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What is Zerviate
CetirizineThe Generic name of this drug
Treatment SummaryCetirizine, also known as Zyrtec, is a medication used to treat allergy symptoms such as sneezing, coughing, nasal congestion, and hives. It is often prescribed for a condition called allergic rhinitis, which affects 15-30% of people in the United States. Allergic rhinitis can cause difficulty with day-to-day activities, missed or unproductive days at work or school, and problems with sleep. Cetirizine is a second-generation H1 antihistamine (SGAH), which means it can block the H1 receptor in the body without causing sed
12 Hour Allergy Dis the brand name
Zerviate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
12 Hour Allergy D
Cetirizine
1988
805
Approved as Treatment by the FDA
Cetirizine, otherwise called 12 Hour Allergy D, is approved by the FDA for 10 uses including Allergy to Animal Dander and Hay Fever .Allergy to Animal Dander
Hay Fever
Grass Allergy
House Dust Mite Allergy
Perennial Allergic Rhinitis (PAR)
Allergy to Mold
Allergy to Tree Pollen
Used to treat Allergy to Tree Pollen in combination with Pseudoephedrine
Chronic Urticaria
Ragweed Allergy
Respiratory Allergy
Used to treat Respiratory Allergy in combination with Pseudoephedrine
Effectiveness
How Zerviate Affects PatientsCetirizine is a drug used to treat a variety of conditions, including chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis. It has been proven to be effective in treating respiratory allergies, and may also have anti-inflammatory properties that can help with asthma management. Cetirizine works quickly, reducing skin reactions such as wheals and flareups within 20 minutes of taking a single dose. It also helps reduce the time and amount of topical anti-inflammatory formulas needed to treat atopic dermat
How Zerviate works in the bodyCetirizine is a medicine used to treat allergies. It works by blocking the action of a chemical called histamine in your body. Histamine is responsible for many allergy symptoms. Cetirizine has been tested and has shown to be effective in treating allergies and has few side effects. It does not appear to affect other types of receptors in the body, and it does not appear to pass into the brain.
When to interrupt dosage
The prescribed amount of Zerviate is contingent upon the diagnosed condition, including Chronic Idiopathic Urticaria, Allergy to Tree Pollen and Allergy; Dander. The magnitude of dosage deviates, in accordance with the administration technique (e.g. Oral or Syrup) featured in the table below.Condition
Dosage
Administration
Allergy to Tree Pollen
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Influenza
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
House Dust Mite Allergy
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Chronic Urticaria
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Ragweed Allergy
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Allergy to Mold
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Grass Allergy
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Allergy to Animal Dander
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Hay Fever
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Perennial Allergic Rhinitis (PAR)
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Respiratory Allergy
, 5.0 mg/mL, 10.0 mg, 5.0 mg, 1.0 mg/mL, 1.0 mg, 20.0 mg, 2.4 mg/mL, 10.0 mg/mL, 2.5 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated, Tablet, chewable, Tablet, chewable - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Ophthalmic, Suspension - Oral, Suspension, Solution / drops, Solution / drops - Ophthalmic, Injection - Intravenous, Intravenous, Injection
Warnings
Zerviate has two contraindications. It should not be taken together with any of the conditions stipulated in the subsequent table.Zerviate ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Cetirizine may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Cetirizine may interact with Pulse Frequency
Common Zerviate Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Hydroxyzine.
Mobocertinib
Major
The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Mobocertinib.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Cetirizine is combined with Oliceridine.
Zerviate Toxicity & Overdose RiskThe toxic dose of cetirizine in rats is 365mg/kg and in mice is 138mg/kg. In a two-year study, cetirizine was not associated with any cancer-causing effects in rats and mice given dietary doses up to 20mg/kg and 16mg/kg, respectively. Cetirizine was not found to be harmful to fertility in mice given a dose of 64mg/kg. It is categorized as pregnancy category B, meaning it has not been proven to be harmful for pregnant women, but should only be used if necessary. Cetirizine has been
Zerviate Novel Uses: Which Conditions Have a Clinical Trial Featuring Zerviate?
38 active clinical trials are being conducted to assess the efficacy of Zerviate in treating Chronic Idiopathic Urticaria, Mold Allergy and Grass Allergy.Condition
Clinical Trials
Trial Phases
Influenza
32 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1
Allergy to Animal Dander
0 Actively Recruiting
Allergy to Tree Pollen
0 Actively Recruiting
Respiratory Allergy
0 Actively Recruiting
House Dust Mite Allergy
0 Actively Recruiting
Hay Fever
1 Actively Recruiting
Phase 3
Ragweed Allergy
0 Actively Recruiting
Chronic Urticaria
1 Actively Recruiting
Phase 4
Perennial Allergic Rhinitis (PAR)
1 Actively Recruiting
Phase 3
Grass Allergy
0 Actively Recruiting
Allergy to Mold
0 Actively Recruiting
Zerviate Reviews: What are patients saying about Zerviate?
5Patient Review
6/18/2020 Zerviate is the only thing that has worked for my itchy eyes. I had instant relief and would recommend to anyone else suffering from allergies.
4.3Patient Review
4/14/2021 I found it effective and took it on several occasions.
4Patient Review
4/14/2021 This worked for me and I'm glad it did.
Patient Q&A Section about zerviate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Zerviate a prescription?
"Zerviate is a prescription medicine that is used to relieve the symptoms of Allergic Conjunctivitis, such as itchiness, redness, and watering of the eyes."
Answered by AI
Is Zerviate over the counter?
"Zerviate (cetirizine) is not available over the counter (OTC). It is only available by prescription from your provider."
Answered by AI
How long can I use Zerviate?
"Is ZERVIATE effective and safe for children to use?
Yes. The safety and effectiveness of ZERVIATE have been evaluated in clinical studies involving children. These studies showed that children experienced no pain when taking ZERVIATE. ZERVIATE is approved for use in children aged 2-17."
Answered by AI
What is Zerviate used for?
"ZERVIATE is a medication for treating itchy eyes that are swollen and irritated due to allergies. instill two drops of ZERVIATE, in each eye, Twice a day."
Answered by AI