Vyvanse

Attention Deficit Hyperactivity Disorder, Binge-Eating Disorder
Treatment
20 Active Studies for Vyvanse

What is Vyvanse

LisdexamfetamineThe Generic name of this drug
Treatment SummaryLisdexamfetamine (also known as Vyvanse) is a medication used to treat attention deficit hyperactivity disorder (ADHD). It is made up of the essential amino acid L-lysine and the psychostimulant d-amphetamine. This drug works by increasing attention span, decreasing restlessness, and improving focus in people with ADHD. It is designed to be harder to abuse than other stimulants due to its delayed release after ingestion. After being taken orally, it is broken down into L-lysine and d-amphetamine by red blood cells, with the amount of d-amphetamine released into the bloodstream
Vyvanseis the brand name
image of different drug pills on a surface
Vyvanse Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vyvanse
Lisdexamfetamine
2007
20

Effectiveness

How Vyvanse Affects PatientsLisdexamfetamine dimesylate is a drug that is broken down into _d-amphetamine_ in the body. This stimulates the central nervous system and helps to increase alertness, focus, energy, and motivation. It works by releasing the neurotransmitters dopamine and norepinephrine from their storage sites in the brain.
How Vyvanse works in the bodyLisdexamfetamine is a drug that helps with ADHD. It works by increasing the amount of norepinephrine and dopamine in the brain. These are chemicals that help you to focus and pay attention. It does this by blocking a protein that would normally clear these chemicals out of the brain. This results in more of these chemicals staying in the brain, which can help you focus better. It also works on a receptor called the trace amine-associated receptor 1, but scientists are still learning about this pathway.

When to interrupt dosage

The measure of Vyvanse is contingent upon the diagnosed affliction. The amount of dosage will fluctuate as per the mode of delivery represented in the table beneath.
Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
20.0 mg, , 70.0 mg, 50.0 mg, 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, chewable, Tablet, chewable - Oral
Binge-Eating Disorder
20.0 mg, , 70.0 mg, 50.0 mg, 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, chewable, Tablet, chewable - Oral

Warnings

Vyvanse Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Open-angle glaucoma
Do Not Combine
advanced arteriosclerosis
Do Not Combine
Agitation
Do Not Combine
Hypertensive disease
Do Not Combine
Drug abuse
Do Not Combine
Hyperthyroidism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Lisdexamfetamine may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Lisdexamfetamine may interact with Pulse Frequency
There are 20 known major drug interactions with Vyvanse.
Common Vyvanse Drug Interactions
Drug Name
Risk Level
Description
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Lisdexamfetamine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Lisdexamfetamine.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Lisdexamfetamine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Lisdexamfetamine.
Flecainide
Major
The metabolism of Flecainide can be decreased when combined with Lisdexamfetamine.
Vyvanse Toxicity & Overdose RiskTaking too much amphetamine can cause restlessness, shaking, increased reflexes, rapid breathing, confusion, aggression, hallucinations, extreme body temperature, and muscle breakdown. It can also cause problems with the heart and blood vessels, including abnormal heart rhythms, high or low blood pressure, and shock. Other symptoms include nausea, vomiting, diarrhea, and stomach cramps. Taking very large doses can lead to death. Long-term use of amphetamine can damage nerve fibers in animals, but it is not known if this happens in humans. The toxic dose in rats is 7,060 mg/kg and in mice is 3,450 mg/
image of a doctor in a lab doing drug, clinical research

Vyvanse Novel Uses: Which Conditions Have a Clinical Trial Featuring Vyvanse?

81 active investigations are currently assessing the potential of Vyvanse to counteract Binge Eating Disorder (BED).
Condition
Clinical Trials
Trial Phases
Binge-Eating Disorder
2 Actively Recruiting
Phase 1, Phase 2
Attention Deficit Hyperactivity Disorder
65 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 2, Phase 1, Early Phase 1

Vyvanse Reviews: What are patients saying about Vyvanse?

5Patient Review
8/22/2022
Vyvanse for Attention Deficit Disorder with Hyperactivity
Our son is eight years old and he's been taking this medication for two years. It's really helped him become more calm, which has made a big difference in his life.
4.7Patient Review
2/18/2022
Vyvanse for Attention Deficit Disorder with Hyperactivity
Vyvanse is the best ADHD medication that I have tried. It lasts a long time, works well, and has manageable side effects. You can't really judge an ADHD medicine within the first year of taking it, but I took Vyvanse for years! The only drawback is that it is very expensive and few insurances cover it.
4.3Patient Review
4/30/2022
Vyvanse for Attention Deficit Disorder with Hyperactivity
I started this medication 3 months ago. It helped me to concentrate and function, but I developed some unpleasant side effects because of it. I now have Raynauds, and I experience joint pain and pins and needles in my skin since going to 40mg. Other than the side effects, it’s worth it to try! My 10 year old is also on it and has had no side effects.
3.3Patient Review
4/27/2022
Vyvanse for Attention Deficit Disorder with Hyperactivity
I've been taking Vyvanse for a few weeks now and I definitely notice an improvement in my focus. However, the side effects are really harsh. I've felt dizzy, tired, nauseous, and even like I have arthritis! It's a tough decision to make whether the benefits are worth the drawbacks.
2.3Patient Review
1/28/2022
Vyvanse for Attention Deficit Disorder with Hyperactivity
Vyvanse helped me focus at work, but I couldn't sleep while on it. Switching to Azstarys was a great decision because it lets me get the productivity benefits without sacrificing my rest.
View All Reviews
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Patient Q&A Section about vyvanse

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Vyvanse make you do?

"Vyvanse increases the levels of norepinephrine and dopamine in your brain, which has the effect of stimulating your attention span."

Answered by AI

Is Vyvanse good for anxiety?

"If a child is having trouble with attention and is also anxious, the medication Vyvanse may help to reduce symptoms. However, Vyvanse is not a medication for anxiety specifically. In some cases, stimulant medications such as Vyvanse can actually increase anxiety in children who take them."

Answered by AI

How does Vyvanse make you feel?

"Amphetamines like Vyvanse can lead to a sense of euphoria or happiness. They can also help people feel more focused and alert. However, people may misuse these drugs to get more of these effects, which can lead to dependence and withdrawal symptoms."

Answered by AI

Clinical Trials for Vyvanse

Have you considered Vyvanse clinical trials? We made a collection of clinical trials featuring Vyvanse, we think they might fit your search criteria.
Have you considered Vyvanse clinical trials? We made a collection of clinical trials featuring Vyvanse, we think they might fit your search criteria.
Have you considered Vyvanse clinical trials? We made a collection of clinical trials featuring Vyvanse, we think they might fit your search criteria.
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