PBM Therapy for Canker Sores
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests two treatments for canker sores in children: laser photobiomodulation (PBM) therapy and Magic Mouthwash. It aims to determine which treatment better eases pain, speeds healing, and improves comfort. Children with canker sores identified during a dental visit, who have not tried PBM before, and whose guardians speak English or Spanish, may be suitable candidates. The goal is to discover if laser treatment significantly improves healing and pain relief compared to standard care. As a Phase 4 trial, this research explores how these FDA-approved treatments can benefit more patients.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What is the safety track record for these treatments?
Research has shown that PBM (photobiomodulation) therapy is generally safe for oral health treatments. Studies have found that this light therapy, which does not use heat, can reduce pain and swelling without causing major side effects. Notably, no reports of serious problems have emerged in patients using PBM for oral issues. Patients usually tolerate it well, experiencing little to no discomfort during or after treatment. This makes PBM an attractive option for managing pain in conditions like canker sores.12345
Why are researchers enthusiastic about this study treatment?
Photobiomodulation (PBM) therapy is unique because it uses light to stimulate healing in canker sores, unlike standard treatments that typically involve topical steroids or antiseptic mouthwashes. This non-invasive approach targets the source of pain and inflammation directly, potentially speeding up recovery without the side effects associated with medication. Researchers are excited about PBM therapy because it offers a novel mechanism of action by enhancing cellular repair and reducing discomfort more rapidly than conventional options. Plus, it could provide a new avenue for those who don't respond well to traditional treatments.
What evidence suggests that PBM Therapy is effective for canker sores?
Studies have shown that light therapy, known as photobiomodulation (PBM), effectively reduces pain from mouth sores like canker sores. One study found that 90% of participants experienced pain relief by the third day of PBM treatment. Another study demonstrated that a specific type of PBM laser provided immediate pain relief and accelerated sore healing. In this trial, participants will receive either PBM therapy or standard care. These findings suggest that PBM therapy could be a promising option for managing pain and speeding up the healing of canker sores in children.46789
Who Is on the Research Team?
Brett Chiquet, DDS, PhD
Principal Investigator
The University of Texas Health Science Center, Houston
Are You a Good Fit for This Trial?
This trial is for pediatric dental patients who are experiencing pain from canker sores. The study aims to include those who could benefit from treatments aimed at reducing discomfort and speeding up healing.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either laser photobiomodulation or 'Magic Mouthwash' for treatment of pain in aphthous ulcers
Follow-up
Participants are monitored for changes in pain levels and quality of life after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Maalox plus Benadryl
- PBM Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Health Science Center, Houston
Lead Sponsor