Ampicillin And Sulbactam

Bites, Human, Animal bite, Bacterial Infections + 14 more
Treatment
4 FDA approvals
20 Active Studies for Ampicillin And Sulbactam

What is Ampicillin And Sulbactam

SulbactamThe Generic name of this drug
Treatment SummarySulbactam is a medication that is used in combination with other antibiotics to prevent bacteria from destroying the effects of the antibiotic. It works by inhibiting an enzyme called beta-lactamase that is produced by bacteria.
Unasynis the brand name
image of different drug pills on a surface
Ampicillin And Sulbactam Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Unasyn
Sulbactam
1991
92

Approved as Treatment by the FDA

Sulbactam, also known as Unasyn, is approved by the FDA for 4 uses which include Bacterial Infections and Communicable Diseases .
Bacterial Infections
Used to treat Skin and Subcutaneous Tissue Bacterial Infections in combination with Ampicillin
Communicable Diseases
Used to treat Gynaecological infection in combination with Ampicillin
Urinary Tract Infection (UTI)
Used to treat Bacterial Infections in combination with Ampicillin
Intraabdominal Infections
Used to treat Intraabdominal Infections in combination with Ampicillin

Effectiveness

How Ampicillin And Sulbactam works in the bodySulbactam stops bacteria from producing an enzyme called beta-lactamase. This enzyme stops certain antibiotics from working, so stopping it from forming allows other antibiotics to work on the bacteria. Sulbactam is often combined with ampicillin, a type of antibiotic that is not effective on its own against certain bacteria. When combined with sulbactam, ampicillin can fight a wide range of bacteria that it would otherwise be unable to.

When to interrupt dosage

The recommended dosage of Ampicillin And Sulbactam is contingent upon the diagnosed condition, such as moderate Bacterial Infections, Bacterial Infections and Nosocomial Pneumonia. The measure of dosage depends upon the appliance of delivery (e.g. Injection, powder, for solution - Intramuscular; Intravenous or Injection, powder, for solution) as listed in the following table.
Condition
Dosage
Administration
Bites, Human
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Animal bite
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Postoperative Wound Infection
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Healthcare-Associated Pneumonia
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Urinary Tract Infection (UTI)
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Community Acquired Pneumonia (CAP)
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Catheter Related Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Intraabdominal Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Postoperative Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Sinusitis
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Communicable Diseases
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
moderate Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
severe Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Endocarditis
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous
Bacterial Infections
, 1000.0 mg/mL, 500.0 mg/mL, 0.5 mg/mg, 1.0 mg/mg, 125.0 mg/mL, 500.0 mg, 1000.0 mg, 5000.0 mg, 50.0 mg/mL, 100.0 mg/mL
Intramuscular; Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, , Intravenous, Injection, powder, for solution - Intravenous, Injection, powder, for suspension, Injection, powder, for suspension - Intramuscular; Intravenous

Warnings

Ampicillin And Sulbactam has one contraindication, so it is not advised to be taken when experiencing the conditions listed in the below table.Ampicillin And Sulbactam Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Ampicillin And Sulbactam.
Common Ampicillin And Sulbactam Drug Interactions
Drug Name
Risk Level
Description
Acrivastine
Minor
Sulbactam may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Sulbactam may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Sulbactam may decrease the excretion rate of Almasilate which could result in a higher serum level.
Antihemophilic factor (recombinant), PEGylated
Minor
Sulbactam may decrease the excretion rate of Antihemophilic factor (recombinant), PEGylated which could result in a higher serum level.
Antithrombin III human
Minor
Sulbactam may decrease the excretion rate of Antithrombin III human which could result in a higher serum level.
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Ampicillin And Sulbactam Novel Uses: Which Conditions Have a Clinical Trial Featuring Ampicillin And Sulbactam?

41 active trials are currently exploring the potential of Ampicillin and Sulbactam in providing relief for moderate human bites, bacterial infections and intra-abdominal infections.
Condition
Clinical Trials
Trial Phases
Animal bite
0 Actively Recruiting
Bacterial Infections
1 Actively Recruiting
Phase 4
Bacterial Endocarditis
2 Actively Recruiting
Not Applicable
Healthcare-Associated Pneumonia
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Postoperative Wound Infection
3 Actively Recruiting
Not Applicable
Bites, Human
0 Actively Recruiting
severe Bacterial Infections
0 Actively Recruiting
Postoperative Infections
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Catheter Related Infections
3 Actively Recruiting
Not Applicable, Phase 4
Sinusitis
0 Actively Recruiting
Urinary Tract Infection (UTI)
24 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable
moderate Bacterial Infections
0 Actively Recruiting
Intraabdominal Infections
4 Actively Recruiting
Not Applicable, Phase 4
Communicable Diseases
0 Actively Recruiting
Community Acquired Pneumonia (CAP)
1 Actively Recruiting
Not Applicable

Ampicillin And Sulbactam Reviews: What are patients saying about Ampicillin And Sulbactam?

5Patient Review
10/5/2016
Ampicillin And Sulbactam for Abdominal Cavity Lining Infection caused by Enterobacter
This treatment was lifesaving!
4.3Patient Review
7/12/2008
Ampicillin And Sulbactam for Cat Bite Wound
I got this medication as an IV drip and it cleared up my infection very quickly. However, I developed a yeast infection the next day because of the treatment.
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Patient Q&A Section about ampicillin and sulbactam

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the function of ampicillin?

"Ampicillin is an antibiotic used to treat various infections caused by bacteria. These infections include meningitis, infections of the throat, sinuses, lungs, reproductive organs, urinary tract, and gastrointestinal tract."

Answered by AI

What is ampicillin and sulbactam used for?

"Ampicillin and sulbactam combination is used to treat bacterial infections in many different parts of the body. This antibiotic prevents the growth of bacteria by killing them. It belongs to a group of medicines known as penicillins and beta-lactamase inhibitors."

Answered by AI

What is the ampicillin-sulbactam side effects?

"You may experience diarrhea, a rash, swollen or black tongue, vaginal itching or discharge, or pain at the injection site."

Answered by AI

Clinical Trials for Ampicillin And Sulbactam

Have you considered Ampicillin And Sulbactam clinical trials? We made a collection of clinical trials featuring Ampicillin And Sulbactam, we think they might fit your search criteria.
Have you considered Ampicillin And Sulbactam clinical trials? We made a collection of clinical trials featuring Ampicillin And Sulbactam, we think they might fit your search criteria.
Have you considered Ampicillin And Sulbactam clinical trials? We made a collection of clinical trials featuring Ampicillin And Sulbactam, we think they might fit your search criteria.
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