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Robotics

Sensory-Motor Rehabilitation for Stroke

N/A

Recruiting

Led By Li-Qun Zhang, Ph.D.

Research Sponsored by University of Maryland, Baltimore

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 18-80

Ankle impairments

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at the beginning and end of 3-week training, and 1 month after the treatment ends

Awards & highlights

Study Summary

This trial will test whether an intensive motor-sensory rehabilitation using a wearable robot can help patients with acute stroke recover sensorimotor function, reduce ankle impairments, and improve balance and gait.

Who is the study for?

This trial is for stroke survivors aged 18-80 with ankle impairments and hemiplegia or hemiparesis. It's suitable for those who've had their first unilateral acute stroke, either hemorrhagic or ischemic, from 24 hours to a year post-stroke. Excluded are individuals with mild/no impairment, severe cardiovascular issues, cognitive impairments preventing instruction following, unstable medical conditions, leg ulcers/wounds below the knee, or severe leg pain.Check my eligibility

What is being tested?

The study tests an intensive motor-sensory rehabilitation using a wearable robot on patients after a stroke. The goal is to aid sensorimotor recovery and improve balance and walking by reducing ankle impairments. Participants will be randomly assigned to either the Study group receiving therapy or Control group.See study design

What are the potential side effects?

While not explicitly stated in this summary, potential side effects may include muscle soreness due to stretching and movement exercises as well as skin irritation from wearing the rehabilitation robot.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 18 and 80 years old.

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I have issues with my ankle.

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I have weakness or paralysis on one side of my body.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at the beginning and end of 3-week training, and 1 month after the treatment ends

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at the beginning and end of 3-week training, and 1 month after the treatment ends

This trial's timeline: 3 weeks for screening, Varies for treatment, and at the beginning and end of 3-week training, and 1 month after the treatment ends for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes of Fugl-Meyer Lower Extremity (FMLE)

Secondary outcome measures

Changes of 10 meter Walk Test

Changes of Berg Balance Scale

Changes of Modified Ashworth Scale (MAS)

+4 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Study groupExperimental Treatment1 Intervention

Subjects in the Study group will receive stretching and active movement training with robotic guidance and intelligent control

Group II: Control groupExperimental Treatment1 Intervention

Subjects in the Control group will receive stretching and active movement training without robotic guidance.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Northwestern UniversityOTHER

1,589 Previous Clinical Trials

916,986 Total Patients Enrolled

30 Trials studying Stroke

25,065 Patients Enrolled for Stroke

Northwestern Memorial HospitalOTHER

40 Previous Clinical Trials

16,576 Total Patients Enrolled

University of Maryland, BaltimoreLead Sponsor

688 Previous Clinical Trials

374,516 Total Patients Enrolled

10 Trials studying Stroke

1,331 Patients Enrolled for Stroke

Media Library

Stretching and Active Movement Training (Robotics) Clinical Trial Eligibility Overview. Trial Name: NCT02369770 — N/A

Stretching and Active Movement Training (Robotics) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02369770 — N/A

Stroke Research Study Groups: Study group, Control group

Stroke Clinical Trial 2023: Stretching and Active Movement Training Highlights & Side Effects. Trial Name: NCT02369770 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to join this research project?

"This clinical trial seeks to enrol 140 stroke sufferers aged 18-80. Additionally, potential participants must have had a unilateral acute stroke within 24 hours of hospital admission and up until one year post-stroke; they must also display hemiplegia or hemiparesis as well as impairment in their ankles."

Answered by AI

Does this research accept older volunteers?

"This trial necessitates that participants are aged 18 to 80. If a patient is under the age of consent, 37 studies may be available while 1007 trials exist for those over 65."

Answered by AI

Is enrollment into this research endeavor still open?

"Clinicaltrials.gov affirms that this medical trial is currently attempting to enrol participants and was first posted on April 26th 2019, with the last alteration taking place on March 17th 2022."

Answered by AI

How many individuals are being included in this research project?

"Affirmative. As per the clinicaltrials.gov website, this medical trial is presently recruiting patients who meet its inclusion criteria and have been approved by their physician. It was initially published on April 26th 2019, with recent changes made on March 17th 2022, and aims to enrol 140 participants from a sole location."

Answered by AI

Recent research and studies

Neural RegenerationJournal

Chapter 21 Reorganization of Neocortical Representations After Brain Injury: A Neurophysiological Model of the Bases of Recovery from Stroke

Jenkins, William M., and Michael M. Merzenich. 1987. “Chapter 21 Reorganization of Neocortical Representations After Brain Injury: A Neurophysiological Model of the Bases of Recovery from Stroke”. Neural Regeneration. Elsevier. doi:10.1016/s0079-6123(08)61829-4.

Nature Reviews NeuroscienceJournal

Plasticity During Stroke Recovery: From Synapse to Behaviour

Murphy, Timothy H., and Dale Corbett. 2009. “Plasticity During Stroke Recovery: From Synapse to Behaviour”. Nature Reviews Neuroscience. Springer Science and Business Media LLC. doi:10.1038/nrn2735.

Journal of NeurophysiologyJournal

Plasticity of Primary Somatosensory Cortex Paralleling Sensorimotor Skill Recovery from Stroke in Adult Monkeys

Xerri, Christian, Michael M. Merzenich, Bret E. Peterson, and William Jenkins. 1998. “Plasticity of Primary Somatosensory Cortex Paralleling Sensorimotor Skill Recovery from Stroke in Adult Monkeys”. Journal of Neurophysiology. American Physiological Society. doi:10.1152/jn.1998.79.4.2119.

Journal of NeurologyJournal