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What is Bydureon
ExenatideThe Generic name of this drug
Treatment SummaryExenatide is a medication that helps to control blood sugar levels. It works by activating a receptor in the body that increases insulin production, decreases the amount of glucagon in the body, and slows down the emptying of the stomach. Exenatide was approved by the FDA in 2005 and is prescribed to people with diabetes.
Byettais the brand name
Bydureon Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Byetta
Exenatide
2005
10
Effectiveness
How Bydureon Affects PatientsExenatide helps to regulate the body's response to glucose, releasing more insulin and less glucagon when it is needed. This helps to prevent dangerously high or low blood sugar levels. It also slows down how quickly the stomach empties, meaning that the glucose enters the body's system more slowly. This further helps to prevent dangerous spikes or drops in blood sugar levels.
How Bydureon works in the bodyExenatide is a drug that helps control blood sugar levels. It works by activating a receptor in the body that stimulates insulin production, while reducing glucagon production. It also slows down digestion and reduces food intake, helping to prevent episodes of high or low blood sugar.
When to interrupt dosage
The measure of Bydureon is contingent upon the identified affliction. The amount of dosage fluctuates as per the technique of administration cited in the table beneath.Condition
Dosage
Administration
Physical Activity
, 0.25 mg/mL, 0.005 mg, 0.01 mg, 2.0 mg, 20.0 mg/mL, 2.0 mg/dose, 0.005 mg/pump actuation, 0.01 mg/pump actuation
, Subcutaneous, Injection, Injection - Subcutaneous, Kit, Injection, solution, Injection, solution - Subcutaneous, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Subcutaneous, Solution, Solution - Subcutaneous, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Subcutaneous, Injection, suspension, extended release, Injection, suspension, extended release - Subcutaneous, Suspension, extended release, Suspension, extended release - Subcutaneous
Diet
, 0.25 mg/mL, 0.005 mg, 0.01 mg, 2.0 mg, 20.0 mg/mL, 2.0 mg/dose, 0.005 mg/pump actuation, 0.01 mg/pump actuation
, Subcutaneous, Injection, Injection - Subcutaneous, Kit, Injection, solution, Injection, solution - Subcutaneous, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Subcutaneous, Solution, Solution - Subcutaneous, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Subcutaneous, Injection, suspension, extended release, Injection, suspension, extended release - Subcutaneous, Suspension, extended release, Suspension, extended release - Subcutaneous
Type 2 Diabetes
, 0.25 mg/mL, 0.005 mg, 0.01 mg, 2.0 mg, 20.0 mg/mL, 2.0 mg/dose, 0.005 mg/pump actuation, 0.01 mg/pump actuation
, Subcutaneous, Injection, Injection - Subcutaneous, Kit, Injection, solution, Injection, solution - Subcutaneous, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Subcutaneous, Solution, Solution - Subcutaneous, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Subcutaneous, Injection, suspension, extended release, Injection, suspension, extended release - Subcutaneous, Suspension, extended release, Suspension, extended release - Subcutaneous
Warnings
Bydureon ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Exenatide may interact with Pulse Frequency
Common Bydureon Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Moderate
Exenatide can cause an increase in the absorption of (R)-warfarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
(S)-Warfarin
Moderate
Exenatide can cause an increase in the absorption of (S)-Warfarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
2,4-thiazolidinedione
Moderate
The risk or severity of hypoglycemia can be increased when Exenatide is combined with 2,4-thiazolidinedione.
4-hydroxycoumarin
Moderate
Exenatide can cause an increase in the absorption of 4-hydroxycoumarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
AICA ribonucleotide
Moderate
The risk or severity of hypoglycemia can be increased when Exenatide is combined with AICA ribonucleotide.
Bydureon Toxicity & Overdose RiskAnimal studies have linked exenatide to birth defects in the rib cage and spine, as well as slowed growth. Uncontrolled high blood sugar can increase the risk of miscarriage in humans by up to 25%. There are no human studies on the effects of exenatide during pregnancy, so the drug should only be taken if the benefits outweigh the risks. Exenatide is found in mouse milk at a concentration of 2.5% of the plasma, though this may not apply to humans. There is also no data on its effects on breastfed infants. Exenatide is not recommended for pediatric or geriatric patients.
Bydureon Novel Uses: Which Conditions Have a Clinical Trial Featuring Bydureon?
162 active studies are actively evaluating the utility of Bydureon in the management of Type 2 Diabetes.Condition
Clinical Trials
Trial Phases
Physical Activity
39 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Early Phase 1
Type 2 Diabetes
192 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1, Phase 1, Phase 4, Phase 3
Diet
5 Actively Recruiting
Not Applicable
Bydureon Reviews: What are patients saying about Bydureon?
5Patient Review
2/16/2018 I've only been taking this medication for a short while, but I have already seen some results. My appetite has increased and my blood sugar is more stable. I also experienced headaches at first, but they went away after a few days.
5Patient Review
9/14/2018 I've been on this medication for around four months and it has helped me lose 33 pounds gradually, which is exactly what I needed. My blood sugar levels are now more consistent and I haven't had any major issues with nausea or hunger. This has been a great experience overall.
5Patient Review
4/27/2019 I've been really pleased with how this medication has worked. My blood sugar levels have decreased so much that I barely need any insulin now. The only downside is that my appetite is suppressed and I've lost some weight, but I'll take those results any day!
5Patient Review
9/14/2018 This medication has helped me lose a significant amount of weight. I've been on it for 4 months and have lost 33 pounds (7 per month, on average). My blood sugar is now more consistent, and I've had to reduce my intake of other medications as a result. The only downside is that I sometimes experience nausea, but it's manageable with medication.
5Patient Review
4/27/2019 So far, I've been really pleased with how this medication has worked. My blood sugar has decreased to the point where I barely need any insulin at all. The only downside is that my appetite is suppressed and I've lost some weight, but those are pretty minor complaints in comparison to the benefits.
5Patient Review
12/15/2017 Though there was some oozing and a lump at the injection site for a couple weeks, this medication has really helped me cut back my urge to eat by about 60%.
5Patient Review
2/16/2018 I've only been taking this medication for a short while, but I can already tell it's making a difference. My appetite is better and my blood sugar isn't spiking as much. I still get headaches occasionally, but they might be unrelated to the Bydureon.
5Patient Review
12/15/2017 I had some mild side effects with this treatment, but overall it was very effective. It's cut my urge to eat by about 60%, which has been a huge help for me.
3Patient Review
6/24/2018 I experienced some heart palpitations and an increase in my heartbeat. I also had explosive bowel movements, sore throat, decreased appetite, and weight loss. However, my glucose readings were way down and more consistent.
3Patient Review
10/29/2019 This is generally working well for me, but I have developed a rash and some bruising on my stomach. Additionally, I've lost my appetite and am feeling very full all the time.
3Patient Review
10/29/2019 This treatment is effective, but I have experienced some stomach trouble as a result. I get rashes and bruises easily, and I haven't been feeling very hungry lately.
3Patient Review
6/24/2018 This treatment has helped my glucose readings stay consistent, but I've also experienced some less desirable side effects like an increased heart rate, palpitations, explosive bowel movements, and a sore throat.
2.7Patient Review
3/17/2018 I've been using this drug for over a year now, and I have yet to see any improvement. If anything, the lumps have gotten worse, and I always feel nauseous before and after treatment. Additionally, about one out of every eight syringes is unreliable. If you are prescribed this medication, plan on spending an hour for treatment. Slow down for half an hour after injection before moving around; otherwise, the needle (which is quite large) will leak.
2.7Patient Review
3/17/2018 I've been using this for over a year now and, unfortunately, have not seen much improvement. I still get lumps and nausea both before and after treatment, about one out of every eight syringes is unreliable, and the injection site often leaks afterwards. On the plus side, it only takes an hour to do the whole process.
Patient Q&A Section about bydureon
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Bydureon a insulin?
"No, Bydureon does not contain insulin, but it does stimulate the body to produce more insulin. Is Bydureon used as a weight loss drug? No. Bydureon is not marketed as a weight loss drug, although weight loss is a common side effect."
Answered by AI
Is Ozempic better than Bydureon?
"Ozempic caused patients to have lower A1c levels and lose more weight than patients who took Bydureon or Trulicity in clinical trials. Mar 7, 2018"
Answered by AI
Is Trulicity and Bydureon the same?
"The drugs Bydureon and Trulicity both work to improve blood sugar levels in people with type 2 diabetes by mimicking the peptide hormone GLP-1."
Answered by AI
Why is Bydureon being discontinued?
"AstraZeneca announced that it will be discontinuing Bydureon (exenatide) Pen as of March 2021 due to business reasons. The discontinuation is not due to safety or efficacy issues, product quality or manufacturing concerns. Bydureon BCise® (exenatide) Pen will continue to be available."
Answered by AI
Is Bydureon an insulin?
"No, Bydureon is not the same as insulin, but it does cause the body to release more insulin. Is Bydureon used as a weight loss drug? No, it is not approved for that purpose, even though many people who use it do lose weight."
Answered by AI
Is Ozempic and Bydureon the same?
"The side effects of Bydureon include headache, itching, indigestion, and a small bump at the injection site. These side effects are different from those of Ozempic. Both Ozempic and Bydureon may interact with insulin secretagogues or insulin, as well as other oral medications taken at the same time. In addition, Bydureon may interact with warfarin."
Answered by AI
What type of insulin is Bydureon?
"Type 2 diabetes Mellitus is a condition in which the body does not provide sufficient insulin.
Bydureon is a prescription medication used to manage the symptoms of Type 2 Diabetes Mellitus. It may be used alone or with other medications. Bydureon is part of a class of drugs called Antidiabetics, Glucagon-like Peptide-1 Agonists. Type 2 Diabetes Mellitus is characterized by the body not producing enough insulin."
Answered by AI
Why was Bydureon discontinued?
"- OptumRx® today announced that it will no longer cover AstraZeneca’s Bydureon® (exenatide) Pen as of March 14, 2021, due to the drug maker’s discontinuation of the product. — This decision is not related to any safety or efficacy issues, product quality or manufacturing concerns. OptumRx will instead cover Bydureon BCise® (exenatide), which is also manufactured by AstraZeneca.
As of March 2021, AstraZeneca will be discontinuing its Bydureon Pen due to business reasons. This decision is not related to any safety or efficacy issues, product quality or manufacturing concerns. Bydureon BCise will continue to be available. As of March 14, 2021, OptumRx will no longer cover AstraZeneca's Bydureon Pen. Instead, OptumRx will cover Bydureon BCise, which is also manufactured by AstraZeneca."
Answered by AI