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What is Ziagen
AbacavirThe Generic name of this drug
Treatment SummaryAbacavir (ABC) is a medication used to treat HIV and AIDS. It works by blocking the action of the virus in the body. Abacavir is a synthetic carbocyclic nucleoside that is made up of two different parts: abacavir sulfate and its free base, abacavir.
Ziagenis the brand name
Ziagen Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ziagen
Abacavir
1998
64
Approved as Treatment by the FDA
Abacavir, also called Ziagen, is approved by the FDA for 1 uses like HIV .HIV
Used to treat Human Immunodeficiency Virus Type 1 (HIV-1) Infection in combination with Dolutegravir
Effectiveness
How Ziagen Affects PatientsAbacavir is a medication used to treat HIV-1. It is converted into active chemicals which prevent the virus from making copies of itself. This drug is effective against HIV-1, and has been shown to be most effective when taken with other HIV medications, such as zidovudine, nevirapine, or amprenavir. It has also been found to work well when taken with didanosine, emtricitabine, lamivudine, stavudine, tenofovir, and zalcitabine.
How Ziagen works in the bodyAbacavir is a drug used to fight HIV. It works by blocking an enzyme called HIV-1 reverse transcriptase in infected cells. This enzyme is responsible for making a copy of the virus, and when it's blocked, the virus cannot reproduce. Abacavir is converted into an active form in the body, which stops the enzyme from making new copies of the virus.
When to interrupt dosage
The suggested dose of Ziagen is determined by the diagnosed condition. The amount of dosage fluctuates based on the method of delivery (e.g. Oral or Tablet, film coated - Oral) featured in the following table.Condition
Dosage
Administration
HIV
, 300.0 mg, 600.0 mg, 20.0 mg/mL, 60.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Warnings
Ziagen has three contraindications and should not be taken in combination with the circumstances listed in the below table.Ziagen ContraindicationsCondition
Risk Level
Notes
HLA-B Antigens
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
Moderate Hepatic Impairment
Do Not Combine
Common Ziagen Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
Abacavir may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Abacavir may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Abacavir may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Allylestrenol
Minor
Abacavir may decrease the excretion rate of Allylestrenol which could result in a higher serum level.
Almasilate
Minor
Abacavir may decrease the excretion rate of Almasilate which could result in a higher serum level.
Ziagen Toxicity & Overdose RiskStudies have shown some signs of heart damage in rats and mice. The most commonly reported side effects in adults are nausea, headache, fatigue, vomiting, and sleeping problems. Abacavir can cause serious allergic reactions in people that carry the HLA-B*57:01 gene. Patients should get tested for this gene before taking abacavir as recommended by the FDA.
Ziagen Novel Uses: Which Conditions Have a Clinical Trial Featuring Ziagen?
Presently, 43 clinical trials are assessing the efficacy of Ziagen in treating HIV (Human Immunodeficiency Virus).Condition
Clinical Trials
Trial Phases
HIV
42 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1
Ziagen Reviews: What are patients saying about Ziagen?
3.7Patient Review
7/15/2008 Being undetectable is wonderful, but I have been having difficulty breathing for a few years now. It's gotten to the point where it really interferes with my quality of life. My doctor doesn't think it warrants taking me off the medication, so I guess I'll just have to deal with it.
Patient Q&A Section about ziagen
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic name for Ziagen?
"Abacavir is a drug used to treat HIV infection. It is part of a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). It is not a cure for HIV infection."
Answered by AI
How much is Ziagen?
"The average retail price of Ziagen is $698.47 per 60, 300MG Tablet, but when you use your SingleCare copay card, you will only have to pay $52.64."
Answered by AI
What is Ziagen used for?
"The drug abacavir, sold under the brand name Ziagen, is approved by the U.S. Food and Drug Administration for the treatment of HIV infection in adults, children, and infants. It must be used in combination with other HIV medications."
Answered by AI
How do you take Ziagen?
"- Jul 30, 2022
The recommended dose for adults and older children is 600 mg (two tablets) daily, either as a single dose or divided into two doses taken morning and evening. Your doctor will tell you how you should take the tablets."
Answered by AI