Spin for Aging

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
AgingSpin - Other
Eligibility
65 - 80
All Sexes
What conditions do you have?
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Study Summary

This trial will study how a 12-week aerobic exercise intervention affects brain health measures in older Veterans. The hypothesis is that the intervention will increase perfusion and improve CVR in brain regions susceptible to age-related decline.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: At the Pre-intervention assessment and 12-weeks following at the Post intervention assessment

At the Pre-intervention assessment and 12-weeks following at the Post intervention assessment
Arterial Spin Labeling (ASL) to Measure Cerebral Blood Flow Change
Cerebrovascular reactivity (CVR) using a hypercapnic CO2 response test change

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

Control
1 of 2
Spin
1 of 2

Active Control

Experimental Treatment

80 Total Participants · 2 Treatment Groups

Primary Treatment: Spin · No Placebo Group · Phase 2 & 3

Spin
Other
Experimental Group · 1 Intervention: Spin · Intervention Types: Other
Control
Other
ActiveComparator Group · 1 Intervention: Spin · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: at the pre-intervention assessment and 12-weeks following at the post intervention assessment

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,485 Previous Clinical Trials
2,742,139 Total Patients Enrolled
22 Trials studying Aging
2,647 Patients Enrolled for Aging
Joe R. Nocera, PhDPrincipal InvestigatorAtlanta VA Medical and Rehab Center, Decatur, GA
3 Previous Clinical Trials
276 Total Patients Enrolled
1 Trials studying Aging
48 Patients Enrolled for Aging

Eligibility Criteria

Age 65 - 80 · All Participants · 10 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a chronic heart condition.
You have kidney disease.
You have a minimum of 26 on the MoCA.