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Imaging Technique

Imaging Techniques for Melanoma Detection

N/A
Recruiting
Led By Pamela Cassidy
Research Sponsored by OHSU Knight Cancer Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Persons age 18-80 are eligible for the study
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 1 year
Awards & highlights

Study Summary

This trial is testing how well 3 different portable imaging systems work in finding melanomas before they can spread.

Who is the study for?
This trial is for people aged 18-80 who have been recommended a biopsy for a suspicious mole during free skin cancer screenings at OHSU or identified through OHSU Dermatology clinics. It's also open to those with benign or atypical nevi for imaging only. Participants must be able to consent, and most are expected to be Non-Hispanic whites due to melanoma prevalence.Check my eligibility
What is being tested?
The study tests the effectiveness of MoleMapper, Visiomed, and confocal microscopy in detecting melanoma compared to traditional dermatologist examinations. These portable imaging techniques may help identify melanomas early without an office visit.See study design
What are the potential side effects?
Potential side effects mainly involve the biopsy procedures which can include discomfort from lidocaine injection and minor bleeding, bruising, or infection at the biopsy site. Allergic reactions to lidocaine are possible but participants with such allergies are excluded.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 80 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Sensitivity of the imaging modalities
Specificity of imaging modalities
Secondary outcome measures
Sensitivity by changes after consideration of in vivo reflectance mode confocal scanning laser microscopy (RCM) report
Specificity by changes after consideration of RCM report
Other outcome measures
Improvements in virtual triage of patients when enabling patients to take and submit digital dermoscopy images from home

Trial Design

1Treatment groups
Experimental Treatment
Group I: Screening (imaging, biopsy)Experimental Treatment6 Interventions
Participants undergo imaging of suspicious moles via smartphone app MoleMapper/Sklip app/native smartphone camera app, digital dermoscopy, and confocal microscopy. Participants then receive lidocaine SC and undergo shave or punch biopsy of suspected melanomas.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lidocaine
2011
Completed Phase 4
~1360
Punch Biopsy
2017
N/A
~40

Find a Location

Who is running the clinical trial?

OHSU Knight Cancer InstituteLead Sponsor
230 Previous Clinical Trials
2,090,626 Total Patients Enrolled
Oregon Health and Science UniversityOTHER
973 Previous Clinical Trials
7,385,712 Total Patients Enrolled
Pamela CassidyPrincipal InvestigatorOHSU Knight Cancer Institute
1 Previous Clinical Trials
6 Total Patients Enrolled

Media Library

Confocal Microscopy (Imaging Technique) Clinical Trial Eligibility Overview. Trial Name: NCT03699995 — N/A
Skin Cancer Research Study Groups: Screening (imaging, biopsy)
Skin Cancer Clinical Trial 2023: Confocal Microscopy Highlights & Side Effects. Trial Name: NCT03699995 — N/A
Confocal Microscopy (Imaging Technique) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03699995 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants younger than 55 years of age acceptable for this research?

"Based on the prerequisites for this experiment, participants must be between 18 and 80 years old."

Answered by AI

What clinical conditions could be treated with the help of Confocal Microscopy?

"Confocal Microscopy is a technique employed to treat cervical syndrome, minor burn incidents and transplantation operations."

Answered by AI

What findings have been previously established through Confocal Microscopy?

"As of now, 119 clinical trials focusing on the use of Confocal Microscopy in medical treatment are underway. 31 of those studies have already progressed to their final phase, with most being located in Calgary, Alberta and a total 1096 sites running relevant research."

Answered by AI

Is this research project actively seeking participants at the moment?

"Indeed, according to clinicaltrials.gov the trial is currently open for enrollment. It was first uploaded on May 18th 2018 and most recently updated on October 17th 2022. The study seeks 100 patients from a single site."

Answered by AI

Are there any certain individuals that are more suitable for this medical research?

"This research endeavour is taking in 100 individuals between the ages of 18 and 80 who have carcinoma. Qualified participants must meet a few requirements, such as having gone through the free skin cancer screening at either the PDX Skincare Festival or War on Skin Cancer event hosted by Oregon Health & Science University (OHSU) during 2021/2022; being informed by an OHSU provider that they have a pigmented lesion for which biopsy is recommended; age range between 18-80; being identified in OHSU Dermatology clinics or via e-visit and e-consult platforms with need of skin"

Answered by AI

What is the total number of participants involved in this experiment?

"Affirmative. The information held on clinicaltrials.gov demonstrates that this medical experiment, which was first published on May 18th 2018, is still open for enrolment. A total of 100 participants are needed to be recruited from one centre."

Answered by AI

Who else is applying?

What state do they live in?
Washington
How old are they?
18 - 65
What site did they apply to?
OHSU Knight Cancer Institute
What portion of applicants met pre-screening criteria?
Met criteria
~26 spots leftby May 2026