cortifoam Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cortisporin

Hydrocortisone acetate

1963

43

Approved as Treatment by the FDA

Hydrocortisone acetate, commonly known as Cortisporin, is approved by the FDA for 22 uses which include Hypersensitivity and Neoplastic Disease .

Hypersensitivity

Neoplastic Disease

Collagen Diseases

Rheumatoid Arthritis

Helps manage Rheumatoid Arthritis

Skin Diseases

Androgenital syndrome

Helps manage Androgenital syndrome

Haemorrhoids

Thyroiditis

Helps manage Thyroiditis

Thyroiditis

Helps manage Thyroiditis

Dermatological Disease

Itching

Ulcerative Colitis

Used in combination with other therapies

Pruritus

hormonal disorder

Proctitis

Helps manage Proctitis

Atopic Dermatitis

Skin Irritation

Adrenal Insufficiency

Helps manage Adrenal cortical hypofunctions

Ulcerative Colitis

Used in combination with other therapies

Adrenal cortical hypofunctions

Helps manage Adrenal cortical hypofunctions

Proctitis

Helps manage Proctitis

cryptitis

Helps manage cryptitis

Effectiveness

How Cortifoam Affects Patients

Hydrocortisone is a steroid hormone that helps the body with important functions like controlling blood pressure, managing metabolism, and regulating the immune system. It comes in topical form and is used to reduce inflammation caused by certain skin disorders. Glucocorticoids, like hydrocortisone, stop certain cytokines (IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8 and TNF-alpha) from being produced, which decreases the number of T cells that can be activated. It also reduces the amount of IL-2 and IL-2

How Cortifoam works in the body

Hydrocortisone works by attaching to the glucocorticoid receptor in cells. This receptor then travels to the cell nucleus and binds to special response elements in the DNA. This helps increase the expression of specific genes that help reduce inflammation. The anti-inflammatory effects of hydrocortisone are also thought to be a result of it reducing the production of prostaglandins and leukotrienes, which are both involved in inflammation. Hydrocortisone also works by preventing certain inflammatory processes from occurring, such as epithelial adhesion, emigration, chemotaxis, and phagocytosis.

When to interrupt dosage

The amount of Cortifoam is contingent upon the recognized condition, including Pink Eye, Skin Infections and hormonal disorder. The measure shifts as per the procedure of delivery delineated in the table beneath.

Condition

Dosage

Administration

Acute, Inflammatory Superficial Cutaneous Lesions caused by susceptible bacteria

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Thyroiditis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Itching

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Blepharitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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ocular bacterial infections

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Adrenal Insufficiency

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Communicable Diseases

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Adrenal Cortex Hormones

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Collagen Diseases

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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hormonal disorder

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Ulcerative Colitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Anorectal Surgeries

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Fissure in Ano

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Anal inflammation

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Proctitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Postoperative

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Allergic Conjunctivitis (AC)

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Dermatitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Hemorrhoids

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

Topical, , Aerosol, foam, Aerosol, foam - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Ointment, Ointment - Topical, Kit, Suppository - Rectal, Rectal, Suppository, Cream - Rectal, Gel - Rectal, Gel, Gel - Topical, Aerosol, foam - Rectal, Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Suspension - Auricular (otic); Ophthalmic, Suspension, Rectal; Topical, Ointment - Rectal; Topical, Ointment - Rectal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Aerosol, Aerosol - Rectal, Soap, Soap - Topical, Powder - Topical, Powder, for solution - Topical, Powder, for solution, Powder, Cream - Rectal; Topical, Lotion / shampoo, Lotion / shampoo - Topical, Ointment - Ophthalmic, Shampoo - Topical, Shampoo, Kit - Topical, Solution, Solution - Topical, Auricular (otic), Solution / drops - Auricular (otic), Suspension - Ophthalmic, Suspension - Auricular (otic), Kit - Oral, Oral, Kit - Irrigation; Ophthalmic; Topical, Irrigation; Ophthalmic; Topical, Kit - Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Oral; Rectal, Kit - Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Topical, Kit - Respiratory (inhalation); Topical, Kit - Ophthalmic; Topical, Ophthalmic; Respiratory (inhalation); Topical, Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Respiratory (inhalation); Topical

Androgenital syndrome

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

Topical, , Aerosol, foam, Aerosol, foam - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Ointment, Ointment - Topical, Kit, Suppository - Rectal, Rectal, Suppository, Cream - Rectal, Gel - Rectal, Gel, Gel - Topical, Aerosol, foam - Rectal, Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Suspension - Auricular (otic); Ophthalmic, Suspension, Rectal; Topical, Ointment - Rectal; Topical, Ointment - Rectal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Aerosol, Aerosol - Rectal, Soap, Soap - Topical, Powder - Topical, Powder, for solution - Topical, Powder, for solution, Powder, Cream - Rectal; Topical, Lotion / shampoo, Lotion / shampoo - Topical, Ointment - Ophthalmic, Shampoo - Topical, Shampoo, Kit - Topical, Solution, Solution - Topical, Auricular (otic), Solution / drops - Auricular (otic), Suspension - Ophthalmic, Suspension - Auricular (otic), Kit - Oral, Oral, Kit - Irrigation; Ophthalmic; Topical, Irrigation; Ophthalmic; Topical, Kit - Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Oral; Rectal, Kit - Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Topical, Kit - Respiratory (inhalation); Topical, Kit - Ophthalmic; Topical, Ophthalmic; Respiratory (inhalation); Topical, Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Respiratory (inhalation); Topical

Warnings

There are 20 known major drug interactions with Cortifoam.

Common Cortifoam Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Hydrocortisone acetate.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Hydrocortisone acetate.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Hydrocortisone acetate.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Hydrocortisone acetate.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Hydrocortisone acetate.

Cortifoam Toxicity & Overdose Risk

Taking too much of this drug may inhibit bone growth, reduce calcium absorption in the body, and slow the healing of wounds.

image of a doctor in a lab doing drug, clinical research

Cortifoam Novel Uses: Which Conditions Have a Clinical Trial Featuring Cortifoam?

91 active investigations are assessing the potential of Cortifoam to provide relief from cryptitis, Ocular disorders, and Dermatitis.

Condition

Clinical Trials

Trial Phases

Rheumatoid Arthritis

55 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Open-angle glaucoma

45 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4, Early Phase 1, Phase 1

Thyroiditis

0 Actively Recruiting

Adrenal Insufficiency

0 Actively Recruiting

Fluorophotometry

0 Actively Recruiting

Eczema

0 Actively Recruiting

Ulcerative Colitis

14 Actively Recruiting

Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1

Anorectal Surgeries

0 Actively Recruiting

Defecation

0 Actively Recruiting

Iritis

0 Actively Recruiting

Proctitis

0 Actively Recruiting

Hypersensitivity

1 Actively Recruiting

Phase 4

Allergic Conjunctivitis (AC)

1 Actively Recruiting

Phase 2

Dermatologic disorders

0 Actively Recruiting

Scleritis

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Androgenital syndrome

0 Actively Recruiting

Haemorrhoids

1 Actively Recruiting

Not Applicable

Neoplastic Disease

1 Actively Recruiting

Phase 1

Dermatitis

1 Actively Recruiting

Not Applicable

Cortifoam Reviews: What are patients saying about Cortifoam?

3.3

Patient Review

11/28/2007

Cortifoam for Ulceration of the Rectum

This medication does the job, but I still experience pain during bowel movements that can last up to 20 minutes.

1.3

Patient Review

3/25/2013

Cortifoam for Ulceration of the Rectum

Not good.

1

Patient Review

5/30/2016

Cortifoam for Ulceration of the Rectum

I agree with the previous complaint—the applicator doesn't work properly. You either can't get the medication out, or there's not enough in it. Not happy about this purchase.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cortifoam

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Cortifoam used for?

"This medication is used to treat a certain intestinal problem known as ulcerative colitis of the rectum. It may relieve rectal pain, diarrhea, and bloody stools caused by swelling (inflammation), but it does not cure this condition."

Answered by AI

How many doses are in Cortifoam?

"Cortifoam is supplied in a container that can be sprayed with a special applicator designed for the rectum. Each applicator contains 900 mg of foam, with 80 mg of hydrocortisone. The container should provide a minimum of 14 applications."

Answered by AI

Is Cortifoam a steroid?

"Cortifoam is a retail steroid foam that contains hydrocortisone. It is used to treat symptoms of ulcerative proctitis, which is inflammation or swelling of the lower intestine."

Answered by AI

Is Cortifoam available?

"There is no equivalent of Cortifoam currently available in the United States. However, some online pharmacies may sell counterfeit or dangerous versions of the drug."

Answered by AI

Clinical Trials for Cortifoam

Image of Indiana Universtiy School of Optometry in Bloomington, United States.

Netarsudil for Glaucoma and Ocular Hypertension

18+
All Sexes
Bloomington, IN

This study evaluates the effects of netarsudil (Rhopressa) on the trabecular meshwork in subjects with ocular hypertension or open-angle glaucoma. Participants will be randomized to receive either netarsudil or placebo (artificial tears). High-resolution imaging using adaptive optics gonioscopy, anterior segment optical coherence tomography (AS-OCT), and OCT gonioscopy will be performed at baseline and after approximately 14 days of treatment. The primary objective is to assess changes in trabecular meshwork lamellae spacing, with secondary measures including trabecular meshwork height, width, and Schlemm's canal diameter.

Phase 4
Waitlist Available

Indiana Universtiy School of Optometry

Alcon Research

Image of University of Oklahoma Health Campus in Oklahoma City, United States.

Disulfiram for Rheumatoid Arthritis

18 - 75
All Sexes
Oklahoma City, OK

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent joint inflammation and systemic immune activation. Obesity is common among individuals with RA and is associated with increased disease activity, reduced treatment response, and worse functional outcomes. Inflammation in adipose tissue, driven in part by activation of the NLRP3 inflammasome and downstream gasdermin D (GSDMD)-mediated pathways, may contribute to systemic inflammation and RA disease severity. Disulfiram (DSF), an FDA-approved medication for alcohol use disorder, has recently been identified as an inhibitor of GSDMD-mediated inflammatory signaling and pyroptosis. Preclinical studies suggest that DSF reduces inflammasome activation, inflammatory cytokine release, and metabolic dysfunction. This study is a 12-week, randomized, double-blind, placebo-controlled pilot trial designed to evaluate the safety, tolerability, and preliminary efficacy of DSF in overweight and obese adults with active RA despite stable disease-modifying antirheumatic drug (DMARD) therapy. Participants will be randomized to receive either DSF (250 mg daily) or placebo. The primary objective is to assess safety and tolerability. Secondary and exploratory objectives include evaluating the effects of DSF on systemic inflammation, RA disease activity, metabolic parameters, and adipose tissue inflammasome activation. Findings from this study will inform the feasibility and design of larger clinical trials targeting GSDMD-mediated inflammation in RA.

Phase 2
Waitlist Available

University of Oklahoma Health Campus

Beatriz Y Hanaoka, MD, MSc

Image of Hopital general de Montreal in Montreal, Canada.

Nurse-led Telehealth for Rheumatoid Arthritis

18+
All Sexes
Montreal, Canada

Canada urgently needs new ways to provide rheumatology care that improve treatment and make it easier for people to get high-quality care. E-health technology is a new and promising way to do this, but it hasn't been studied much yet in rheumatology. The investigators will test a new way to help people with rheumatoid arthritis at four clinics in Quebec. This study will check if the new approach is easy to use, fits well into the clinics' daily routine, and if both patients and healthcare workers find it helpful and acceptable. This new approach involves nurses helping patients check their own health from home using an online platform. 104 adults who have rheumatoid arthritis and who have had a flare-up or a change in their medication in the last three months, will participate. Some will start using the online self-monitoring tool right away for 16 months, while others will continue with their usual care for 8 months before trying the tool. During the time they use the tool, they will fill out monthly online questionnaires to check their health. A rheumatology nurse will review their answers, suggest any needed care, provide personalized health information, and be available to answer questions through messages. This new way of care, where nurses help patients monitor their rheumatoid arthritis from home, helps make better use of limited specialist time. It's more convenient for patients, especially those who live far away, and helps meet their needs between regular doctor visits while keeping the quality of care high.

Waitlist Available
Has No Placebo

Hopital general de Montreal (+3 Sites)

Laetitia Michou, MD PhD

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Image of Resilient Roots: Functional Medicine in Charlottesville, United States.

Ketogenic and Carnivore Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

18 - 64
All Sexes
Charlottesville, VA

This study is a randomized controlled clinical trial evaluating whether two therapeutic dietary approaches - a ketogenic diet and a carnivore (lion) diet - can improve quality of life, reduce symptoms, and influence measures of disease activity in adults with inflammatory bowel disease \[ulcerative colitis and Crohn's disease\] (IBD) or rheumatoid arthritis (RA). Participants will be randomized into one of three groups: 1) Ketogenic Diet, 2) Carnivore (Lion) Diet or 3) Wait-List Control. Participants randomized to a dietary group (ketogenic diet or carnivore diet) will be provided guidance on their specific dietary therapy and answer questions about their symptoms and quality of life at different intervals over a 24 week period. Participants will also complete laboratory testing at different intervals to assess for changes in nutritional status, cardiometabolic health and markers of immune activation and inflammation. Participants initially placed on the wait-list group will be asked similar questions about their symptoms and quality of life and complete the same laboratory testing as participants in a dietary group. Participants on the wait list will then be compared to participants following a specific dietary pattern to assess for any differences between the 2 groups. After 12 weeks, participants on the wait list will be randomized to a dietary group (ketogenic diet or carnivore diet) and followed in a similar fashion for an additional 12 week period.

Recruiting
Has No Placebo

Resilient Roots: Functional Medicine

Robert D Abbott, MD

Image of UCSF Medical Center in San Francisco, United States.

Upadacitinib for Ulcerative Colitis

18 - 75
All Sexes
San Francisco, CA

The goal of this clinical trial is to learn if the oral medication upadacitinib can safely and effectively treat acute severe ulcerative colitis (ASUC) in adults who are hospitalized. It will also evaluate whether upadacitinib can be used without corticosteroids during initial treatment. The main questions it aims to answer are: 1. Does upadacitinib reduce treatment failure by Day 14 (defined as need for colectomy or rescue therapy)? 2. What side effects and safety events occur when using upadacitinib in hospitalized patients with ASUC? Researchers will compare outcomes in participants receiving upadacitinib to a historical group of similar patients previously treated with standard therapies, including intravenous corticosteroids and infliximab, to determine if upadacitinib improves outcomes. Participants will: 1. Take oral upadacitinib once daily during hospitalization. 2. Undergo routine clinical monitoring, including blood tests and symptom assessments. 3. Be followed after discharge with clinic visits or phone calls for up to 12 months to assess outcomes such as need for additional treatment, surgery, and safety events

Phase 4
Waitlist Available

UCSF Medical Center

Sara Lewin, MD

AbbVie

Image of Eye Centers of Southeast Texas in Beaumont, United States.

Rocklatan for Glaucoma

18+
All Sexes
Beaumont, TX

This is a randomized, double-masked, single-site, prospective, contralateral eye study designed to evaluate the outcomes of Direct Selective Laser Trabeculoplasty (DSLT) followed by the addition of combination netarsudil and latanoprost (Rocklatan) versus latanoprost monotherapy. The study will be conducted at one investigational site. The primary endpoint is the change in mean diurnal intraocular pressure (IOP) from baseline (post DSLT and post washout) at visit 3 between the two groups. Secondary endpoints include the change in mean IOP from baseline at each timepoint (8am, 12pm, 4pm) at visit 3 between groups, and the mean percentage decrease in IOP from baseline for each group. Assessments will be conducted at three key visits: Visit 1 (Screening Phase and DSLT Procedure on Day 0), Visit 2 (Baseline Visit post washout at Week 8), and Visit 3 (Follow-Up Visit 1 at Week 12). Each visit will include specific examinations and measurements such as visual field and OCT imaging, diurnal IOP measurements, and documentation of adverse events.

Phase 4
Waitlist Available

Eye Centers of Southeast Texas

Kevin Talbot, MD

Sengi

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Image of University Health Network/ Toronto Western Hospital in Toronto, Canada.

Biofeedback Training for Glaucoma

Any Age
All Sexes
Toronto, Canada

This randomized controlled clinical trial evaluates the efficacy of visual biofeedback training on visual function and quality of life in individuals with glaucoma. Glaucoma is a progressive optic neuropathy that can lead to irreversible vision loss, including impaired fixation stability, reduced retinal sensitivity, and decreased functional vision. Biofeedback training is a visual rehabilitation technique designed to help patients improve fixation stability and optimize use of remaining visual function by training eye movements toward retinal areas with better sensitivity. Seventy participants with glaucoma will be randomized to either a biofeedback training intervention group or a control group. Visual function outcomes, including fixation stability, retinal sensitivity, visual acuity, reading speed, contrast sensitivity, and quality of life, will be assessed at baseline and follow-up visits. This study aims to determine whether biofeedback training can improve visual function and quality of life in patients with glaucoma.

Recruiting
Has No Placebo

University Health Network/ Toronto Western Hospital

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