Behavioral Intervention for Chronic Pain and Depression in Older Veterans
(MOTIVATE_IIR Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify whether you need to stop taking your current medications. However, since it focuses on a non-drug program, you might be able to continue your medications. It's best to discuss this with the trial coordinators.
What data supports the effectiveness of the treatment Behavioral Intervention Group (MOTIVATE) for chronic pain and depression in older veterans?
Research shows that cognitive behavioral therapy (CBT), a key component of the MOTIVATE treatment, is effective in reducing pain and depression in veterans. Studies have demonstrated significant improvements in pain intensity, depression, and quality of life among veterans receiving CBT for chronic pain.12345
Is the behavioral intervention for chronic pain and depression in older veterans safe?
The studies suggest that behavioral interventions, including those using motivational interviewing and cognitive behavioral therapy, are generally safe and acceptable for individuals with chronic pain and depression. Participants reported positive experiences and no significant safety concerns were noted in the trials.36789
How is the MOTIVATE treatment different from other treatments for chronic pain and depression in older veterans?
The MOTIVATE treatment is unique because it combines behavioral interventions specifically tailored for older veterans with chronic pain and depression, focusing on brief, effective therapy sessions that can be as impactful as longer treatments. This approach is designed to improve pain-related thinking and reduce disability and distress, offering a practical and efficient alternative to more time-intensive therapies.2341011
What is the purpose of this trial?
The proposed study seeks to evaluate effectiveness, implementation processes, and cost of MOTIVATE among older Veterans with chronic musculoskeletal (MSK) pain and comorbid depressive symptoms.
Research Team
Una E. Makris, MD MSc
Principal Investigator
VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX
Eligibility Criteria
This trial is for older Veterans aged 60+ who speak English, have chronic musculoskeletal pain and depressive symptoms. They must be able to do home-based activities, score 10+ on the PHQ-9 depression scale, experience pain most days with an intensity of 4+/10 and interference level of 5+ on PEG-3. Exclusions include severe cognitive impairment, recent hospitalization that affects physical activity, suicidal intent or uncontrolled psychotic disorders.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive the MOTIVATE intervention, a remotely delivered behavioral intervention, over 8 sessions via telephone
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments at baseline, mid, end, and 6 months
Waitlist Control
Participants in the waitlist control group continue with usual care and are offered the intervention after completing the end outcomes assessment
Treatment Details
Interventions
- Behavioral Intervention Group (MOTIVATE)
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor
Dallas VA Medical Center
Collaborator
Michael E. DeBakey VA Medical Center
Collaborator