Cefdinir

Moraxella catarrhalis, Tonsillitis, Tonsillitis + 19 more
Treatment
22 FDA approvals
9 Active Studies for Cefdinir

What is Cefdinir

CefdinirThe Generic name of this drug
Treatment SummaryCefdinir, also known as Omnicef, is an antibiotic used to treat a wide range of bacterial infections in the ear, sinus, throat, lungs, and skin. It was approved by the FDA in 1997 and works by blocking the production of beta-lactamase enzymes which can make some bacteria resistant to first-line cephalosporin therapy. Cefdinir is a broad-spectrum antibiotic and is generally very effective and well-tolerated.
Omnicefis the brand name
image of different drug pills on a surface
Cefdinir Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Omnicef
Cefdinir
1997
175

Approved as Treatment by the FDA

Cefdinir, also known as Omnicef, is approved by the FDA for 22 uses including Bronchitis and Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza .
Bronchitis
Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza
Acute exacerbation of chronic bronchitis caused by Haemophilus parainfluenzae
Maxillary Sinusitis
Tonsillitis
Bronchitis, Chronic
Haemophilus parainfluenzae
Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
Haemophilus influenzae
Tonsillitis streptococcal
Haemophilus influenzae
Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
Acute maxillary sinusitis caused by H. influenzae
Streptococcal Pharyngitis
acute otitis media caused by S.pneumoniae
Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae
Moraxella catarrhalis
Acute maxillary sinusitis caused by M. catarrhalis
Moraxella catarrhalis
Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
Bronchitis
Moraxella catarrhalis

Effectiveness

How Cefdinir Affects PatientsCefdinir is a drug used to treat bacterial infections by stopping the bacteria from creating new cell walls. It has a broad range of effectiveness against both gram-positive and gram-negative bacteria, and is even strong enough to fight against bacteria with beta-lactamase enzymes, which can make them resistant to other cephalosporins.
How Cefdinir works in the bodyCefdinir is an antibiotic with a stronger ability to kill bacteria than penicillin. It works by stopping the bacteria from building their cell walls, which eventually leads to their death. Cefdinir does this by binding to proteins in the bacteria's cell wall and blocking their ability to build the wall. It also has the added benefit of being able to resist enzymes that some bacteria produce to protect themselves from antibiotics. Cefdinir has been shown to target certain proteins in bacteria, but it is unclear how this contributes to its effectiveness.

When to interrupt dosage

The proposed dose of Cefdinir is hinged on the determined sickness, including Communicable Diseases, Bronchitis and Haemophilus parainfluenzae. The measure of dosage is contingent upon the management methodology (e.g. Capsule or Capsule - Oral) delineated in the accompanying table.
Condition
Dosage
Administration
Bronchitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Bronchitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Moraxella catarrhalis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Haemophilus influenzae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Bronchitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Moraxella catarrhalis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Sinusitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Bronchitis, Chronic
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
acute otitis media caused by S.pneumoniae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Communicable Diseases
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Maxillary Sinusitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Acute maxillary sinusitis caused by M. catarrhalis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Haemophilus parainfluenzae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Haemophilus influenzae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Tonsillitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Tonsillitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Streptococcal Pharyngitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral

Warnings

Cefdinir Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Cefdinir may interact with Pulse Frequency
There are 20 known major drug interactions with Cefdinir.
Common Cefdinir Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefdinir.
Abacavir
Minor
Cefdinir may decrease the excretion rate of Abacavir which could result in a higher serum level.
Abciximab
Minor
The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefdinir.
Aclidinium
Minor
Cefdinir may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Cefdinir may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Cefdinir Toxicity & Overdose RiskThe lowest toxic dose of cefdinir in rats is over 2000mg/kg. No side effects were reported from giving a single dose of 5600mg/kg to rodents. Symptoms of toxicity and overdose from other beta-lactam antibiotics include nausea, vomiting, diarrhea, abdominal pain, and seizures.
image of a doctor in a lab doing drug, clinical research

Cefdinir Novel Uses: Which Conditions Have a Clinical Trial Featuring Cefdinir?

Presently, there are 9 trials investigating the potential of Cefdinir to reduce Tonsillitis, Streptococcal Pharyngitis and Communicable Diseases.
Condition
Clinical Trials
Trial Phases
Streptococcal Pharyngitis
0 Actively Recruiting
Tonsillitis
4 Actively Recruiting
Phase 2, Not Applicable, Phase 4
Haemophilus influenzae
0 Actively Recruiting
Moraxella catarrhalis
0 Actively Recruiting
Haemophilus influenzae
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
0 Actively Recruiting
Sinusitis
0 Actively Recruiting
Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
0 Actively Recruiting
Maxillary Sinusitis
0 Actively Recruiting
Community Acquired Pneumonia (CAP)
5 Actively Recruiting
Not Applicable, Phase 1, Phase 3
Moraxella catarrhalis
0 Actively Recruiting
Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
0 Actively Recruiting
Acute maxillary sinusitis caused by M. catarrhalis
0 Actively Recruiting
acute otitis media caused by S.pneumoniae
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Haemophilus parainfluenzae
0 Actively Recruiting
Moraxella catarrhalis
0 Actively Recruiting
Bronchitis, Chronic
0 Actively Recruiting

Cefdinir Reviews: What are patients saying about Cefdinir?

5Patient Review
9/27/2022
Cefdinir for Bacterial Urinary Tract Infection
I took this medication on a full stomach with no problems whatsoever. I would definitely recommend it to others who might have a sensitive stomach.
5Patient Review
10/18/2022
Cefdinir for Bacterial Urinary Tract Infection
Despite being a bit hesitant due to other reviews, I decided to give this medication a try for my recurrent UTI issue. Thankfully, it worked like a charm and I haven't had any issues since!
4Patient Review
9/30/2022
Cefdinir for infection caused by bacteria
Though the taste of the pills was vile, this medication was very effective.
3.7Patient Review
8/9/2021
Cefdinir for Acute Maxillary Sinus S. Pneumoniae Bacteria Infection
It's important to take probiotics and eat yogurt while you're taking this antibiotic, in order to stop a yeast infection from developing. So far I've been pleased with how this medication is helping my chronic sinus infection, but I haven't been on it for long enough to say for sure.
3.7Patient Review
7/15/2021
Cefdinir for Middle Ear Infection
I've been taking this medication twice a day as instructed. I don't love that it has to be taken with food, but so far so good in terms of side effects.
2.3Patient Review
5/9/2021
Cefdinir for Bacterial Urinary Tract Infection
Bactrim worked for the first three days, but after starting Cefdinir, I feel like the UTI is getting worse again.
2Patient Review
12/2/2021
Cefdinir for Acute Maxillary Sinus S. Pneumoniae Bacteria Infection
My husband took this for a stubborn sinus infection and it immediately made him really sick. Severe diarrhea, dizziness, weakness, dehydration. Much worse than the infection itself - and he was sick!
1.7Patient Review
9/20/2022
Cefdinir for Strep Throat
I took the recommended dosage and ended up with a stomachache so severe I would have preferred to get punched in the face.
1Patient Review
2/23/2022
Cefdinir for Acute Maxillary Sinus S. Pneumoniae Bacteria Infection
Cefdinir gave me heartburn that has not gone away since I quit taking it 5 days ago.
1Patient Review
6/1/2021
Cefdinir for infection caused by bacteria
Took one pill and got severe diarrhea almost immediately. Never again.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cefdinir

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is cefdinir the same thing as amoxicillin?

"Amoxicillin is available as a generic and as the brand-name drugs Amoxil and Moxatag.

Cefdinir and amoxicillin are used to treat bacterial infections. Cefdinir is a cephalosporin antibiotic, while amoxicillin is a penicillin-type antibiotic. Cefdinir is available only as a generic, while amoxicillin is available as a generic and under the brand names Amoxil and Moxatag."

Answered by AI

Is cefdinir strong antibiotic?

"Does cefdinir treat a lot of different types of bacteria? Cefdinir is an "extended spectrum" antibiotic, which means that it works against a good number of bacteria. There are other antibiotics that can treat more types of infections, or more serious infections."

Answered by AI

Is cefdinir stronger than amoxicillin?

"Although some clinical trials in the United States and Europe have found that cefdinir is just as effective as amoxicillin/clavulanate when treating bacterial sinusitis, cefdinir was shown to be more effective after 10 days of treatment."

Answered by AI

What is cefdinir used to treat?

"Cefdinir is an antibiotic used to treat bacterial infections. It belongs to the class of cephalosporin antibiotics and works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections."

Answered by AI

Clinical Trials for Cefdinir

Image of Children's Healthcare of Atlanta in Atlanta, United States.

Antibiotic Strategies for Pneumonia in Children

12 - 71
All Sexes
Atlanta, GA
The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring that children diagnosed with community-acquired pneumonia get better from their illness. The main aims of this study are: * To compare the effectiveness of SNAP versus immediate antibiotic prescribing in children with mild community-acquired pneumonia (CAP) * To identify which patient groups benefit most from the SNAP strategy * To identify factors that shape implementation of each prescribing strategy. Researchers will compare the SNAP strategy (where parents or guardians are instructed to give antibiotics only if their child is not improving after 72 hours, or sooner if they are worsening) to the immediate antibiotic prescribing strategy (where parents or guardians are instructed to give the antibiotics right after their healthcare visit) to see if one strategy is more effective than the other. Participants will be randomly assigned to either the immediate antibiotic group or the SNAP group at enrollment. Participation lasts 14 days with follow-up surveys at 4, 7, and 14 days after enrollment.
Recruiting
Has No Placebo
Children's Healthcare of Atlanta (+3 Sites)Todd Florin, MD, MSCE
Have you considered Cefdinir clinical trials? We made a collection of clinical trials featuring Cefdinir, we think they might fit your search criteria.Go to Trials
Image of Boston Children's Hospital in Waltham, United States.

Opioid-Sparing Anesthesia for Pediatric Tonsil Surgery

3 - 17
All Sexes
Waltham, MA
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondary measures include rescue opioids administered in post-anesthesia care unit (PACU), re-operation secondary to bleeding, emergence delirium, post-operative nausea and vomiting, intraoperative hemodynamics, intraoperative vasopressor administration, and length of procedure.
Recruiting
Has No Placebo
Boston Children's Hospital
Image of Loma Linda University Professional Building - Murrieta in Murrieta, United States.

Lateral Pharyngoplasty + Tonsillectomy for Tonsillitis

3 - 17
All Sexes
Murrieta, CA
The goal of this treatment study is to determine if doing lateral pharyngoplasty with tonsillectomy is better for children than doing tonsillectomy alone. The main questions it aims to answer are: * Do children experience less pain after surgery when lateral pharyngoplasty is performed with tonsillectomy compared to tonsillectomy alone? * Do children eat/drink better when lateral pharyngoplasty is performed with tonsillectomy compared to tonsillectomy alone? * Is there a lower risk of bleeding after tonsillectomy when lateral pharyngoplasty is performed? Researchers will compare children undergoing tonsillectomy and lateral pharyngoplasty with children undergoing tonsillectomy alone to see if the participants experience less pain, better oral intake, and less bleeding complications after surgery. Parents of participants will be asked to record pain scores and pain medications given, approximate amounts of daily oral intake, and any complications after surgery.
Recruiting
Has No Placebo
Loma Linda University Professional Building - Murrieta (+3 Sites)Tsungju O-Lee, MD
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