Adcirca

Enlarged Prostate, Impotence, Pulmonary Arterial Hypertension
Treatment
5 FDA approvals
20 Active Studies for Adcirca

What is Adcirca

TadalafilThe Generic name of this drug
Treatment SummaryTadalafil is a medicine that helps to treat erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and enlargement of the prostate. It was approved by the FDA in 2003 for ED and in 2009 for PAH. It works differently than other PDE5 inhibitors like sildenafil, as it has a longer lasting effect and is more selective for PDE5, making it a better treatment option for long-term daily use in PAH.
Cialisis the brand name
image of different drug pills on a surface
Adcirca Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cialis
Tadalafil
2003
295

Approved as Treatment by the FDA

Tadalafil, commonly known as Cialis, is approved by the FDA for 5 uses including Erectile dysfunction and Pulmonary Arterial Hypertension (PAH) .
Erectile dysfunction
Helps manage Erectile Dysfunction
Pulmonary Arterial Hypertension (PAH)
Helps manage Pulmonary Arterial Hypertension (PAH)
Impotence
Helps manage Erectile Dysfunction
Pulmonary Arterial Hypertension
Helps manage Pulmonary Arterial Hypertension (PAH)
Enlarged Prostate

Effectiveness

How Adcirca Affects PatientsTadalafil helps treat ED by increasing blood flow to the penis, allowing an erection to occur. It also decreases blood pressure in the lungs in cases of pulmonary arterial hypertension. In cases of BPH, tadalafil may reduce the size of the prostate and relieve its symptoms. This drug has less of a chance of causing visual side effects than other similar drugs.
How Adcirca works in the bodyTadalafil is a medicine that helps relax the muscles in the penis, lungs, and prostate. In the penis, this allows more blood to enter, resulting in an erection. In the lungs, it can reduce high blood pressure and improve oxygen flow. In the prostate, it helps reduce inflammation and tissue growth. Tadalafil also has less of a chance to cause side effects related to vision than other similar medicines because it binds to a different enzyme in the eye.

When to interrupt dosage

The endorsed dosage of Adcirca is contingent upon the diagnosed condition, like Impotence, Pulmonary Arterial Hypertension and Enlarged Prostate. The amount of dosage fluctuates as per the delivery approach (e.g. Tablet, film coated - Oral or Tablet) identified in the table beneath.
Condition
Dosage
Administration
Enlarged Prostate
, 10.0 mg, 20.0 mg, 5.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Capsule - Oral, Capsule
Pulmonary Arterial Hypertension
, 10.0 mg, 20.0 mg, 5.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Capsule - Oral, Capsule
Impotence
, 10.0 mg, 20.0 mg, 5.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated, Capsule - Oral, Capsule

Warnings

Adcirca has two contraindications and should be avoided if you are encountering any of the conditions given in the following table.Adcirca Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Adcirca.
Common Adcirca Drug Interactions
Drug Name
Risk Level
Description
Alprostadil
Major
The risk or severity of hypotension and priapism can be increased when Tadalafil is combined with Alprostadil.
Amifostine
Major
Tadalafil may increase the hypotensive activities of Amifostine.
Amyl Nitrite
Major
The risk or severity of hypotension can be increased when Tadalafil is combined with Amyl Nitrite.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Tadalafil.
Avanafil
Major
The risk or severity of adverse effects can be increased when Tadalafil is combined with Avanafil.
Adcirca Toxicity & Overdose RiskAn overdose of tadalafil may lead to the same side effects as normal doses, such as headache, indigestion, back pain, muscle aches, inflammation of the nose and throat, and dizziness. Standard supportive care is recommended and hemodialysis is not likely to be effective in removing the drug from the bloodstream.
image of a doctor in a lab doing drug, clinical research

Adcirca Novel Uses: Which Conditions Have a Clinical Trial Featuring Adcirca?

95 active clinical trials are exploring the potential of Adcirca to alleviate Impotence, Pulmonary Arterial Hypertension and Enlarged Prostate.
Condition
Clinical Trials
Trial Phases
Pulmonary Arterial Hypertension
4 Actively Recruiting
Phase 1, Not Applicable, Phase 2
Enlarged Prostate
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Impotence
18 Actively Recruiting
Not Applicable, Phase 4, Early Phase 1, Phase 3, Phase 1

Adcirca Reviews: What are patients saying about Adcirca?

5Patient Review
10/23/2015
Adcirca for Pulmonary Arterial Hypertension
My daughter, who has been living with pulmonary hypertension since she was six, just switched from Revatio to Adcirca this month. She says she's already feeling better; less winded and able to exercise more. Let's hope the good results keep coming in!
5Patient Review
5/9/2011
Adcirca for Inability to have an Erection
The price tag on this one is pretty hefty, but fortunately my insurance company was willing to work with me. As for the side effects, heartburn was the big one for me. It didn't matter what I ate or drank, it would always give me indigestion. The doctor advised that I take Zantac 150mg twice a day to combat it.
4.7Patient Review
5/13/2010
Adcirca for Inability to have an Erection
4.3Patient Review
1/22/2013
Adcirca for Increased Pressure of Pulmonary Circulation
Cialis is great stuff. I was able to achieve and maintain erections for hours on end. My only issue was that my insurance companies didn't want to cover it because my doctor wouldn't lie and say it was for heart problems or blood pressure issues.
4Patient Review
11/22/2017
Adcirca for Pulmonary Arterial Hypertension
I didn't experience any benefits from this treatment. In fact, it seems to have messed with my hormones and brought back my periods after 15 years of being off them. Now that I've stopped taking the medication, my periods have stopped again.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about adcirca

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Adcirca prescribed for?

"Adcirca belongs to a class of medicines known as Phosphodiesterase Type 5 Inhibitors.

Adcirca is a medication used to manage the symptoms of erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia. It works by inhibiting phosphodiesterase type 5 and can be used in conjunction with other medications."

Answered by AI

Is Cialis the same as Adcirca?

"Both Cialis and Adcirca (tadalafil) contain the same active ingredient, tadalafil. However, Cialis is approved by the FDA to treat erectile dysfunction (ED) and enlarged prostate (BPH), whereas Adcirca (tadalafil) is approved to treat pulmonary arterial hypertension (PAH)."

Answered by AI

What are the side effects of Adcirca?

"You may experience some side effects such as dizziness, lightheadedness, headache, muscle pain, flushing, nausea, stuffy nose, or stomach upset. If you notice any of these effects lasting or getting worse, please tell your doctor or pharmacist. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position."

Answered by AI

Can I take Adcirca instead of Cialis?

"ADCIRCA is the same as CIALIS and is used to treat male erectile dysfunction and the signs and symptoms of benign prostatic hyperplasia. You should not take both ADCIRCA and CIALIS and you should not take ADCIRCA with other medicines or treatments for erectile dysfunction."

Answered by AI

Clinical Trials for Adcirca

Have you considered Adcirca clinical trials? We made a collection of clinical trials featuring Adcirca, we think they might fit your search criteria.
Have you considered Adcirca clinical trials? We made a collection of clinical trials featuring Adcirca, we think they might fit your search criteria.
Have you considered Adcirca clinical trials? We made a collection of clinical trials featuring Adcirca, we think they might fit your search criteria.
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