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Glucose Load Test for Studying Fat Tissue Blood Flow in Aging
N/A
Recruiting
Led By Kelli Lytle, PhD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Within the ages of 18-35 years or 65-80 years at time of study visit
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, pre-intervention fasting and immediately following 75 gm oral glucose load
Awards & highlights
Study Summary
This trial will study how blood flow in fat tissue changes between younger and older adults, and what affects this. Participants will have tests and biopsies.
Who is the study for?
This trial is for healthy adults aged 18-35 or 65-80 with a BMI of 20-25. It's not for those with heart disease, diabetes, high blood pressure, on certain meds affecting fat metabolism (like statins), pregnant/nursing women, smokers, or anyone unable to consent.Check my eligibility
What is being tested?
The study investigates how blood flow in fatty tissue differs between younger and older adults by using the xenon washout technique after participants drink a sugary solution. It also looks at molecular changes related to this blood flow.See study design
What are the potential side effects?
Potential side effects may include discomfort from the adipose tissue biopsy and reactions to drinking the glucose solution such as nausea or bloating.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am either 18-35 or 65-80 years old.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline, pre-intervention fasting and immediately following 75 gm oral glucose load
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, pre-intervention fasting and immediately following 75 gm oral glucose load
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Adipose tissue blood flow
Secondary outcome measures
Genomic alterations
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Older AdultsExperimental Treatment1 Intervention
Group II: Younger AdultsActive Control1 Intervention
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Who is running the clinical trial?
Mayo ClinicLead Sponsor
3,216 Previous Clinical Trials
3,767,464 Total Patients Enrolled
13 Trials studying Aging
4,680 Patients Enrolled for Aging
National Center for Advancing Translational Sciences (NCATS)NIH
322 Previous Clinical Trials
401,739 Total Patients Enrolled
3 Trials studying Aging
74 Patients Enrolled for Aging
Kelli Lytle, PhDPrincipal InvestigatorMayo Clinic
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any remaining vacancies for participants in this trial?
"According to the latest information on clinicaltrials.gov, this experiment is no longer recruiting participants as of October 19th 2023; when it was initially posted on November 1st 2023. Nevertheless, there are still 1081 other trials actively enrolling at present."
Answered by AI
Does the recruitment criteria for this clinical trial encompass those aged 75 or above?
"The eligibility requirements for this medical trial specifies that applicants must be between 18 and 80 years old."
Answered by AI
Who meets the eligibility requirements for participating in this research study?
"To qualify for this medical trial, applicants should be in good health and within the ages of 18 to 80. At maximum, 24 individuals will gain access to this study."
Answered by AI
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