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Neuromodulation

LIFU for Autonomic Nervous System Disorders

N/A

Waitlist Available

Research Sponsored by Virginia Polytechnic Institute and State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 1 month

Awards & highlights

Study Summary

This trial studies how LIFU affects the autonomic nervous system using 3 tests. Physiological recordings will be taken before and after the treatment.

Who is the study for?

This trial is for individuals with autonomic nervous system disorders who don't have claustrophobia, metal implants incompatible with MRI or CT scans, active CNS-affecting medical conditions, a history of significant head injury, substance dependence, or cardiac disease.Check my eligibility

What is being tested?

The study tests if Low Intensity Focused Ultrasound (LIFU) targeting specific brain areas affects the body's automatic functions. Participants undergo cold pressor task, valsalva maneuver and deep breathing tasks before and after LIFU to measure changes.See study design

What are the potential side effects?

Potential side effects are not explicitly listed but may include discomfort from the ultrasound procedure or reactions to being in an MRI/CT scan environment due to noise and confinement.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 1 month

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 1 month

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Sympathetic tone response - Blood Pressure (BP)

Sympathetic tone response - Electrodermal Response (EDR)

Sympathetic tone response - Electroencephalography (EEG)

+2 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Repeat measure LIFU and ShamExperimental Treatment1 Intervention

LIFU or Sham applied in repeat sessions to varying brain regions (dAI and dACC).

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor

141 Previous Clinical Trials

27,686 Total Patients Enrolled

Media Library

Low-intensity focused ultrasound neuromodulation (Neuromodulation) Clinical Trial Eligibility Overview. Trial Name: NCT05834829 — N/A

Autonomic Nervous System Disorders Research Study Groups: Repeat measure LIFU and Sham

Autonomic Nervous System Disorders Clinical Trial 2023: Low-intensity focused ultrasound neuromodulation Highlights & Side Effects. Trial Name: NCT05834829 — N/A

Low-intensity focused ultrasound neuromodulation (Neuromodulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05834829 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to partake in this research endeavor?

"Those who wish to join this clinical trial must have an autonomic nervous system disorder and be between 18-39 years old. The program has a capacity of 80 patients."

Answered by AI

Is there an ongoing call for volunteers for this trial?

"As per clinicaltrials.gov, this study is not currently recruiting patients. The trial was first advertised on April 30th 2023 and last revised on April 17th 2023. However, there are 27 other trials that are presently welcoming participants to join their research programs."

Answered by AI