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What is Cardura
DoxazosinThe Generic name of this drug
Treatment SummaryDoxazosin is a prescription drug used to treat high blood pressure and symptoms of an enlarged prostate. It belongs to a class of medications called alpha-1 antagonists and works by relaxing the muscles in the bladder and prostate. Doxazosin was approved by the FDA in 1990 and is made by Pfizer. It can be taken once daily and has long-lasting effects.
Cardurais the brand name
Cardura Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cardura
Doxazosin
1991
281
Approved as Treatment by the FDA
Doxazosin, commonly known as Cardura, is approved by the FDA for 1 uses which include Hypertensive disease .Hypertensive disease
Effectiveness
How Cardura Affects PatientsDoxazosin is used to lower blood pressure and treat symptoms of an enlarged prostate. Taking this drug can cause dizziness or lightheadedness, especially when you first start taking it or if there are long breaks between doses. It is important to slowly increase the dose, beginning with the lowest (1 mg). Doxazosin can also have positive effects on cholesterol levels, reducing LDL and triglycerides and increasing HDL. Rarely, doxazosin may cause priapism, a painful condition of long-lasting erections that can eventually lead to impotence. If you suspect you have priapism,
How Cardura works in the bodyDoxazosin works by blocking receptors in blood vessels, reducing the amount of pressure in your blood. It also relaxes the muscles around your prostate and bladder neck, helping to reduce symptoms of Benign Prostatic Hyperplasia (BPH). Although it can help with BPH, there is a risk of heart failure associated with doxazosin use.
When to interrupt dosage
The recommended measure of Cardura is contingent upon the documented condition, for instance Enlarged Prostate, Ureteric calculus and Hypertensive disease. The amount likewise deviates based on the method of administration, as shown in the table below.Condition
Dosage
Administration
Hypertensive disease
, 4.0 mg, 8.0 mg, 1.0 mg, 2.0 mg, 5.1 mg, 10.2 mg
, Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, Tablet - Oral, Kit; Tablet, Kit; Tablet - Oral
Enlarged Prostate
, 4.0 mg, 8.0 mg, 1.0 mg, 2.0 mg, 5.1 mg, 10.2 mg
, Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, Tablet - Oral, Kit; Tablet, Kit; Tablet - Oral
Ureteric calculus
, 4.0 mg, 8.0 mg, 1.0 mg, 2.0 mg, 5.1 mg, 10.2 mg
, Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, Tablet - Oral, Kit; Tablet, Kit; Tablet - Oral
Warnings
Cardura ContraindicationsCondition
Risk Level
Notes
Quinazolines
Do Not Combine
Common Cardura Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Doxazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Doxazosin may increase the hypotensive activities of Alfuzosin.
Amifostine
Major
Doxazosin may increase the hypotensive activities of Amifostine.
Aripiprazole
Major
Doxazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Doxazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Cardura Toxicity & Overdose RiskThe lowest toxic dose of doxazosin for mice is greater than 1000mg/kg. Signs of overdosing on doxazosin include low blood pressure, changes in heartbeat, and sleepiness. Treatment for overdoses includes supportive care, removing unabsorbed doxazosin from the stomach, correcting low blood pressure, and closely monitoring vital signs.
Cardura Novel Uses: Which Conditions Have a Clinical Trial Featuring Cardura?
39 active trials are being conducted to evaluate the potential of Cardura to provide relief from Enlarged Prostate, Ureteric calculus and Hypertension.Condition
Clinical Trials
Trial Phases
Ureteric calculus
0 Actively Recruiting
Enlarged Prostate
21 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Cardura Reviews: What are patients saying about Cardura?
5Patient Review
2/26/2017 At long last, I've found a medication that helps with my high blood pressure!
5Patient Review
3/19/2014 This drug, in combination with Avodart and Bethanechol, has been highly effective for my prostate.
5Patient Review
1/11/2014 This medication unfortunately had a lot of negative side effects for me, including an increase in blood pressure and shortness of breath. I wouldn't recommend it to others.
4.7Patient Review
6/20/2012 I'm taking this for migraines, and it's been two days without any issues. Even with some specific triggers, I haven't gotten a migraine. So far no side effects & I don't have to worry about a prostate.
4.3Patient Review
6/6/20114Patient Review
10/12/2013 I had to stop taking this medication after only six weeks because the side effects were becoming too much to bear. I was constantly tired, my mouth was dry, and I felt unbalanced. The swelling got so bad that it was difficult to talk. If you're considering this as a last resort, be aware of the possible consequences.
3.7Patient Review
9/25/2014 I developed severe swelling in my ankles while taking this medication but I'm not sure if the two are related.
3Patient Review
6/24/2011 I've been taking 4mg of Cardura for over 10 years. I tried stopping, but my blood pressure went up. Once I started taking it again, everything returned to normal. In addition to controlling my BP, this medication has also helped me limit the number of times I need to urinate in the evening.
3Patient Review
6/7/20112.3Patient Review
8/9/2019 I was prescribed Cardura years ago for BPH, but at the time I didn't have a lot of knowledge about the condition. Every time I would bend down, I would get dizzy and my blood pressure would drop extremely low. My doctor ignored my concerns at the time.
2.3Patient Review
8/11/2014 Unfortunately, this little white pill also gave me terrible side effects like stomach pain and gas, chest cramps, and wheezing lungs.
2Patient Review
1/11/2012 My blood pressure has been more stable since taking this medication, but now I have to deal with swollen ankles.
1.7Patient Review
3/6/2013 I initially started having hot flushes about four times a day, but now they've increased to every two hours. Additionally, my vision has become blurry.
1Patient Review
11/28/2013 I was treated for prostate cancer in 1996. After treatment I experienced urination frequency and voiding problems. I have been on 4 to 8 milligrams of Cardura per day ever since. I have not noticed any severe side effects, but am more tired than I think I should be.
Patient Q&A Section about cardura
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Cardura a beta blocker?
"Cardura is an alpha-1 adrenergic blocker that is prescribed for treating high blood pressure and symptoms associated with benign prostatic hyperplasia."
Answered by AI
What is the drug Cardura used for?
"Doxazosin is used to lower blood pressure. It may be used alone or with other blood pressure lowering medications. This medication works by relaxing blood vessels so blood flows more easily."
Answered by AI
What are the side effects of taking doxazosin?
"If you are feeling weak, sleepy, or dizzy, you may have a headache. Your feet, ankles, or fingers may be swollen. You may have a urinary tract infection (UTI) or cystitis. You may have stomach pain or back pain. You may feel sick (nausea), have indigestion, or heartburn."
Answered by AI
Does Cardura lower blood pressure?
"Cardura leads to lower blood pressure and may trigger dizziness or fainting, most notably when you first start taking it, or when you start taking it again after a break. You may feel very dizzy when you first wake up in the morning. Be cautious when standing or sitting up from a lying position."
Answered by AI