Vontrol

Vertigo, Disease, Nausea + 4 more
Treatment
11 Active Studies for Vontrol

What is Vontrol

DiphenidolThe Generic name of this drug
Treatment SummaryDiphenidol is a prescription drug that helps to prevent vomiting and dizziness. Taking too much diphenidol can be dangerous, especially for children.
Vontrolis the brand name
Vontrol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vontrol
Diphenidol
2006
1

Effectiveness

How Vontrol Affects PatientsDiphenidol is used to help relieve nausea and vomiting. It works by targeting the part of the brain involved in sensing motion and preventing the feeling of sickness.
How Vontrol works in the bodyThe exact way diphenidol works is not clear, but it is thought to reduce the stimulation of your body's balance system and have a calming effect. It also may affect a part of the brain that controls nausea. Diphenidol does not have any significant calming, tranquilizing, or allergy-fighting effects. It does have a mild effect on your body's peripheral nerves.

When to interrupt dosage

The suggested measure of Vontrol is contingent upon the diagnosed situation, for instance Nausea, Labyrinth and Acrodynia. The dosage may differ, according to the procedure of delivery (e.g. Tablet or Tablet - Oral) featured in the table beneath.
Condition
Dosage
Administration
Labyrinth
, 25.0 mg
Oral, , Tablet, Tablet - Oral
Vertigo
, 25.0 mg
Oral, , Tablet, Tablet - Oral
Nausea
, 25.0 mg
Oral, , Tablet, Tablet - Oral
Vomiting
, 25.0 mg
Oral, , Tablet, Tablet - Oral
Acrodynia
, 25.0 mg
Oral, , Tablet, Tablet - Oral
Disease
, 25.0 mg
Oral, , Tablet, Tablet - Oral
Nausea
, 25.0 mg
Oral, , Tablet, Tablet - Oral

Warnings

There are 20 known major drug interactions with Vontrol.
Common Vontrol Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Diphenidol is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Diphenidol is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Diphenidol is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Diphenidol is combined with Glycopyrronium.
Ipratropium
Major
The risk or severity of adverse effects can be increased when Diphenidol is combined with Ipratropium.
Vontrol Toxicity & Overdose RiskSigns of an overdose on Tramadol may include extreme tiredness, difficulty breathing, and extreme drowsiness.

Vontrol Novel Uses: Which Conditions Have a Clinical Trial Featuring Vontrol?

11 ongoing studies are examining the potential of Vontrol in providing relief from Nausea, Acrodynia and associated Nausea.
Condition
Clinical Trials
Trial Phases
Nausea
0 Actively Recruiting
Disease
1 Actively Recruiting
Not Applicable
Vomiting
1 Actively Recruiting
Not Applicable
Labyrinth
0 Actively Recruiting
Nausea
1 Actively Recruiting
Not Applicable
Acrodynia
2 Actively Recruiting
Phase 2, Phase 3
Vertigo
7 Actively Recruiting
Not Applicable, Phase 2, Phase 1

Patient Q&A Section about vontrol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How often can you take Difenidol?

"Adults: 25 to 50 milligrams (mg) every four hours as needed."

Answered by AI

What is Vontrol used for?

"The medication 'Vontrol' is effective in controlling nausea and vomiting associated with postoperative states, malignant neoplasms, and labyrinthine disturbances."

Answered by AI

What is Difenidol 25mg?

"This medication can help alleviate symptoms of Meniere's disease, as well as dizziness, nausea, and vomiting associated with ear surgery or other ear disorders. However, it is not effective in treating nausea and vomiting caused by pregnancy."

Answered by AI

What is Diphenidol used for?

"Diphenidol is used to relieve or prevent nausea, vomiting, and dizziness caused by certain medical problems."

Answered by AI

Clinical Trials for Vontrol

Image of Northwestern Memorial Hospital in Chicago, United States.

Emergency Department Physical Therapy for Dizziness

18+
All Sexes
Chicago, IL
This is a multi-site feasibility trial of an embedded emergency department (ED) physical therapy care model for dizziness at two EDs in the Northwestern Medicine and University of Utah Health systems. The study intervention (embedded ED physical therapy) is a reconceptualization of the traditional outpatient physical therapy care model in which we place a physical therapist directly in the ED to initiate timely care for patients with dizziness; we previously evaluated this intervention in a single center randomized trial for low back pain. This multi-site feasibility trial will be comprised of 9 months of active intervention and 12 months of longitudinal data collection. The two sites will be parallel randomized 1:1 to receive either the embedded ED physical therapy condition (intervention, n=1) or usual care (control, n=1) via simple randomization. This trial focuses on feasibility outcomes - such as our ability to enroll participants, deliver the intervention with fidelity, and collect longitudinal patient-reported outcome data and electronic health record data.
Waitlist Available
Has No Placebo
Northwestern Memorial Hospital (+1 Sites)
Image of Vanderbilt University Medical Center in Nashville, United States.

AW-D Tool for Postoperative Nausea and Vomiting

18+
All Sexes
Nashville, TN
The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult patients who have planned surgery with general anesthesia. The main aim is to improve PONV, establishing a scalable Clinical Decision Support (CDS) Tool for personalized PONV prevention. The primary hypothesis is that, compared with standard care, the Anesthesia Workflow-Driven Clinical Decision Support Tool for Personalized PONV Prevention will be associated with a significant improvement in the rate of appropriate administration of PONV prophylaxis and a significant decrease in the incidence of PONV. This study will evaluate a new clinical decision support (CDS) tool designed to improve how and when PONV prevention strategies are used. Unlike traditional tools that provide generic, one-time alerts, this new system is integrated into the electronic health record (EHR) and delivers timely, targeted reminders to anesthesia providers at key moments during a patient's surgical care-such as before surgery begins, after anesthesia is given, and before the patient wakes up. These alerts are based on each patient's individual risk for PONV and are intended to support, not replace, clinical judgment. The study will use a crossover design over 12 months, alternating between periods when the tool is active and when it is not. The goal is to determine whether this time-sensitive, workflow-integrated tool can lead to better adherence to best practices and improved patient outcomes.
Recruiting
Has No Placebo
Vanderbilt University Medical CenterMiklos Kertai, M.D., Ph.D.
Image of Banner - University Medical Center South in Tucson, United States.

Dexmedetomidine + Dexamethasone for Postoperative Pain

18 - 75
All Sexes
Tucson, AZ
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control, the duration of their nerve blocks, as well as the avoidance of opioid medications and subsequently their undesirable side effects. The researchers hypothesize that dexmedetomidine and dexamethasone (Dex-Dex) will work synergistically as adjuncts in a low, non-weight based formula. This would allow the investigators to improve patient satisfaction by providing them with a superior means of pain control that is longer in duration with a decreased probability of unwanted side effects. The proposed clinical study will be a prospective, randomized control trial.
Phase 1 & 2
Waitlist Available
Banner - University Medical Center SouthRonald Tang, MD
Have you considered Vontrol clinical trials? We made a collection of clinical trials featuring Vontrol, we think they might fit your search criteria.Go to Trials
Image of James A Haley VA Hospital in Tampa, United States.

Vestibular Rehabilitation Therapy for Dizziness from Concussion

18+
All Sexes
Tampa, FL
The goal of this clinical trial is to compare outcomes for standard vestibular rehabilitation home program to a digital vestibular rehabilitation home program in adults with dizziness related to mild traumatic brain injury (mTBI). The main question is whether participants who use the digital format of vestibular rehabilitation improve to a greater extent at discharge than those who use the standard format. Participants will undergo a customized vestibular rehabilitation home exercise program per standard of care, consisting of gaze stabilization, habituation, balance and gait exercises, and endurance training under the supervision of a physical therapist. Participants will complete the gaze stabilization and habituation exercises 2-3 times per day and the balance and gait exercises 1 time per day for 4 weeks. Participants will be tested before and after the 4-week intervention. At the initial session, the researcher will perform standard clinical tests of the inner ear balance system. Also at the initial session, the researcher will perform standard clinical tests of balance and walking and questionnaires about the impact of dizziness on daily activities. At the final session, the researcher will repeat the tests of balance and walking and questionnaires. Three months after completing the intervention participants will complete an online questionnaire about the impact of dizziness on daily activities.
Recruiting
Has No Placebo
James A Haley VA Hospital (+2 Sites)
Image of UCLA in Westwood, United States.

Brain Stimulation for Post-Concussion Syndrome

18 - 65
All Sexes
Westwood, CA
The goal of this study is to investigate a new treatment for chronic symptoms after concussion or mild traumatic brain injury in people aged 18-65 years old. Chronic symptoms could include dizziness, headache, fatigue, brain fog, memory difficulty, sleep disruption, irritability, or anxiety that occurred or worsened after the injury. These symptoms can interfere with daily functioning, causing difficulty returning to physical activity, work, or school. Previous concussion therapies have not been personalized nor involved direct treatments to the brain itself. The treatment being tested in the present study is a noninvasive, personalized form of brain stimulation, called transcranial magnetic stimulation (TMS). The investigators intend to answer the questions: 1. Does personalized TMS improve brain connectivity after concussion? 2. Does personalized TMS improve avoidance behaviors and chronic concussive symptoms? 3. Do the improvements last up to 2 months post-treatment? 4. Are there predictors of treatment response, or who might respond the best? Participants will undergo 14 total visits to University of California Los Angeles (UCLA): 1. One for the baseline symptom assessments and magnetic resonance imaging (MRI) 2. Ten for TMS administration 3. Three for post-treatment symptom assessments and MRIs Participants will have a 66% chance of being assigned to an active TMS group and 33% chance of being assigned to a sham, or inactive, TMS group. The difference is that the active TMS is more likely to cause functional changes in the brain than the inactive TMS.
Phase 2
Waitlist Available
UCLA (+1 Sites)
Image of Johns Hopkins University School of Medicine in Baltimore, United States.

Slower MRI Machine Entry for Vertigo

18+
All Sexes
Baltimore, MD
Vertigo, dizziness, and imbalance are commonly reported by patients and technologists when near high-field strength magnets (\>4 Tesla, T) used for magnetic resonance imaging (MRI) (1-5) Prior research from the investigators has established that the mechanism is likely a Lorentz force occurring in the inner ear, as a result of interactions with normal electrical currents in the inner ear and the strong static magnetic field of the MRI machine. The investigators have recently developed preliminary data to suggest that slower rates of entry into the magnetic field can greatly attenuate the sensations of vertigo. The explanation for this is that the rates of vestibular adaptation exceed that of the stimulus, allowed a reduction or elimination of the symptoms of vertigo. The aim of this study is to recruit individuals who are already getting an MRI scan as part of other research studies to randomize the rate of entry into and exit from the static magnetic field (i.e., before and after imaging is performed). The usual rate of entry is 20 seconds. This will be increased to one, two or three minutes. The investigators will record subjective sensations of dizziness and vertigo associated with the entry into the MRI.
Recruiting
Has No Placebo
Johns Hopkins University School of MedicineBryan Ward, MD
Image of University of British Columbia in Vancouver, Canada.

Virtual Reality Therapy for Vertigo

18+
All Sexes
Vancouver, Canada
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of adjunct take-home head-mounted display (HMD) virtual reality (VR) therapy in improving patient symptomatology. Fifty patients meeting inclusion criteria will be recruited from the principal investigator's neurotology clinic. Baseline symptomatology questionnaires will be completed, followed by random allocation to virtual reality and control groups. Vestibular rehabilitation and virtual reality protocols will be adhered to for 4 to 8 weeks, followed by symptomatology questionnaires. Data analysis will be conducted to answer the study's objectives.
Recruiting
Has No Placebo
University of British ColumbiaDesmond A Nunez, MD, MBA
Have you considered Vontrol clinical trials? We made a collection of clinical trials featuring Vontrol, we think they might fit your search criteria.Go to Trials
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