Cefdinir

Moraxella catarrhalis, Tonsillitis, Tonsillitis + 19 more

Treatment

22 FDA approvals

7 Active Studies for Cefdinir

What is Cefdinir

Cefdinir

The Generic name of this drug

Treatment Summary

Cefdinir, also known as Omnicef, is an antibiotic used to treat a wide range of bacterial infections in the ear, sinus, throat, lungs, and skin. It was approved by the FDA in 1997 and works by blocking the production of beta-lactamase enzymes which can make some bacteria resistant to first-line cephalosporin therapy. Cefdinir is a broad-spectrum antibiotic and is generally very effective and well-tolerated.

Omnicef

is the brand name

image of different drug pills on a surface

Cefdinir Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Omnicef

Cefdinir

1997

175

Approved as Treatment by the FDA

Cefdinir, also known as Omnicef, is approved by the FDA for 22 uses including Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza and Bronchitis .

Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza

Bronchitis

Maxillary Sinusitis

Tonsillitis

Bronchitis, Chronic

Haemophilus parainfluenzae

Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus

Acute exacerbation of chronic bronchitis caused by Haemophilus parainfluenzae

Haemophilus influenzae

Tonsillitis streptococcal

Haemophilus influenzae

Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae

Acute maxillary sinusitis caused by H. influenzae

Streptococcal Pharyngitis

acute otitis media caused by S.pneumoniae

Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae

Moraxella catarrhalis

Acute maxillary sinusitis caused by M. catarrhalis

Moraxella catarrhalis

Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae

Bronchitis

Moraxella catarrhalis

Effectiveness

How Cefdinir Affects Patients

Cefdinir is a drug used to treat bacterial infections by stopping the bacteria from creating new cell walls. It has a broad range of effectiveness against both gram-positive and gram-negative bacteria, and is even strong enough to fight against bacteria with beta-lactamase enzymes, which can make them resistant to other cephalosporins.

How Cefdinir works in the body

Cefdinir is an antibiotic with a stronger ability to kill bacteria than penicillin. It works by stopping the bacteria from building their cell walls, which eventually leads to their death. Cefdinir does this by binding to proteins in the bacteria's cell wall and blocking their ability to build the wall. It also has the added benefit of being able to resist enzymes that some bacteria produce to protect themselves from antibiotics. Cefdinir has been shown to target certain proteins in bacteria, but it is unclear how this contributes to its effectiveness.

When to interrupt dosage

The proposed dose of Cefdinir is hinged on the determined sickness, including Communicable Diseases, Bronchitis and Haemophilus parainfluenzae. The measure of dosage is contingent upon the management methodology (e.g. Capsule or Capsule - Oral) delineated in the accompanying table.

Condition

Dosage

Administration

Bronchitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Bronchitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Moraxella catarrhalis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Haemophilus influenzae

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Bronchitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Moraxella catarrhalis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Sinusitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Bronchitis, Chronic

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

acute otitis media caused by S.pneumoniae

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Communicable Diseases

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Maxillary Sinusitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Acute maxillary sinusitis caused by M. catarrhalis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Haemophilus parainfluenzae

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Haemophilus influenzae

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Tonsillitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Tonsillitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Streptococcal Pharyngitis

300.0 mg, , 125.0 mg/mL, 250.0 mg/mL

, Capsule, Oral, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Warnings

Cefdinir Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Cefdinir may interact with Pulse Frequency

There are 20 known major drug interactions with Cefdinir.

Common Cefdinir Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefdinir.

Abacavir

Minor

Cefdinir may decrease the excretion rate of Abacavir which could result in a higher serum level.

Abciximab

Minor

The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefdinir.

Aclidinium

Minor

Cefdinir may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Acrivastine

Minor

Cefdinir may decrease the excretion rate of Acrivastine which could result in a higher serum level.

Cefdinir Toxicity & Overdose Risk

The lowest toxic dose of cefdinir in rats is over 2000mg/kg. No side effects were reported from giving a single dose of 5600mg/kg to rodents. Symptoms of toxicity and overdose from other beta-lactam antibiotics include nausea, vomiting, diarrhea, abdominal pain, and seizures.

image of a doctor in a lab doing drug, clinical research

Cefdinir Novel Uses: Which Conditions Have a Clinical Trial Featuring Cefdinir?

Presently, there are 9 trials investigating the potential of Cefdinir to reduce Tonsillitis, Streptococcal Pharyngitis and Communicable Diseases.

Condition

Clinical Trials

Trial Phases

Streptococcal Pharyngitis

0 Actively Recruiting

Tonsillitis

2 Actively Recruiting

Not Applicable, Phase 4

Haemophilus influenzae

0 Actively Recruiting

Moraxella catarrhalis

0 Actively Recruiting

Haemophilus influenzae

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Bronchitis

0 Actively Recruiting

Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus

0 Actively Recruiting

Sinusitis

0 Actively Recruiting

Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae

0 Actively Recruiting

Maxillary Sinusitis

0 Actively Recruiting

Community Acquired Pneumonia (CAP)

5 Actively Recruiting

Not Applicable, Phase 1, Phase 3

Moraxella catarrhalis

0 Actively Recruiting

Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae

0 Actively Recruiting

Acute maxillary sinusitis caused by M. catarrhalis

0 Actively Recruiting

acute otitis media caused by S.pneumoniae

0 Actively Recruiting

Bronchitis

0 Actively Recruiting

Haemophilus parainfluenzae

0 Actively Recruiting

Moraxella catarrhalis

0 Actively Recruiting

Bronchitis, Chronic

0 Actively Recruiting

Cefdinir Reviews: What are patients saying about Cefdinir?

5

Patient Review

9/27/2022

Cefdinir for Bacterial Urinary Tract Infection

I took this medication on a full stomach with no problems whatsoever. I would definitely recommend it to others who might have a sensitive stomach.

5

Patient Review

10/18/2022

Cefdinir for Bacterial Urinary Tract Infection

Despite being a bit hesitant due to other reviews, I decided to give this medication a try for my recurrent UTI issue. Thankfully, it worked like a charm and I haven't had any issues since!

4

Patient Review

9/30/2022

Cefdinir for infection caused by bacteria

Though the taste of the pills was vile, this medication was very effective.

3.7

Patient Review

8/9/2021

Cefdinir for Acute Maxillary Sinus S. Pneumoniae Bacteria Infection

It's important to take probiotics and eat yogurt while you're taking this antibiotic, in order to stop a yeast infection from developing. So far I've been pleased with how this medication is helping my chronic sinus infection, but I haven't been on it for long enough to say for sure.

3.7

Patient Review

7/15/2021

Cefdinir for Middle Ear Infection

I've been taking this medication twice a day as instructed. I don't love that it has to be taken with food, but so far so good in terms of side effects.

2.3

Patient Review

5/9/2021

Cefdinir for Bacterial Urinary Tract Infection

Bactrim worked for the first three days, but after starting Cefdinir, I feel like the UTI is getting worse again.

2

Patient Review

12/2/2021

Cefdinir for Acute Maxillary Sinus S. Pneumoniae Bacteria Infection

My husband took this for a stubborn sinus infection and it immediately made him really sick. Severe diarrhea, dizziness, weakness, dehydration. Much worse than the infection itself - and he was sick!

1.7

Patient Review

9/20/2022

Cefdinir for Strep Throat

I took the recommended dosage and ended up with a stomachache so severe I would have preferred to get punched in the face.

1

Patient Review

2/23/2022

Cefdinir for Acute Maxillary Sinus S. Pneumoniae Bacteria Infection

Cefdinir gave me heartburn that has not gone away since I quit taking it 5 days ago.

1

Patient Review

6/1/2021

Cefdinir for infection caused by bacteria

Took one pill and got severe diarrhea almost immediately. Never again.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cefdinir

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is cefdinir the same thing as amoxicillin?

"Amoxicillin is available as a generic and as the brand-name drugs Amoxil and Moxatag.

Cefdinir and amoxicillin are used to treat bacterial infections. Cefdinir is a cephalosporin antibiotic, while amoxicillin is a penicillin-type antibiotic. Cefdinir is available only as a generic, while amoxicillin is available as a generic and under the brand names Amoxil and Moxatag."

Answered by AI

Is cefdinir strong antibiotic?

"Does cefdinir treat a lot of different types of bacteria? Cefdinir is an "extended spectrum" antibiotic, which means that it works against a good number of bacteria. There are other antibiotics that can treat more types of infections, or more serious infections."

Answered by AI

Is cefdinir stronger than amoxicillin?

"Although some clinical trials in the United States and Europe have found that cefdinir is just as effective as amoxicillin/clavulanate when treating bacterial sinusitis, cefdinir was shown to be more effective after 10 days of treatment."

Answered by AI

What is cefdinir used to treat?

"Cefdinir is an antibiotic used to treat bacterial infections. It belongs to the class of cephalosporin antibiotics and works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections."

Answered by AI

Clinical Trials for Cefdinir

Image of Children's Healthcare of Atlanta in Atlanta, United States.

Antibiotic Strategies for Pneumonia in Children

12 - 71
All Sexes
Atlanta, GA

The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring that children diagnosed with community-acquired pneumonia get better from their illness. The main aims of this study are: * To compare the effectiveness of SNAP versus immediate antibiotic prescribing in children with mild community-acquired pneumonia (CAP) * To identify which patient groups benefit most from the SNAP strategy * To identify factors that shape implementation of each prescribing strategy. Researchers will compare the SNAP strategy (where parents or guardians are instructed to give antibiotics only if their child is not improving after 72 hours, or sooner if they are worsening) to the immediate antibiotic prescribing strategy (where parents or guardians are instructed to give the antibiotics right after their healthcare visit) to see if one strategy is more effective than the other. Participants will be randomly assigned to either the immediate antibiotic group or the SNAP group at enrollment. Participation lasts 14 days with follow-up surveys at 4, 7, and 14 days after enrollment.

Recruiting
Has No Placebo

Children's Healthcare of Atlanta (+3 Sites)

Todd Florin, MD, MSCE

Have you considered Cefdinir clinical trials?

We made a collection of clinical trials featuring Cefdinir, we think they might fit your search criteria.
Go to Trials
Image of Boston Children's Hospital in Waltham, United States.

Opioid-Sparing Anesthesia for Pediatric Tonsil Surgery

3 - 17
All Sexes
Waltham, MA

This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondary measures include rescue opioids administered in post-anesthesia care unit (PACU), re-operation secondary to bleeding, emergence delirium, post-operative nausea and vomiting, intraoperative hemodynamics, intraoperative vasopressor administration, and length of procedure.

Recruiting
Has No Placebo

Boston Children's Hospital