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What is Carboprost Tromethamine
Carboprost tromethamineThe Generic name of this drug
Treatment SummaryA non-steroid drug that is used to induce an abortion during the first and second trimesters of pregnancy.
Hemabateis the brand name
Carboprost Tromethamine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hemabate
Carboprost tromethamine
1979
8
Effectiveness
How Carboprost Tromethamine Affects PatientsCarboprost tromethamine is a drug that, when injected, causes contractions in the uterus similar to labor contractions, which help to remove the baby from the womb. It also helps to stop bleeding after birth. It may cause vomiting, diarrhea, and a temporary rise in body temperature when used to end a pregnancy or after childbirth. When taken in large doses, it can raise blood pressure, body temperature and cause bronchoconstriction (narrowing of the airways) in some patients.
How Carboprost Tromethamine works in the bodyCarboprost is a synthetic drug that mimics the effects of a natural hormone called prostaglandin. It attaches to the same receptors as prostaglandin, and causes the muscles of the uterus to contract. This is useful for inducing labor or expelling the placenta.
When to interrupt dosage
The recommended dose of Carboprost Tromethamine is dependent upon the diagnosed situation, including Pregnancy, unrelenting Postpartum Haemorrhage (PPH) instigated by Uterine Atony and Therapeutic procedure. The measure of dosage vacillates, in line with the administration technique noted in the table below.Condition
Dosage
Administration
Therapeutic procedure
, 0.25 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Injection, solution, Injection, solution - Intramuscular
unresponsive Postpartum Haemorrhage (PPH) caused by Uterine Atony
, 0.25 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Injection, solution, Injection, solution - Intramuscular
Warnings
There are 11 known major drug interactions with Carboprost Tromethamine.Common Carboprost Tromethamine Drug Interactions
Drug Name
Risk Level
Description
Carbetocin
Major
Carboprost tromethamine may increase the uterotonic activities of Carbetocin.
Demoxytocin
Major
Carboprost tromethamine may increase the uterotonic activities of Demoxytocin.
Dinoprost
Major
Carboprost tromethamine may increase the uterotonic activities of Dinoprost.
Dinoprost tromethamine
Major
Carboprost tromethamine may increase the uterotonic activities of Dinoprost tromethamine.
Dinoprostone
Major
Carboprost tromethamine may increase the uterotonic activities of Dinoprostone.
Carboprost Tromethamine Toxicity & Overdose RiskOverdosing on Benadryl may lead to irritation, nausea, vomiting, diarrhea, coughing, shortness of breath, asthma-like symptoms, high blood pressure, redness of the skin, and fever.
Carboprost Tromethamine Novel Uses: Which Conditions Have a Clinical Trial Featuring Carboprost Tromethamine?
43 active clinical trials are presently underway to investigate the potential of Carboprost Tromethamine for use in Pregnancy, to address unresponsive Postpartum Haemorrhage (PPH) caused by Uterine Atony and for Therapeutic purposes.Condition
Clinical Trials
Trial Phases
unresponsive Postpartum Haemorrhage (PPH) caused by Uterine Atony
0 Actively Recruiting
Therapeutic procedure
1 Actively Recruiting
Phase 3
Carboprost Tromethamine Reviews: What are patients saying about Carboprost Tromethamine?
4Patient Review
2/6/2008Patient Q&A Section about carboprost tromethamine
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is carboprost tromethamine used for?
"Hemabate is a form of prostaglandin that is used to treat severe postpartum bleeding and to induce abortions."
Answered by AI
What is carboprost tromethamine used for in pregnancy?
"Carboprost tromethamine is a prostaglandin that is used to treat postpartum uterine hemorrhage due to atony. It is an abortifacient agent that is effective in both the first and second trimesters of pregnancy."
Answered by AI
What class of drug is carboprost?
"This drug belongs to a group of drugs called prostaglandins. These drugs work by causing contractions in the uterus."
Answered by AI
What are the contraindications of carboprost tromethamine?
"...
If you are aborting a pregnancy, have had trauma, or are going to have surgery, carboprost tromethamine may be used. However, strict adherence to recommended dosages is necessary, and people who are allergic to Benzyl alcohol should not use this. Additionally, this should not be used if there is an infection present or if the person has cardiac disease or hypertension. Finally, asthma or pulmonary disease may also be a contraindication for use of carboprost tromethamine."
Answered by AI