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Radiation Therapy
Radiation Therapy for Metastatic Cancer
N/A
Recruiting
Led By Atif Khan, MD
Research Sponsored by Memorial Sloan Kettering Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks from baseline
Awards & highlights
Study Summary
This trial compares two types of radiation therapy to see which is more effective and how it affects the tumor's ability to be attacked by the immune system. #LRTvsSBRT
Who is the study for?
This trial is for adults with advanced solid tumors needing palliative radiation, who have at least one other site of metastasis suitable for radiation. They must be in good physical condition (ECOG 0 or 1) and understand the study's risks. It's not for those previously radiated at the same sites, with uncontrolled conditions like infections or diabetes, on steroids, pregnant/breastfeeding, having a second active cancer, or unable to follow study procedures.Check my eligibility
What is being tested?
The trial compares two types of radiation therapy: Lattice Radiation Therapy (LRT) and standard Stereotactic Body Radiation Therapy (SBRT). The goal is to see which method is more effective and how they influence immune cells' ability to attack tumor cells.See study design
What are the potential side effects?
Radiation therapy side effects can include skin reactions where treated, fatigue, nausea, pain at treatment site. Long-term effects might involve damage to nearby organs/tissues depending on where the radiation targets.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 12 weeks from baseline
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks from baseline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Overall Response Rate (ORR)
Trial Design
1Treatment groups
Experimental Treatment
Group I: Participants with metastatic solid tumorsExperimental Treatment2 Interventions
Participants will have metastatic solid tumors and at least two sites of measurable extra-cranial disease
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Stereotactic body radiotherapy
2014
Completed Phase 4
~370
Find a Location
Who is running the clinical trial?
Memorial Sloan Kettering Cancer CenterLead Sponsor
1,934 Previous Clinical Trials
588,784 Total Patients Enrolled
203 Trials studying Breast Cancer
81,137 Patients Enrolled for Breast Cancer
Varian Medical SystemsIndustry Sponsor
58 Previous Clinical Trials
3,713 Total Patients Enrolled
2 Trials studying Breast Cancer
322 Patients Enrolled for Breast Cancer
Atif Khan, MDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center
3 Previous Clinical Trials
125 Total Patients Enrolled
3 Trials studying Breast Cancer
125 Patients Enrolled for Breast Cancer
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have an advanced cancer that needs radiation therapy for symptom relief.I understand the study's purpose and risks and can give informed consent.I am willing and able to follow all study requirements.I have another cancer that has spread.I am currently taking corticosteroids.I am receiving other cancer treatments while undergoing radiation.I have had radiation therapy on the cancer areas being considered for treatment.I have cancer that has spread to at least one other part of my body outside the brain.I am 18 years old or older.I am fully active or can carry out light work.I do not have uncontrolled infections, diabetes, or connective tissue diseases.
Research Study Groups:
This trial has the following groups:- Group 1: Participants with metastatic solid tumors
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is the cap on the number of participants in this trial?
"Affirmative, according to clinicaltrials.gov this medical study initiated on April 19th 2023 and is currently recruiting volunteers. Seven different sites are looking for a total of 26 participants."
Answered by AI
How many sites are participating in the implementation of this clinical trial?
"Seven different medical centres are taking part in this study, with Memorial Sloan Kettering Monmouth (Limited Protocol Activities) situated in Middletown, Memorial Sloan Kettering Bergen (Limited protocol activities) located in Montvale and the Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities) based out of Commack. The other four sites can be found through additional research."
Answered by AI
Are there any remaining vacancies for this research program?
"Affirmative, clinicaltrials.gov records demonstrate that this experiment is actively recruiting participants. This research was first posted on April 19th 2023 and has been recently revised on the following day. 26 individuals are being sought from 7 different sites across the US."
Answered by AI
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