Aveed
Hypogonadism, Hormone Replacement Therapy, Testosterone Deficiency + 1 more
Treatment
2 Active Studies for Aveed
Treatment for
Hypogonadism
What is Aveed
Testosterone undecanoate
The Generic name of this drug
Treatment Summary
Testosterone undecanoate is a form of testosterone used to treat low testosterone levels. It comes in an intramuscular injection and as an oral capsule. It should not be used to treat age-related low testosterone levels, but only to treat conditions caused by genetics or other structural issues.
Aveed
is the brand name
Aveed Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Aveed
Testosterone undecanoate
2014
8
Effectiveness
How Aveed Affects Patients
Testosterone undecanoate is a type of hormone replacement therapy given to males when they have a shortage of testosterone. It helps to improve symptoms like low libido, difficulty getting an erection, and losing muscle and bone mass. Testosterone has been known to be abused by athletes and bodybuilders and has therefore been classified as a controlled substance in the US. Too much testosterone can cause withdrawal symptoms such as depression, fatigue, and decreased libido for weeks or months. Women who take testosterone may experience hirsutism, deepening of the voice, breast atrophy, male-pattern baldness, and menstrual irregularities. Teens taking testosterone
How Aveed works in the body
Testosterone is an important hormone for male health. It helps grow and develop male sex organs and other related characteristics, such as hair growth and body shape. When testosterone levels are low, it can lead to health issues like difficulty with sexual function and decreased muscle mass. Testosterone is broken down by the body into its active form, dihydrotestosterone (DHT). DHT binds to receptors in the body and stimulates certain genes to help with normal growth and development of male sexual organs, as well as improved sexual function, increased muscle mass, stronger bones, changes in the prostate, and changes in cholesterol levels.
When to interrupt dosage
The proposed dosage of Aveed is contingent upon the diagnosed circumstance, including Testosterone Deficiency, Hypergonadotropic Hypogonadism and Hypogonadotropic hypogonadism. The measure of dosage shifts according to the process of delivery (e.g. Oral or Capsule, liquid filled - Oral) featured in the table underneath.
Condition
Dosage
Administration
Hypogonadism
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Hormone Replacement Therapy
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Testosterone Deficiency
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Hypogonadotropic hypogonadism
40.0 mg, , 250.0 mg/mL, 237.0 mg, 158.0 mg, 198.0 mg, 112.5 mg
, Oral, Capsule, Capsule - Oral, Intramuscular, Injection, Injection - Intramuscular, Capsule, liquid filled - Oral, Capsule, liquid filled
Warnings
Aveed has four contraindications which necessitate avoiding its utilization when afflicted with any of the circumstances listed in the following table.
Aveed Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Testosterone Undecanoate may interact with Pulse Frequency
Breast Cancer
Do Not Combine
Hypogonadism
Do Not Combine
Prostate Cancer
Do Not Combine
There are 20 known major drug interactions with Aveed.
Common Aveed Drug Interactions
Drug Name
Risk Level
Description
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Testosterone undecanoate.
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Testosterone undecanoate.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Testosterone undecanoate.
Lumateperone
Major
The serum concentration of Lumateperone can be decreased when it is combined with Testosterone undecanoate.
Ranolazine
Major
The metabolism of Ranolazine can be increased when combined with Testosterone undecanoate.
Aveed Toxicity & Overdose Risk
The toxic dose of testosterone undecanoate in mice and rats is 4000mg/kg when taken orally and 2880mg/kg when taken subcutaneously. There have been reports of one acute overdose from an injectable testosterone product and one case of overdose following oral administration, but no adverse reactions were reported. An overdose should be managed by stopping the drug and providing supportive care. Abuse of anabolic androgenic steroids may lead to serious health issues such as heart attack, stroke, liver damage, and mental health problems such as depression, mania, psychosis, and aggression. Men taking testosterone may experience temporary strokes, seizures, hyp
Aveed Novel Uses: Which Conditions Have a Clinical Trial Featuring Aveed?
At present, there are 4 active clinical trials assessing the potential of Aveed to alleviate Hypergonadotropic Hypogonadism, Hypogonadotropic Hypogonadism and Testosterone Deficiency.
Condition
Clinical Trials
Trial Phases
Hormone Replacement Therapy
0 Actively Recruiting
Testosterone Deficiency
3 Actively Recruiting
Phase 2, Phase 4, Phase 1
Hypogonadism
0 Actively Recruiting
Hypogonadotropic hypogonadism
0 Actively Recruiting
Aveed Reviews: What are patients saying about Aveed?
5
Patient Review
7/30/2015
Aveed for Pituitary Hormone Deficiency
5
Patient Review
12/31/2014
Aveed for Pituitary Hormone Deficiency
Patient Q&A Section about aveed
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How often is aveed given?
"A prescription for AVEED should include a 750 mg injection on day 1, followed by a second injection 4 weeks later. After that, subsequent injections should be given every 10 weeks."
Answered by AI
What is aveed used to treat?
"AVEED® tones those adult males who have inadequate testosterone due to particular medical predicaments. AVEED® is only for adult males requiring testosterone substitution therapy, when the benefit from receiving it is greater than the risk of pulmonary oil microembolism (POME) or anaphylaxis."
Answered by AI
How long does it take for aveed to work?
"How long does it take for Aveed (testosterone undecanoate) to start working? Aveed (testosterone undecanoate) should start raising your testosterone levels after the first injection. Although your body fully absorbs the medication in about 1 week, it can take 3 to 4 months before your testosterone levels are stable."
Answered by AI
What are the side effects of Aveed?
"Common side effects of Aveed include pain or other reactions at the injection site, increased levels of PSA (prostate-specific antigen), increased levels of estradiol (a form of estrogen), low testosterone levels, fatigue, difficulty sleeping (insomnia), mood swings, and aggression."
Answered by AI