What is Amabelz
NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone, also known as norethindrone, is a synthetic hormone that mimics the effects of the natural hormone progesterone. It is a second-generation hormone which is more potent than progesterone. Norethisterone is commonly used as part of a contraceptive or hormone replacement therapy. It was first created in 1951 and was initially used to treat irregular menstruation and endometriosis, but it wasn’t approved for use as an oral contraceptive until 1962.
Norinylis the brand name
Amabelz Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Norinyl
Norethisterone
1967
347
Effectiveness
How Amabelz Affects PatientsNorethisterone is a type of hormone used to prevent pregnancy or to help with other hormone-related conditions. It works similarly to the hormone progesterone, but is more potent. Norethisterone acts in the pelvic area to change cervical and endometrial function, and also stops the hormones that control ovulation. Taking norethisterone or other combined oral contraceptives can increase the risk of developing breast cancer, so it is important for users to perform regular breast self-exams.
How Amabelz works in the bodyNorethisterone works in several ways. It thickens the cervical mucus to stop sperm from entering the uterus. It also changes the endometrium, making it an unsuitable place for an embryo to attach. Norethisterone also suppresses hormones that help with ovulation, preventing eggs from leaving the ovaries. When used in hormone replacement therapy, norethisterone helps protect against endometrial hyperplasia, which can increase the risk of endometrial cancer. Finally, norethisterone has a low affinity for other steroid receptors, like the androgen receptor and glucocorticoid
When to interrupt dosage
The advisable dosage of Amabelz is based on the diagnosed state, such as Atrophic, Fracture and Hormone Replacement Therapy. The amount of dosage depends on the method of delivery (e.g. Oral or Tablet) featured in the table below.Condition
Dosage
Administration
Oral Contraceptives
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Vasomotor System
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Ovarian Failure
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Birth Control
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Osteoporosis
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Postmenopausal Osteoporosis
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Therapeutic procedure
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Hormone Replacement Therapy
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Endometriosis
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
hypoestrogenism
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Low Testosterone
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
female castration
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Menopause
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Atrophic
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Hormonal Contraception
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Endometriosis
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Fracture
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Estrogen Deprivation Symptoms
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Hot flashes
, 0.014 mg/hour, 1.0 mg, 1.5 mg, 0.5 mg, 0.35 mg, 0.1 mg, 4.8 mg, 30.0 mg, 2.7 mg, 5.0 mg, 0.025 mg/hour, 0.75 mg, 0.4 mg, 0.8 mg, 2.25 mg, 3.0 mg
Oral, Tablet, , Kit; Tablet, chewable - Oral, Kit, Kit; Tablet, Tablet, film coated, Patch, Transdermal, Intramuscular; Oral; Topical, Tablet - Oral, Patch, extended release, Kit - Oral, Kit; Tablet - Oral, Capsule; Kit, Tablet, chewable, Patch, extended release - Transdermal, Kit; Tablet; Tablet, chewable - Oral, Capsule; Kit - Oral, Tablet, film coated - Oral, Kit; Tablet, film coated, Injection, powder, lyophilized, for suspension; Kit; Tablet - Intramuscular; Oral; Topical, Injection, powder, lyophilized, for suspension; Kit; Tablet, Kit; Tablet, chewable, Capsule, Patch - Transdermal, Kit; Tablet; Tablet, chewable, Capsule, liquid filled; Kit, Capsule, liquid filled; Kit - Oral, Capsule - Oral, Kit; Tablet, film coated - Oral, Tablet, chewable - Oral
Warnings
Amabelz has eight recognized contraindications; hence it should not be taken with any of the conditions featured in the table below.Amabelz ContraindicationsCondition
Risk Level
Notes
Malignant Neoplasms
Do Not Combine
Thromboembolism
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Breast Cancer
Do Not Combine
Thrombophilia
Do Not Combine
active liver disease
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Toxoplasma Infections
Common Amabelz Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Amabelz Toxicity & Overdose RiskThe toxic dose of oral contraceptives in mice is 6 g/kg and the toxic dose in women is 42 mg/kg. There have not been any reports of severe outcomes in cases of overdose, including when children consume it. Signs of taking too much oral contraceptive may include severe nausea and/or vomiting.
Amabelz Novel Uses: Which Conditions Have a Clinical Trial Featuring Amabelz?
160 active clinical trials are presently assessing the effectiveness of Amabelz in providing Birth Control, Atrophic and Testosterone Replacement Therapy for Low Testosterone conditions.Condition
Clinical Trials
Trial Phases
Ovarian Failure
3 Actively Recruiting
Not Applicable, Phase 1
Hot flashes
18 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Osteoporosis
43 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3
Menopause
0 Actively Recruiting
Vasomotor System
0 Actively Recruiting
Endometriosis
27 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 1, Phase 4
Low Testosterone
21 Actively Recruiting
Phase 1, Not Applicable, Phase 4, Phase 2
Birth Control
38 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Early Phase 1, Phase 2, Phase 1
Fracture
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Atrophic
4 Actively Recruiting
Phase 4, Phase 2, Not Applicable
Endometriosis
1 Actively Recruiting
Phase 4
hypoestrogenism
1 Actively Recruiting
Phase 4
female castration
0 Actively Recruiting
Postmenopausal Osteoporosis
3 Actively Recruiting
Phase 4, Not Applicable, Phase 3
Estrogen Deprivation Symptoms
0 Actively Recruiting
Hormone Replacement Therapy
0 Actively Recruiting
Oral Contraceptives
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
Amabelz Reviews: What are patients saying about Amabelz?
1Patient Review
5/24/2019 This medicine is terrible and caused me a lot of problems. I bled excessively, had to have surgery to remove ovarian cysts, and last year I developed a lump on my breast.
Patient Q&A Section about amabelz
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Amabelz generic for Activella?
"5 mg'/0.1 mg and1 mg/0.5 mg are therapeutically equivalent to Activella® Tablets0.5 mg/0.1 mg and 1 mg/0.5 mg
Lupin's Amabelz tablets (Estradiol and Norethindrone Acetate Tablets USP, 0.5 mg / 0.1 mg and 1 mg / 0.5 mg) are the AB rated generic equivalent of Amneal Pharmaceuticals' Activella tablets (Estradiol and Norethindrone Acetate Tablets USP, 0.5 mg / 0.1 mg and 1 mg / 0.5 mg). Amabelz tablets 0.5 mg/0.1 mg and1 mg/0.5 mg are therapeutically equivalent to Activella tablets 0.5 mg/0.1 mg and 1 mg/0.5 mg."
Answered by AI
What is Amabelz generic for?
"Amabelz is an oral medication that contains a combination of estradiol and norethindrone acetate. It is indicated for use in women who have a uterus and are experiencing moderate to severe vasomotor symptoms due to menopause. Amabelz can also help prevent postmenopausal osteoporosis and treat moderate to severe symptoms of vulvar and vaginal atrophy."
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What are the side effects of estrogen?
"The following are symptoms of premenstrual syndrome: bloating, breast tenderness or swelling, swelling in other parts of the body, feeling sick, leg cramps, headaches, indigestion, and vaginal bleeding."
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Is Amabelz a HRT?
"It is not known if Amabelz, a drug belonging to a class of drugs called Estrogens/Progestins-HRT, is safe and effective in children."
Answered by AI