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Dexrazoxane for Preventing Heart Failure (PHOENIX1 Trial)
PHOENIX1 Trial Summary
This trial will test whether Dexrazoxane can prevent Doxorubicin-related heart damage.
PHOENIX1 Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPHOENIX1 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 2 trial • 73 Patients • NCT02584309PHOENIX1 Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- I have a history of kidney disease.I do not have any current illnesses.I am a woman.I have a history of heart disease.I am between 18 and 65 years old.I am currently ill.I am a woman.I do not have any current illnesses.
- Group 1: Dexrazoxane 100mg/m2
- Group 2: Dexrazoxane 200mg/m2
- Group 3: Dexrazoxane 300mg/m2
- Group 4: Dexrazoxane 500mg/m2
- Group 5: Dexrazoxane 400mg/m2
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there still openings for involvement in this research project?
"Affirmative. As per the data on clinicaltrials.gov, this medical experiment which was initially posted on June 1st 2021 is actively accepting participants. A total of 25 volunteers need to be recruited from one clinic site."
Does this experimental research accept participants over the age of thirty?
"As outlined in the eligibilty criteria, this trial is open to patients aged between 18 and 65."
Has Dexrazoxane been employed in any other scientific experiments?
"Currently, 14 clinical trials are testing Dexrazoxane's potential efficacy and safety. Of those studies, 6 have progressed to the final phase of research. Sioux Falls is hosting most of these experiments; however, 1074 other medical centres throughout America are also running similar investigations for this drug."
To whom is this clinical research open?
"This clinical trial seeks 25 individuals with heart failure aged from 18 to 65 years old. Applicants must meet the following criteria: no concurrent illness, female sex, age range of 18-65, not pregnant and lactating."
To what extent has the participant cap been reached for this research endeavor?
"Affirmative. Clinicaltrials.gov's information clearly states that this experiment is presently in need of participants, initially posted on June 1st 2021 and recently updated on March 15th 2022. 25 subjects are required to be enrolled at a single medical centre."
To what extent might Dexrazoxane pose a risk to those undergoing treatment?
"Due to the limited amount of data available concerning its efficacy and safety, dexrazoxane has been evaluated as a 1 on our risk assessment scale."
To which conditions does Dexrazoxane typically lend therapeutic support?
"Dexrazoxane is typically used to manage doxorubicin toxicity; however, it can be useful for treating anthracycline-induced chemotherapy side effects, malignant neoplasms, and drug extravasation."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Why did patients apply to this trial?
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