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Cancer Vaccine

Trivalent Salmonella Conjugate Vaccine (TSCV) Full-Strength Formulation for Risk Reduction

Phase 1
Waitlist Available
Research Sponsored by University of Maryland, Baltimore
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately six months
Awards & highlights

Study Summary

This trial will test a new vaccine for Salmonella, testing how well it works and if it is safe.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately six months
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately six months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Frequency and Severity of Solicited Local and Systemic Adverse Events (AEs)
Frequency and Severity of Unsolicited AEs and Serious Adverse Events (SAEs)
Proportion of Responders

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Group C: Dilutional Half-Strength FormulationExperimental Treatment1 Intervention
Individuals receive one dose of dilutional half-strength Trivalent Salmonella Conjugate Vaccine (TSCV). Subsequent blood samples are taken for safety and immunological testing.
Group II: Group B: Half-Strength FormulationExperimental Treatment1 Intervention
Individuals receive one dose of half-strength Trivalent Salmonella Conjugate Vaccine (TSCV). Subsequent blood samples are taken for safety and immunological testing.
Group III: Group A: Full-Strength FormulationExperimental Treatment1 Intervention
Individuals receive one dose of full-strength Trivalent Salmonella Conjugate Vaccine (TSCV). Subsequent blood samples are taken for safety and immunological testing.
Group IV: Group D: PlaceboPlacebo Group1 Intervention
Individuals receive one dose of placebo. Subsequent blood samples are taken for safety and immunological testing.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Trivalent Salmonella Conjugate Vaccine (TSCV) Full-Strength Formulation
2022
Completed Phase 1
~90
Trivalent Salmonella Conjugate Vaccine (TSCV) Half-Strength Formulation
2022
Completed Phase 1
~90
Trivalent Salmonella Conjugate Vaccine (TSCV) Dilutional Half-Strength Formulation
2022
Completed Phase 1
~90

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

University of Maryland, BaltimoreLead Sponsor
687 Previous Clinical Trials
374,564 Total Patients Enrolled
2 Trials studying Risk Reduction
246 Patients Enrolled for Risk Reduction
Myron M Levine, MD, DTPHStudy DirectorUniversity of Maryland, Baltimore
2 Previous Clinical Trials
4,284 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current recruitment size for this clinical trial?

"Affirmative. Clinicaltrials.gov verifies that this clinical trial, which was first announced on August 15th 2022, is actively seeking participants. The researchers are looking for 80 patients at a single medical facility."

Answered by AI

Is there an ongoing recruitment process for this research trial?

"Affirmative. Clinicaltrials.gov records indicate that this clinical trial, posted on August 15th 2022, is proactively recruiting individuals for participation. 80 subjects are being accepted at 1 medical facility."

Answered by AI

Who is eligible to register for this research study?

"For this trial, 80 participants aged 18-49 who are at risk of reduction must be recruited. These individuals should also meet the following requirements: female candidates of childbearing potential need to agree to acceptable birth control measures; demonstrate an ability to provide written informed consent; present good general health as determined by vitals and medical history (including a physical examination within 45 days prior); display expressed interest in fulfilling study requisites; abstain from participating in other clinical trials throughout the duration of the experiment; and allow for indefinite storage of stored blood samples used for research purposes."

Answered by AI

Does this research initiative accept participants aged 50 or above?

"This clinical trial has stipulated that participants must be between 18 and 49 years old, as indicated by the established inclusion criteria."

Answered by AI

Has the Trivalent Salmonella Conjugate Vaccine (TSCV) Full-Strength Formulation achieved regulatory approval?

"The estimated safety of Trivalent Salmonella Conjugate Vaccine (TSCV) Full-Strength Formulation is a 1 due to the lack of empirical evidence supporting its efficacy and security, as this trial is in Phase 1."

Answered by AI
~31 spots leftby Apr 2025